scholarly journals Integrated global analysis reveals a vitamin E-vitamin K1 sub-network, downstream of COLD1, underlying rice chilling tolerance divergence

Cell Reports ◽  
2021 ◽  
Vol 36 (3) ◽  
pp. 109397
Author(s):  
Wei Luo ◽  
Qing Huan ◽  
Yunyuan Xu ◽  
Wenfeng Qian ◽  
Kang Chong ◽  
...  
1989 ◽  
Vol 35 (12) ◽  
pp. 2285-2289 ◽  
Author(s):  
B E Cham ◽  
H P Roeser ◽  
T W Kamst

Abstract We describe a high-performance liquid chromatographic procedure for the simultaneous measurement of vitamins K1 and E in human serum. Delipidated human serum (free of vitamins K1 and E) was used to make standard solutions of these vitamins, and cetyl naphthoate and alpha-tocopheryl acetate were the internal standards for vitamin K1 and vitamin E, respectively. A simple, novel separation method utilizing liquid-liquid partition chromatography was used as a preparative "clean-up" procedure. Cetyl naphthoate and vitamin K1 (after post-column reduction) were detected by fluorescence, alpha-tocopheryl acetate and vitamin E by ultraviolet absorption. Sensitivity (detection limit) of the assay was 30 pg for vitamin K1 and 5 ng for vitamin E per injection. The method is specific, precise, and more rapid than previously described procedures. Within- and between-assay CVs were 8.1% and 12.9%, respectively, for vitamin K1; 3.5% and 6.0%, respectively, for vitamin E. Analytical recoveries of vitamins K1 and E were 80% and 93%, respectively, from serum and from delipidated serum (standards). The average neonatal serum concentration of vitamin K1 was 83 ng/L, 2.5 mg/L for vitamin E; for normolipidemic adults, the values were 343 ng/L and 7.9 mg/L, respectively, and for hyperlipidemic adults, 541 ng/L and 11.1 mg/L, respectively.


2020 ◽  
pp. 813-843
Author(s):  
Sean Ainsworth

This chapter presents information on neonatal drugs that begin with V, including use, pharmacology, adverse effects, fetal and infant implications of maternal treatment, treatment, and supply of Vancomycin, Varicella-zoster immunoglobulin and vaccine, Vasopressin, desmopressin, and terlipressin, Vigabatrin, Vitamin A (retinol), Vitamin B12 (hydroxocobalamin), Vitamin D (special formulations), Vitamin D (standard formulations), Vitamin E (alpha tocopherol), Vitamin K1 = phytomenadione (rINN), phytonadione (USAP), and Vitamins (multi-vitamins)


2013 ◽  
Vol 12 (2) ◽  
pp. 57-65 ◽  
Author(s):  
K Byju ◽  
G Vasundhara ◽  
V Anuradha ◽  
S M Nair ◽  
N C Kumar

Phytol, a precursor of vitamin E was identified from green algae Chaetomorpha antinnina collected from Chullickal, Kochi Kerala coast, using GC-MS. Phytol is an acyclic diterpene alcohol that can be used as a precursor for the manufacture of synthetic forms of vitamin E and vitamin K1. The compound 3,7,11,15-tetramethylhexadec-2-en-1-ol also known as phytol  which exist  naturally only in single isomeric form having molecular formula C20H40O and molecular mass 296. From the total ion chromatogram more than twenty peaks were observed, the mass spectrum of the peak at Rt 21.53 was resolved and the major fragmentations were noted. Major fragmentation were m/z 71 the base peak, m/z 296 the molecular ion peak, m/z 43, m/z 57, m/z 81, m/z 95, and m/z 123. It was found that there are some other compounds apart from this identified phytol which are more complicated in structure and cannot be characterised using GC-MS. Phytol is reported to have both antimicrobial and anticancer activities. The green algae Chaetomorpha antinnina can be proposed to be a good natural source for production of phytol.


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