Lung Disease–Related Pulmonary Hypertension

2022 ◽  
Vol 40 (1) ◽  
pp. 77-88
Author(s):  
Kareem Ahmad ◽  
Vikramjit Khangoora ◽  
Steven D. Nathan
Keyword(s):  
Pulmonary Hypertension ◽  
Lung Disease

Hypoxic Pulmonary Vasoconstriction and Chronic Lung Disease

2013 ◽  
Vol 12 (3) ◽  
pp. 135-144 ◽  
Author(s):  
Erik R. Swenson
Keyword(s):  
Pulmonary Hypertension ◽  
Lung Disease ◽  
Hypoxic Pulmonary Vasoconstriction ◽  
World Health ◽  
Disease States ◽  
Pulmonary Vasoconstriction ◽  
Local Ventilation ◽  
Pulmonary Vascular Endothelium ◽  
Health And Disease ◽  
Health Organization

Hypoxic vasoconstriction in the lung is a unique and fundamental characteristic of the pulmonary circulation. It functions in health and disease states to better preserve ventilation-perfusion matching by diverting blood flow to better ventilated regions when local ventilation is compromised. As more areas of lung become hypoxic either with high altitude or global lung disease, then hypoxic pulmonary vasoconstriction (HPV) becomes less effective in ventilation-perfusion matching and can lead to pulmonary hypertension. HPV is intrinsic to the vascular smooth muscle and its mechanisms remain poorly understood. In addition, the pulmonary vascular endothelium, red cells, lung innervation, and numerous circulating vasoactive agents also affect the strength of HPV. This review will discuss the pathophysiology of HPV and address its role in pulmonary hypertension associated with World Health Organization Group 3 diseases. When sustained beyond many hours, HPV may initiate pulmonary vascular remodeling and lead to more fixed and less oxygen-responsive pulmonary hypertension if the hypoxic stimulus is maintained.

Impact of post-capillary pulmonary hypertension on mortality in interstitial lung disease

2021 ◽  
Author(s):  
Ryo Teramachi ◽  
Hiroyuki Taniguchi ◽  
Yasuhiro Kondoh ◽  
Tomoki Kimura ◽  
Kensuke Kataoka ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Interstitial Lung Disease ◽  
Lung Disease

Computed Tomography (CT) and Echocardiogram Prediction of Pulmonary Hypertension in Patients With Advanced Lung Disease

CHEST Journal ◽  
2010 ◽  
Vol 138 (4) ◽  
pp. 545A
Author(s):  
Shalini Nayar ◽  
Randy Chung ◽  
Melanie Chin ◽  
Hong Qian ◽  
Jonathon Leipsic ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pulmonary Hypertension ◽  
Lung Disease

The effect of pulmonary hypertension on left atrial mechanical functions in chronic obstructive lung disease

2004 ◽  
Vol 97 (2) ◽  
pp. 187-192 ◽  
Author(s):  
Mahmut Acikel ◽  
Mustafa Yilmaz ◽  
Yekta Gurlertop ◽  
Hasan Kaynar ◽  
Engin Bozkurt ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Lung Disease ◽  
Left Atrial ◽  
Obstructive Lung Disease ◽  
Chronic Obstructive Lung Disease ◽  
Chronic Obstructive

Iron Deficiency is Associated with More Severe Pulmonary Vascular Disease in Pulmonary Hypertension due to Chronic Lung Disease

CHEST Journal ◽  
2021 ◽  
Author(s):  
Jasmine Tatah ◽  
Jennifer L. Keen ◽  
Sasha Z. Prisco ◽  
Marc Pritzker ◽  
Thenappan Thenappan ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Iron Deficiency ◽  
Lung Disease ◽  
Vascular Disease ◽  
Chronic Lung Disease ◽  
Pulmonary Vascular Disease
Sign in / Sign up

Export Citation Format

Share Document