Cloning of estrogen receptor alpha and aromatase cDNAs and gene expression in turtles (Chrysemys picta and Pseudemys scripta) exposed to different environments

2011 ◽  
Vol 154 (3) ◽  
pp. 213-225 ◽  
Author(s):  
Emily C. Marquez ◽  
Nikki Traylor-Knowles ◽  
Apolonia Novillo-Villajos ◽  
Ian P. Callard
Keyword(s):  
Gene Expression ◽  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Chrysemys Picta ◽  
Receptor Alpha ◽  
Pseudemys Scripta

scholarly journals Identification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2.

2009 ◽  
Vol 10 (1) ◽  
pp. 36 ◽  
Author(s):  
Christopher C Williams ◽  
Aninda Basu ◽  
Abeer El-Gharbawy ◽  
Latonya M Carrier ◽  
Carolyn L Smith ◽  
...  
Keyword(s):  
Gene Expression ◽  
Estrogen Receptor ◽  
Protein Kinase ◽  
Protein Kinase Ck2 ◽  
Estrogen Receptor Alpha ◽  
Phosphorylation Sites ◽  
Receptor Alpha ◽  
Kinase Ck2

scholarly journals Repression of ESR1 through Actions of Estrogen Receptor Alpha and Sin3A at the Proximal Promoter

2009 ◽  
Vol 29 (18) ◽  
pp. 4949-4958 ◽  
Author(s):  
Stephanie J. Ellison-Zelski ◽  
Natalia M. Solodin ◽  
Elaine T. Alarid
Keyword(s):  
Gene Expression ◽  
Estrogen Receptor ◽  
Transcription Factor ◽  
Rna Polymerase Ii ◽  
Transcriptional Repression ◽  
Estrogen Receptor Alpha ◽  
Proximal Promoter ◽  
Receptor Alpha ◽  
Expression Of Genes ◽  
Activation Of Transcription

ABSTRACT Gene expression results from the coordinated actions of transcription factor proteins and coregulators. Estrogen receptor alpha (ERα) is a ligand-activated transcription factor that can both activate and repress the expression of genes. Activation of transcription by estrogen-bound ERα has been studied in detail, as has antagonist-induced repression, such as that which occurs by tamoxifen. How estrogen-bound ERα represses gene transcription remains unclear. In this report, we identify a new mechanism of estrogen-induced transcriptional repression by using the ERα gene, ESR1. Upon estrogen treatment, ERα is recruited to two sites on ESR1, one distal (ENH1) and the other at the proximal (A) promoter. Coactivator proteins, namely, p300 and AIB1, are found at both ERα-binding sites. However, recruitment of the Sin3A repressor, loss of RNA polymerase II, and changes in histone modifications occur only at the A promoter. Reduction of Sin3A expression by RNA interference specifically inhibits estrogen-induced repression of ESR1. Furthermore, an estrogen-responsive interaction between Sin3A and ERα is identified. These data support a model of repression wherein actions of ERα and Sin3A at the proximal promoter can overcome activating signals at distal or proximal sites and ultimately decrease gene expression.

scholarly journals Estrogen receptor-alpha gene expression in the cortex: Sex differences during development and in adulthood

2011 ◽  
Vol 59 (3) ◽  
pp. 353-357 ◽  
Author(s):  
Melinda E. Wilson ◽  
Jenne M. Westberry ◽  
Amanda L. Trout
Keyword(s):  
Gene Expression ◽  
Estrogen Receptor ◽  
Sex Differences ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha ◽  
Estrogen Receptor Alpha Gene ◽  
Alpha Gene

scholarly journals Estrogen receptor alpha mutations in breast cancer cells cause gene expression changes through constant activity and secondary effects

2020 ◽  
pp. canres.1171.2020 ◽  
Author(s):  
Spencer Arnesen ◽  
Zannel Blanchard ◽  
Michelle M. Williams ◽  
Kristofer C. Berrett ◽  
Zheqi Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Estrogen Receptor ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Estrogen Receptor Alpha ◽  
Secondary Effects ◽  
Receptor Alpha

Unliganded estrogen receptor alpha regulates vascular cell function and gene expression

2017 ◽  
Vol 442 ◽  
pp. 12-23 ◽  
Author(s):  
Qing Lu ◽  
Gavin R. Schnitzler ◽  
Caroline S. Vallaster ◽  
Kazutaka Ueda ◽  
Stephanie Erdkamp ◽  
...  
Keyword(s):  
Gene Expression ◽  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Cell Function ◽  
Vascular Cell ◽  
Receptor Alpha

scholarly journals Protocadherin 19 (PCDH19) interacts with paraspeckle protein NONO to co-regulate gene expression with estrogen receptor alpha (ERα)

2017 ◽  
Vol 26 (11) ◽  
pp. 2042-2052 ◽  
Author(s):  
Duyen H. Pham ◽  
Chuan C. Tan ◽  
Claire C. Homan ◽  
Kristy L. Kolc ◽  
Mark A. Corbett ◽  
...  
Keyword(s):  
Gene Expression ◽  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Regulate Gene Expression ◽  
Receptor Alpha ◽  
Regulate Gene

scholarly journals Estrogen receptor alpha controls gene expression via translational offsetting

2019 ◽  
Author(s):  
Julie Lorent ◽  
Richard J Rebello ◽  
Hoef Vincent van ◽  
Mitchell G Lawrence ◽  
Krzysztof J Szkop ◽  
...  
Keyword(s):  
Gene Expression ◽  
Estrogen Receptor ◽  
Estrogen Receptor Alpha ◽  
Receptor Alpha
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