Corneal Tomography Multivariate Index (CTMVI) effectively distinguishes healthy corneas from those susceptible to ectasia

2021 ◽  
Vol 70 ◽  
pp. 102995
Author(s):  
Gildasio Castello de Almeida Jr ◽  
Rodrigo Capobianco Guido ◽  
Jogi Suda Neto ◽  
João Marcos Rosa ◽  
Lilian Castiglioni ◽  
...  
Keyword(s):  
2021 ◽  
pp. 112067212199767
Author(s):  
Iva Krolo ◽  
Aida Kasumović ◽  
Ivana Radman ◽  
Pavao Pavić

Purpose: Ocular features of Alport syndrome include anterior lenticonus, posterior polymorphous corneal dystrophy, and fleck-and-dot retinopathy in most cases. Keratoconus in such patients has been rarely mentioned in previous studies. To our knowledge, this is the first report of corneal cross-linking for halting the progression of keratoconus in a patient with Alport syndrome. Case report: A 22-year-old male was referred for his initial corneal topography, after he was already prescribed with rigid gas-permeable contact lenses. Alport syndrome was diagnosed in his infancy and gene COL4A5 mutation was confirmed. Ophthalmological evaluation confirmed keratoconus. One-year follow-up showed a progression on his right eye and standard corneal cross-linking was performed. Stabilization of the disease marked by normalization in visual function and corneal tomography values was noticed 1 year after the procedure. Conclusions: When diagnosing ocular clinical findings of Alport syndrome, keratoconus should be considered. Standard corneal cross-linking protocol can halt its progression.


2018 ◽  
Vol 30 (1) ◽  
pp. 139-146 ◽  
Author(s):  
Guilherme Andrade do Nascimento Rocha ◽  
Paulo Ferrara de Almeida Cunha ◽  
Leonardo Torquetti Costa ◽  
Luciene Barbosa de Sousa

Importance: This study shows that a newer long-arc length intrastromal corneal ring segment is efficient and safe for keratoconus treatment. Background: To evaluate visual, tomographic results and complications of a 320-degree intrastromal corneal ring segment implantation with the femtosecond laser for keratoconus treatment. Design: A prospective, nonrandomized, and interventional study. Participants: A total of 34 eyes of 31 patients diagnosed with keratoconus were enrolled. Methods: Patients were divided into two groups based on the strategy used for 320-degree intrastromal corneal ring segment thickness selection. In one group, this selection was based on spherical equivalent (SE group) and in the other on the mean asphericity (Q group). The uncorrected and corrected distance visual acuities, spherical equivalent, K1, K2, Km, Kmax, and mean asphericity ( Q) on corneal tomography were evaluated preoperatively and at 3 and 6 months postoperatively. For astigmatism improvement, we analyzed the corneal tomographic vectorial astigmatism change preoperatively and at 6 months postoperatively. The mean follow-up period was 6.63 ± 0.96 months. Results: The mean uncorrected distance visual acuity and corrected distance visual acuity improved with a significant spherical equivalent improvement ( p < 0.05), with no differences between the 320-degree intrastromal corneal ring segment groups. All corneal tomographic parameters improved significantly ( p < 0.05) between the preoperative and postoperative intervals, with a significant better performance when we used spherical equivalent for the 320-degree intrastromal corneal ring segment thickness selection. Finally, the mean vectorial corneal tomographic astigmatism significantly improved after 6 months, again with no differences between groups. Conclusion: This study suggests that implanting a 320-degree intrastromal corneal ring segment is a safe and effective procedure for treating patients with keratoconus. It also suggests that for thickness selection spherical equivalent is the better strategy.


2021 ◽  
Vol 8 ◽  
Author(s):  
Belén Alfonso-Bartolozzi ◽  
Carlos Lisa ◽  
Luis Fernández-Vega-Cueto ◽  
David Madrid-Costa ◽  
José F. Alfonso

Purpose: To assess the outcomes of implanting a new polymethylmethacrylate (PMMA) ring (Neoring; AJL Ophthalmic) in pre-descemet deep anterior lamellar keratoplasty (PD-DALK) procedure for moderate-advanced keratoconus.Methods: This prospective study included 10 eyes of 10 patients with moderate-advanced keratoconus who underwent PD-DALK with Neoring implantation. Neoring was implanted in a pre-descemetic pocket. The post-operative examination included refraction, corrected distance visual acuity (CDVA), corneal tomography, and endothelial cell density (ECD). The root mean squares (RMSs) for coma-like aberrations and spherical aberration were evaluated for a pupil size of 4.5 mm. The junctional graft (Tg) and host (Th) thicknesses were measured. The post-operative follow-up was 24 months.Results: Post-operative CDVA was 0.82 ± 0.14 (decimal scale), 100% of the eyes achieved a CDVA of 0.7 (decimal scale). The refractive cylinder was −2.86 ± 1.65 2-years after surgery. No eyes had a post-operative refractive cylinder ≥5.00 D and in five eyes (50%), it was ≤2.50 D. At the last visit, the mean keratometry was 45.64 ± 1.96 D, the RMS for coma-like aberrations was 0.30 ± 0.15 μm and spherical aberration was 0.22 ± 0.09. The mean ECD remains without changes over the follow-up (P = 0.07). At the last visit, Tg and Th were 679.9 ± 39.0 and 634.8 ± 41.2 μm, respectively. The thickness of the complex (host-Neoring) was 740.6 ± 35.6 μm. In all cases, this thickness was thicker than Tg.Conclusion: The results of this study suggest that PD-DALK along Neoring implantation is a viable, effective, and safe option to optimize the post-operative results for moderate-severe keratoconus.


2018 ◽  
Vol 43 (6) ◽  
pp. 709-716 ◽  
Author(s):  
Simon Schröder ◽  
Stephanie Mäurer ◽  
Timo Eppig ◽  
Berthold Seitz ◽  
Kathrin Rubly ◽  
...  
Keyword(s):  

2018 ◽  
Vol 34 (8) ◽  
pp. 547-550 ◽  
Author(s):  
Daniela Lyra ◽  
Guilherme Ribeiro ◽  
Leonardo Torquetti ◽  
Paulo Ferrara ◽  
Aydano Machado ◽  
...  

2021 ◽  
Author(s):  
Jun Zhang ◽  
Li Zheng ◽  
Xia Zhao ◽  
Jindong Gao ◽  
Yixuan Zhang ◽  
...  

Abstract Background: The aim of the study is to introduce the acquisition of target diameter spherical aberration in term of diopter (SA-D), and to report the distribution of SA-D in patients with myopia. Methods: This was a retrospective study of patients who underwent therapeutic refractive surgery at Hangzhou MSK Eye Hospital between 10/2018 and 12/2018. The corneal Q values and apex curvature of the anterior and posterior surfaces were measured at 3.0, 4.0, 5.0, 6.0, and 7.0 mm of aperture diameters using corneal tomography. Results: In total, 531 females and 384 males were included. The anterior corneal SA-D values were: 0.39±0.19, 0.63±0.27, 0.97±0.36, 0.90±0.30, and 0.83±0.29 D at 3.0, 4.0, 5.0, 6.0, and 7.0 mm; the whole corneal values were: 0.26±0.20, 0.44±0.27, 0.70±0.36, 0.66±0.30, and 0.59±0.28 D. SE was positively correlated with anterior corneal peripheral Q-value and SA-D and whole ocular peripheral SA-D. Conclusions: Both corneal anterior and posterior Q values of myopia patients decreased while diameter increased. Both anterior and whole corneal SA-D increases significantly while diameter increases within 5mm, and both anterior and whole corneal SA-D outside 5mm decreases slightly while diameter increases. SE was positively correlated with anterior corneal peripheral Q-value and SA-D and whole ocular peripheral SA-D.


2010 ◽  
Vol 27 (7) ◽  
pp. 502-508 ◽  
Author(s):  
Farid Karimian ◽  
Sepehr Feizi ◽  
Azadeh Doozandeh ◽  
Amir Faramarzi ◽  
Mehdi Yaseri

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Simon Schröder ◽  
Timo Eppig ◽  
Weidi Liu ◽  
Jens Schrecker ◽  
Achim Langenbucher

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