Monocyte chemoattractant protein-1 or macrophage inflammatory protein-1α deficiency does not affect angiotensin II-induced intimal hyperplasia in carotid artery ligation model

2007 ◽  
Vol 16 (4) ◽  
pp. 231-236 ◽  
Author(s):  
Le-Ning Zhang ◽  
Valdeci da Cunha ◽  
Baby Martin-McNulty ◽  
John Rutledge ◽  
Ronald Vergona ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Carotid Artery ◽  
Intimal Hyperplasia ◽  
Artery Ligation ◽  
Monocyte Chemoattractant Protein 1 ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein ◽  
Carotid Artery Ligation ◽  
Inflammatory Protein ◽  
Macrophage Inflammatory Protein

scholarly journals Divergent Roles of Tumor Necrosis Factor and Platelet-Activating Factor in Endotoxin-Induced Release of Monocyte Chemoattractant Protein 1 and Macrophage Inflammatory Protein 1β in Chimpanzees

1999 ◽  
Vol 67 (10) ◽  
pp. 5480-5482 ◽  
Author(s):  
Pascale E. P. Dekkers ◽  
Marcel Levi ◽  
Sander J. H. van Deventer ◽  
Tom van der Poll
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Platelet Activating Factor ◽  
Necrosis Factor Alpha ◽  
Monocyte Chemoattractant Protein 1 ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein ◽  
Inflammatory Protein ◽  
Macrophage Inflammatory Protein ◽  
Necrosis Factor

ABSTRACT A platelet-activating factor receptor antagonist reduced the release of macrophage inflammatory protein 1β (MIP-1β) during endotoxemia in chimpanzees but did not influence the secretion of monocyte chemoattractant protein 1 (MCP-1). Anti-tumor necrosis factor alpha monoclonal antibody completely prevented MCP-1 release and simultaneously enhanced the secretion of MIP-1β. Levels of MIP-1β and MCP-1 release were differentially regulated during endotoxemia.

Sign in / Sign up

Export Citation Format

Share Document