Multiple exosome RNA analysis methods for lung cancer diagnosis through integrated on-chip microfluidic system

2021 ◽  
Author(s):  
Yunxing Lu ◽  
Zhaoduo Tong ◽  
Zhenhua Wu ◽  
Xiaoyu Jian ◽  
Lin Zhou ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Diagnosis ◽  
Microfluidic System ◽  
Rna Analysis ◽  
Lung Cancer Diagnosis ◽  
Analysis Methods ◽  
On Chip

Computer-Aided Lung Cancer Diagnosis Approaches Based on Deep Learning

2018 ◽  
Vol 30 (1) ◽  
pp. 90 ◽  
Author(s):  
Peng Zhang ◽  
Xinnan Xu ◽  
Hongwei Wang ◽  
Yuanli Feng ◽  
Haozhe Feng ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Deep Learning ◽  
Cancer Diagnosis ◽  
Lung Cancer Diagnosis ◽  
Computer Aided

Biased Lung Cancer Risk Perceptions: Smokers are Misinformed

2018 ◽  
Vol 238 (5) ◽  
pp. 395-421 ◽  
Author(s):  
Nicolas R. Ziebarth
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Cancer Diagnosis ◽  
Mortality Risk ◽  
Risk Perceptions ◽  
Lung Cancer Risk ◽  
Lifetime Risk ◽  
Lung Cancer Diagnosis ◽  
Cancer Risk Perceptions ◽  
Overall Mortality

Abstract This paper empirically investigates biased beliefs about the risks of smoking. First, it confirms the established tendency of people to overestimate the lifetime risk of a smoker to contract lung cancer. In this paper’s survey, almost half of all respondents overestimate this risk. However, 80% underestimate lung cancer deadliness. In reality, less than one in five patients survive five years after a lung cancer diagnosis. Due to the broad underestimation of the lung cancer deadliness, the lifetime risk of a smoker to die of lung cancer is underestimated by almost half of all respondents. Smokers who do not plan to quit are significantly more likely to underestimate this overall mortality risk.

scholarly journals An Efficient DA-Net Architecture for Lung Nodule Segmentation

Mathematics ◽  
2021 ◽  
Vol 9 (13) ◽  
pp. 1457
Author(s):  
Muazzam Maqsood ◽  
Sadaf Yasmin ◽  
Irfan Mehmood ◽  
Maryam Bukhari ◽  
Mucheol Kim
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Ct Scan ◽  
Cancer Diagnosis ◽  
Lung Nodule ◽  
Search Space ◽  
Lung Nodules ◽  
Suggested Model ◽  
Lung Cancer Diagnosis ◽  
Segmentation Framework

A typical growth of cells inside tissue is normally known as a nodular entity. Lung nodule segmentation from computed tomography (CT) images becomes crucial for early lung cancer diagnosis. An issue that pertains to the segmentation of lung nodules is homogenous modular variants. The resemblance among nodules as well as among neighboring regions is very challenging to deal with. Here, we propose an end-to-end U-Net-based segmentation framework named DA-Net for efficient lung nodule segmentation. This method extracts rich features by integrating compactly and densely linked rich convolutional blocks merged with Atrous convolutions blocks to broaden the view of filters without dropping loss and coverage data. We first extract the lung’s ROI images from the whole CT scan slices using standard image processing operations and k-means clustering. This reduces the search space of the model to only lungs where the nodules are present instead of the whole CT scan slice. The evaluation of the suggested model was performed through utilizing the LIDC-IDRI dataset. According to the results, we found that DA-Net showed good performance, achieving an 81% Dice score value and 71.6% IOU score.

The efficacy of Raman spectroscopy in lung cancer diagnosis: the first diagnostic meta-analysis

2021 ◽  
Author(s):  
Zhang-Yan Ke ◽  
Ya-Jing Ning ◽  
Zi-Feng Jiang ◽  
Ying-ying Zhu ◽  
Jia Guo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Raman Spectroscopy ◽  
Cancer Diagnosis ◽  
Meta Analysis ◽  
Lung Cancer Diagnosis

scholarly journals Transcriptomic signals in blood prior to lung cancer focusing on time to diagnosis and metastasis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Therese H. Nøst ◽  
Marit Holden ◽  
Tom Dønnem ◽  
Hege Bøvelstad ◽  
Charlotta Rylander ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Diagnosis ◽  
Metastatic Cancer ◽  
Case Control ◽  
Functional Genomic ◽  
Blood Samples ◽  
Lung Cancer Diagnosis ◽  
Time To Diagnosis ◽  
Genomic Signals ◽  
Nested Case Control

AbstractRecent studies have indicated that there are functional genomic signals that can be detected in blood years before cancer diagnosis. This study aimed to assess gene expression in prospective blood samples from the Norwegian Women and Cancer cohort focusing on time to lung cancer diagnosis and metastatic cancer using a nested case–control design. We employed several approaches to statistically analyze the data and the methods indicated that the case–control differences were subtle but most distinguishable in metastatic case–control pairs in the period 0–3 years prior to diagnosis. The genes of interest along with estimated blood cell populations could indicate disruption of immunological processes in blood. The genes identified from approaches focusing on alterations with time to diagnosis were distinct from those focusing on the case–control differences. Our results support that explorative analyses of prospective blood samples could indicate circulating signals of disease-related processes.

scholarly journals Clinical evaluation of seven tumour markers in lung cancer diagnosis: can any combination improve the results?

1995 ◽  
Vol 72 (1) ◽  
pp. 170-173 ◽  
Author(s):  
M Plebani ◽  
D Basso ◽  
F Navaglia ◽  
M De Paoli ◽  
A Tommasini ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Clinical Evaluation ◽  
Cancer Diagnosis ◽  
Tumour Markers ◽  
Lung Cancer Diagnosis
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