Production of (S)-γ-fluoroleucine ethyl ester by enzyme mediated dynamic kinetic resolution: Comparison of batch and fed batch stirred tank processes to a packed bed column reactor

2008 ◽  
Vol 63 (1) ◽  
pp. 122-130 ◽  
Author(s):  
Matthew D. Truppo ◽  
David J. Pollard ◽  
Jeffrey C. Moore ◽  
Paul N. Devine
Keyword(s):  
Ethyl Ester ◽  
Kinetic Resolution ◽  
Packed Bed ◽  
Stirred Tank ◽  
Dynamic Kinetic Resolution ◽  
Fed Batch ◽  
Packed Bed Column ◽  
Column Reactor

Biphasic Leaching Operation for the GMDC Polymetallic Bulk Concentrate

2013 ◽  
Vol 828 ◽  
pp. 117-121
Author(s):  
Bhargav C. Patel ◽  
Devyani R. Tipre ◽  
Shailesh R. Dave
Keyword(s):  
Solvent Extraction ◽  
Metal Concentration ◽  
Ferric Iron ◽  
Packed Bed ◽  
Extraction Process ◽  
Fed Batch ◽  
Packed Bed Column ◽  
Column Reactor ◽  
Extraction Pattern ◽  
Optimized Conditions

A biphasic leaching operation was employed for the extraction of copper and zinc from the GMDC polymetallic bulk concentrate (PBC). Biogenerated ferric was used in cyclic manner for fed batch metal extractions from the PBC for four cycles under the pre-optimized conditions. Zn extraction was gradually decreased with each succeeding fed-batch cycle and it resulted in 67.89, 62.46, 47.37 and 14.74% of Zn extraction in 1st, 2nd, 3rd and 4th cycle respectively. In case of copper the extraction pattern was 86.63, 81.98, 75.58 and 46.51% Cu extraction in 1st, 2nd, 3rd and 4th cycle respectively. The leachate generated in each cycle was added in 15.0 L down flow packed bed column reactor having biofilm of developed consortium SR-BH-L for the ferrous bioregeneration and the obtained maximum IOR was 2650 mg/L/h. Overall results indicated that use of bioregenerated ferric iron from the leachate yielded as high as 52.2 and 2.6 g/L Zn and Cu respectively in the solution at the end of 4th cycle. This metal concentration in the leachate is quite acceptable for economical solvent extraction process.

scholarly journals Facile One-Pot Immobilization of a Novel Thermostable Carboxylesterase from Geobacillus uzenensis for Continuous Pesticide Degradation in a Packed-Bed Column Reactor

Catalysts ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 518
Author(s):  
Xiaohui Yang ◽  
Xudong Tang ◽  
Fengying Dong ◽  
Lin Lin ◽  
Wei Wei ◽  
...  
Keyword(s):  
Fermentation Broth ◽  
Packed Bed ◽  
The Novel ◽  
One Pot ◽  
Packed Bed Column ◽  
Column Reactor ◽  
Directed Mutation ◽  
Pyrethroid Pesticides ◽  
Pesticide Biodegradation ◽  
Continuous Reaction

The novel carboxylesterase gene (est741) was cloned from Geobacillus uzenensis. The optimal pH and temperature of Est741 were 8.0 and 50 °C. Through site-directed mutation, the optimum temperature of the mutant M160K(EstM160K) was increased from 50 to 60 °C, and showed enhanced T1/2 of 2.5 h at 70 °C in comparison to the wild type (1.3 h). EstM160K was successfully expressed Pichia pastoris and EstM160K fermentation broth was directly immobilized on epoxy-functionalized supports via a one-pot strategy to obtain the immobilized enzyme lx-EstM160K. Additionally, lx-EstM160K showed enhanced T1/2 of 36.8 h at 70 °C in comparison to free enzyme. lx-EstM160K could degrade various pyrethroid pesticides. After 40 min reaction with 50 U of the lx-EstM160K, the malathion removal was 95.8% with a malathion concentration of 20 mg/L. When 2.5 g lx-EstM160K was added to the 10 mL column reactor with the concentration of bifenthrin was 500 mg/L and the transfer rate of the pump was 0.7 mL/min, the degradation rate of lx-EstM160K to bifenthrin was 90.4%. lx-EstM160K exhibited high operational stability and maintained 72% initial activity after ten batches of continuous reaction for bifenthrin pesticide biodegradation.

scholarly journals Phenol removal by newly isolatedAcinetobacter baumanniistrain Serdang 1 in a packed-bed column reactor

2015 ◽  
Vol 57 (28) ◽  
pp. 13307-13317 ◽  
Author(s):  
Z.H.M. Yadzir ◽  
M.Y. Shukor ◽  
A. Ahmad ◽  
M.S. Nazir ◽  
S.M.U. Shah ◽  
...  
Keyword(s):  
Packed Bed ◽  
Phenol Removal ◽  
Packed Bed Column ◽  
Column Reactor

scholarly journals Modeling and Optimization of Carbon Dioxide Removal in Packed Bed Column Reactor

2020 ◽  
Vol 8 (3) ◽  
pp. 8-13
Author(s):  
K. Thirugnanasambandham
Keyword(s):  
Carbon Dioxide ◽  
Process Parameters ◽  
Flow Rate ◽  
Co2 Capture ◽  
Packed Bed ◽  
Operating Conditions ◽  
Feed Flow Rate ◽  
Statistical Design Of Experiments ◽  
Packed Bed Column ◽  
Column Reactor

Global warming due to greenhouse gases has become a serious global issue. Extensive efforts are being made to fighting this phenomenon through carbon capture as carbon dioxide (CO2) is its major contributor. This study focused on CO2 capture in packed bed column reactor using Poly-(D) glucosamine under the various process parameters such as temperature, feed flow rate and mass of the adsorbent. Statistical design of experiments was carried out in order to analysis the effect process parameters on the capacity of CO2 capture in packed bed column. The obtained results show that feed flow rate has the significant affect compared to others. The maximum of 956 mg of CO2 is captured under the following operating conditions; temperature of 40oC, feed flow rate of 30 ml/min and 0.25 g of the Poly-(D) glucosamine. The ability of Poly-(D) glucosamine to capture the CO2 in packed bed column is confirmed.

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