The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism

Cancer Letters ◽

10.1016/j.canlet.2021.11.022 ◽

2021 ◽

Author(s):

Hassan Choucair ◽

Md Khalilur Rahman ◽

Balasubrahmanyam Umashankar ◽

Yassir Al-Zubaidi ◽

Kirsi Bourget ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Fatty Acid ◽

Endoplasmic Reticulum Stress ◽

Tumor Cells ◽

Mitochondrial Targeting

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Inhibition of Fatty Acid Synthase Induces Endoplasmic Reticulum Stress in Tumor Cells

Cancer Research ◽

10.1158/0008-5472.can-06-1794 ◽

2007 ◽

Vol 67 (3) ◽

pp. 1262-1269 ◽

Cited By ~ 120

Author(s):

Joy L. Little ◽

Frances B. Wheeler ◽

Diane R. Fels ◽

Constantinos Koumenis ◽

Steven J. Kridel

Keyword(s):

Endoplasmic Reticulum ◽

Fatty Acid ◽

Endoplasmic Reticulum Stress ◽

Tumor Cells ◽

Fatty Acid Synthase

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Faculty Opinions recommendation of Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108809.564937 ◽

2008 ◽

Author(s):

Raghavendra Mirmira

Keyword(s):

Endoplasmic Reticulum ◽

Fatty Acid ◽

Endoplasmic Reticulum Stress ◽

Beta Cells ◽

Pancreatic Islet ◽

Islet Beta Cells ◽

Pancreatic Islet Beta Cells ◽

Induced Apoptosis

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BMS309403 decreases fatty acid-induced endoplasmic reticulum stress-associated inflammation in skeletal muscle

Atherosclerosis ◽

10.1016/j.atherosclerosis.2018.06.606 ◽

2018 ◽

Vol 275 ◽

pp. e197

Author(s):

R. Rodriguez-calvo ◽

A. Bosquet ◽

J. Girona ◽

S. Guaita-esteruelas ◽

M. Heras ◽

...

Keyword(s):

Skeletal Muscle ◽

Endoplasmic Reticulum ◽

Fatty Acid ◽

Endoplasmic Reticulum Stress

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Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway

Infection Genetics and Evolution ◽

10.1016/j.meegid.2020.104552 ◽

2020 ◽

Vol 85 ◽

pp. 104552

Author(s):

Jialin Yu ◽

Chenjie Ma ◽

Yanan Xu ◽

Lu Han ◽

Xiaoling Wu ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Fatty Acid ◽

Endoplasmic Reticulum Stress ◽

Fatty Acid Binding Protein ◽

Bacillus Calmette Guerin ◽

Fatty Acid Binding ◽

Acid Binding Protein ◽

Raw264.7 Cell ◽

Endoplasmic Reticulum Stress Pathway ◽

Stress Pathway

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Involvement of both caspase-8 and Noxa-activated pathways in endoplasmic reticulum stress-induced apoptosis in triple-negative breast tumor cells

Cell Death and Disease ◽

10.1038/s41419-017-0164-7 ◽

2018 ◽

Vol 9 (2) ◽

Cited By ~ 8

Author(s):

Ana Cano-González ◽

Marta Mauro-Lizcano ◽

Daniel Iglesias-Serret ◽

Joan Gil ◽

Abelardo López-Rivas

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Tumor Cells ◽

Breast Tumor ◽

Triple Negative ◽

Caspase 8 ◽

Breast Tumor Cells ◽

Induced Apoptosis

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Dietary fatty acid palmitate induces endoplasmic reticulum stress, chondrocyte death and cartilage lesions in the knee joint of mice

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2020.02.103 ◽

2020 ◽

Vol 28 ◽

pp. S68

Author(s):

L. Tan ◽

C. Carlson ◽

R. Yammani

Keyword(s):

Endoplasmic Reticulum ◽

Fatty Acid ◽

Endoplasmic Reticulum Stress ◽

Knee Joint ◽

Dietary Fatty Acid ◽

Cartilage Lesions ◽

Chondrocyte Death ◽

And Cartilage

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Membrane lipid polyunsaturation mediated by FATTY ACID DESATURASE 2 ( FAD 2 ) is involved in endoplasmic reticulum stress tolerance in Arabidopsis thaliana

The Plant Journal ◽

10.1111/tpj.14338 ◽

2019 ◽

Vol 99 (3) ◽

pp. 478-493 ◽

Cited By ~ 5

Author(s):

Van Cam Nguyen ◽

Yuki Nakamura ◽

Kazue Kanehara

Keyword(s):

Arabidopsis Thaliana ◽

Endoplasmic Reticulum ◽

Fatty Acid ◽

Endoplasmic Reticulum Stress ◽

Stress Tolerance ◽

Fatty Acid Desaturase ◽

Membrane Lipid ◽

Fatty Acid Desaturase 2

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Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells

Molecular and Cellular Biochemistry ◽

10.1007/s11010-009-0142-1 ◽

2009 ◽

Vol 331 (1-2) ◽

pp. 31-40 ◽

Cited By ~ 99

Author(s):

Yuren Wei ◽

Dong Wang ◽

Christopher L. Gentile ◽

Michael J. Pagliassotti

Keyword(s):

Endoplasmic Reticulum ◽

Cell Death ◽

Fatty Acid ◽

Endoplasmic Reticulum Stress ◽

Saturated Fatty Acid ◽

Liver Cells ◽

Luminal Calcium

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Reduced endoplasmic reticulum luminal calcium links saturated fatty acid-mediated endoplasmic reticulum stress and cell death in liver cells

Molecular and Cellular Biochemistry ◽

10.1007/s11010-009-0187-1 ◽

2009 ◽

Vol 329 (1-2) ◽

pp. 183-184 ◽

Cited By ~ 1

Author(s):

Yuren Wei ◽

Dong Wang ◽

Christopher L. Gentile ◽

Michael J. Pagliassotti

Keyword(s):

Endoplasmic Reticulum ◽

Cell Death ◽

Fatty Acid ◽

Endoplasmic Reticulum Stress ◽

Saturated Fatty Acid ◽

Liver Cells ◽

Luminal Calcium

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The pterocarpanquinone LQB 118 induces apoptosis in tumor cells through the intrinsic pathway and the endoplasmic reticulum stress pathway

Anti-Cancer Drugs ◽

10.1097/cad.0b013e3283592da8 ◽

2013 ◽

Vol 24 (1) ◽

pp. 73-83 ◽

Cited By ~ 11

Author(s):

Thiago de Sá Bacelar ◽

Alcides J. da Silva ◽

Paulo R.R. Costa ◽

Vivian M. Rumjanek

Keyword(s):

Endoplasmic Reticulum ◽

Endoplasmic Reticulum Stress ◽

Tumor Cells ◽

Intrinsic Pathway ◽

Endoplasmic Reticulum Stress Pathway ◽

Stress Pathway

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