Chemoenzymatic synthesis and biological evaluation of ganglioside GM3 and lyso-GM3 as potential agents for cancer therapy

2021 ◽  
pp. 108431
Author(s):  
Tingshen Li ◽  
Xiaodan Wang ◽  
Peijie Dong ◽  
Peng Yu ◽  
Yongmin Zhang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Biological Evaluation ◽  
Chemoenzymatic Synthesis ◽  
Ganglioside Gm3 ◽  
Synthesis And Biological Evaluation

scholarly journals Design, synthesis and biological evaluation of new ganglioside GM3 analogues as potential agents for cancer therapy

2020 ◽  
Vol 189 ◽  
pp. 112065
Author(s):  
Changping Zheng ◽  
Ruyi Huang ◽  
Teodora Bavaro ◽  
Marco Terreni ◽  
Matthieu Sollogoub ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Biological Evaluation ◽  
Ganglioside Gm3 ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

Synthesis and biological evaluation of seliciclib derivatives as potent and selective CDK9 inhibitors for prostate cancer therapy

2021 ◽  
Vol 152 (1) ◽  
pp. 109-120
Author(s):  
Aisha A. Alsfouk ◽  
Hanan M. Alshibl ◽  
Najla A. Altwaijry ◽  
Bshra A. Alsfouk ◽  
Ebtehal S. Al-Abdullah
Keyword(s):  
Prostate Cancer ◽  
Cancer Therapy ◽  
Biological Evaluation ◽  
Prostate Cancer Therapy ◽  
Synthesis And Biological Evaluation

Asymmetric Synthesis and Biological Evaluation of Glycosidic Prodrugs for a Selective Cancer Therapy

ChemMedChem ◽  
2008 ◽  
Vol 3 (12) ◽  
pp. 1946-1955 ◽  
Author(s):  
Lutz F. Tietze ◽  
J. Marian von Hof ◽  
Birgit Krewer ◽  
Michael Müller ◽  
Felix Major ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Asymmetric Synthesis ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

scholarly journals Chemoenzymatic synthesis and biological evaluation of enantiomerically enriched 1-(β-hydroxypropyl)imidazolium- and triazolium-based ionic liquids

2013 ◽  
Vol 9 ◽  
pp. 516-525 ◽  
Author(s):  
Paweł Borowiecki ◽  
Małgorzata Milner-Krawczyk ◽  
Jan Plenkiewicz
Keyword(s):  
Ionic Liquids ◽  
Vinyl Acetate ◽  
Propylene Oxide ◽  
Ring Opening ◽  
Biological Evaluation ◽  
Optically Active ◽  
Chemoenzymatic Synthesis ◽  
Alkyl Bromides ◽  
Wide Range ◽  
Synthesis And Biological Evaluation

Racemic 1-(β-hydroxypropyl)azoles were prepared by solvent-free direct regioselective ring opening of 1,2-propylene oxide with imidazole or 1,2,4-triazole. Lipase-catalyzed transesterification of alcohols with vinyl acetate resulted in kinetic enantiomers resolution. Separated (S)-enantiomers of (+)-1-(1H-imidazol-1-yl)propan-2-ol and (+)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol were quaternized with alkyl bromides or iodides, yielding novel optically active ionic liquids. Racemic salts were tested against a wide range of microorganisms.

Design, synthesis and biological evaluation of novel FGFR inhibitors bearing an indazole scaffold

2015 ◽  
Vol 13 (28) ◽  
pp. 7643-7654 ◽  
Author(s):  
Jian Liu ◽  
Xia Peng ◽  
Yang Dai ◽  
Wei Zhang ◽  
Sumei Ren ◽  
...  
Keyword(s):  
Growth Factor ◽  
Cancer Therapy ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth Factor Receptor ◽  
Growth Factor Receptor ◽  
Biological Evaluation ◽  
Fibroblast Growth ◽  
Design Synthesis ◽  
Potential Target ◽  
Synthesis And Biological Evaluation

Fibroblast growth factor receptor (FGFR) is a potential target for cancer therapy.

Novel deoxy-selenylconduritols: chemoenzymatic synthesis and biological evaluation

2009 ◽  
Vol 20 (23) ◽  
pp. 2673-2676 ◽  
Author(s):  
Ana Bellomo ◽  
Ana Bertucci ◽  
Hélio Stefani ◽  
Álvaro Vázquez ◽  
David Gonzalez
Keyword(s):  
Biological Evaluation ◽  
Chemoenzymatic Synthesis ◽  
Synthesis And Biological Evaluation
Sign in / Sign up

Export Citation Format

Share Document