Oxidation of tetracycline antibiotics by peracetic acid: Reaction kinetics, mechanism, and antibacterial activity change

2021 ◽  
pp. 134190
Author(s):  
Jiabin Chen ◽  
Jie Xu ◽  
Tongcai Liu ◽  
Qi Wang ◽  
Nan Li ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Reaction Kinetics ◽  
Peracetic Acid ◽  
Activity Change ◽  
Tetracycline Antibiotics ◽  
Acid Reaction

scholarly journals Oxidation of amino acids by peracetic acid: Reaction kinetics, pathways and theoretical calculations

2018 ◽  
Vol 1 ◽  
pp. 100002 ◽  
Author(s):  
Penghui Du ◽  
Wen Liu ◽  
Hongbin Cao ◽  
He Zhao ◽  
Ching-Hua Huang
Keyword(s):  
Amino Acids ◽  
Reaction Kinetics ◽  
Peracetic Acid ◽  
Theoretical Calculations ◽  
Acid Reaction

Oxidation of β-lactam antibiotics by peracetic acid: Reaction kinetics, product and pathway evaluation

2017 ◽  
Vol 123 ◽  
pp. 153-161 ◽  
Author(s):  
Kejia Zhang ◽  
Xinyan Zhou ◽  
Penghui Du ◽  
Tuqiao Zhang ◽  
Meiquan Cai ◽  
...  
Keyword(s):  
Reaction Kinetics ◽  
Peracetic Acid ◽  
Acid Reaction

Oxidation of flavonoids by hypochlorous acid: reaction kinetics and antioxidant activity studies

2016 ◽  
Vol 50 (8) ◽  
pp. 898-908 ◽  
Author(s):  
Justyna Krych-Madej ◽  
Katarzyna Stawowska ◽  
Lidia Gebicka
Keyword(s):  
Antioxidant Activity ◽  
Reaction Kinetics ◽  
Hypochlorous Acid ◽  
Acid Reaction

Oxidation of cefalexin by thermally activated persulfate: Kinetics, products, and antibacterial activity change

2018 ◽  
Vol 354 ◽  
pp. 153-160 ◽  
Author(s):  
Yajie Qian ◽  
Gang Xue ◽  
Jiabin Chen ◽  
Jinming Luo ◽  
Xuefei Zhou ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Activity Change ◽  
Thermally Activated ◽  
Activated Persulfate

scholarly journals Gemifloxacin Is Efficacious against Penicillin-Resistant and Quinolone-Resistant Pneumococci in Experimental Meningitis

2002 ◽  
Vol 46 (5) ◽  
pp. 1607-1609 ◽  
Author(s):  
Philippe Cottagnoud ◽  
Fernando Acosta ◽  
Marianne Cottagnoud ◽  
Martin G. Täuber
Keyword(s):  
Antibacterial Activity ◽  
Standard Deviation ◽  
Bactericidal Activity ◽  
Resistant Strain ◽  
Activity Change ◽  
Standard Regimen ◽  
Pneumococcal Strain ◽  
Time Kill

ABSTRACT In experimental rabbit meningitis, gemifloxacin penetrated inflamed meninges well (22 to 33%) and produced excellent bactericidal activity (change in log10 [Δlog10] CFU/ml/h, −0.68 ± 0.30 [mean and standard deviation]), even superior to that of the standard regimen of ceftriaxone plus vancomycin (−0.49 ± 0.09 Δlog10 CFU/ml/h), in the treatment of meningitis due to a penicillin-resistant pneumococcal strain (MIC, 4 mg/liter). Even against a penicillin- and quinolone-resistant strain, gemifloxacin showed good bactericidal activity (−0.48 ± 0.16 Δlog10 CFU/ml/h). The excellent antibacterial activity of gemifloxacin was also confirmed by time-kill assays over 8 h in vitro.

Sign in / Sign up

Export Citation Format

Share Document