Recent progress in the design principles, sensing mechanisms, and applications of small-molecule probes for nitroreductases

2020 ◽  
Vol 421 ◽  
pp. 213460 ◽  
Author(s):  
Ya-Lin Qi ◽  
Long Guo ◽  
Li-Li Chen ◽  
Hua Li ◽  
Yu-Shun Yang ◽  
...  
Nano Select ◽  
2021 ◽  
Author(s):  
Ze Zhang ◽  
Yaokun Wang ◽  
Chenkai Sun ◽  
Zitong Liu ◽  
Haiqiao Wang ◽  
...  

2021 ◽  
Vol 50 (2) ◽  
pp. 702-734
Author(s):  
Luling Wu ◽  
Jihong Liu ◽  
Ping Li ◽  
Bo Tang ◽  
Tony D. James

In this tutorial review, we will explore recent advances for the design, construction and application of two-photon excited fluorescence (TPEF)-based small-molecule probes.


Author(s):  
Zhennan Fang ◽  
Huiqiang Wei ◽  
Wenfeng Gou ◽  
Leyuan Chen ◽  
Changfen Bi ◽  
...  

Nonapoptotic types of regulated cell death have attracted widespread interest since the discovery that certain forms of cell necrosis can be regulated. In particular, research into cell necroptosis has made significant progress in connection with kidney, inflammatory, degenerative and neoplastic diseases. Inhibitors targeting the critical necroptosis-associated proteins RIPK1/3 and MLKL have been in development for more than a decade. Herein the authors compile a list of the known small-molecule inhibitors of these enzymes and representative structures of compounds co-crystallized with these proteins and put forward some thoughts regarding their future development.


2016 ◽  
Vol 76 ◽  
pp. 38-53 ◽  
Author(s):  
Yongxin Li ◽  
Huipeng Zhou ◽  
Jian Chen ◽  
Sohail Anjum Shahzad ◽  
Cong Yu

2006 ◽  
pp. 3783-3785 ◽  
Author(s):  
Jun Wang ◽  
Mahesh Uttamchandani ◽  
Junqi Li ◽  
Mingyu Hu ◽  
Shao Q. Yao

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