Effects of formulations of the fungicide, pentachloronitrobenzene on early life stage development of the Japanese medaka (Oryzias latipes)

Chemosphere ◽  
2008 ◽  
Vol 71 (10) ◽  
pp. 1957-1962 ◽  
Author(s):  
T.L. Metcalfe ◽  
P.J. Dillon ◽  
C.D. Metcalfe
Keyword(s):  
Early Life ◽  
Life Stage ◽  
Oryzias Latipes ◽  
Early Life Stage ◽  
Japanese Medaka ◽  
Stage Development ◽  
Life Stage Development

scholarly journals Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Megan M. Knuth ◽  
Debabrata Mahapatra ◽  
Dereje Jima ◽  
Debin Wan ◽  
Bruce D. Hammock ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Early Life ◽  
Life Stage ◽  
Somatic Growth ◽  
Early Life Stage ◽  
Cytokine Signaling ◽  
Central Adiposity ◽  
Stage Development ◽  
Life Stage Development

Abstract Emerging evidence demonstrates the importance of sufficient vitamin D (1α, 25-dihydroxyvitamin D3) levels during early life stage development with deficiencies associated with long-term effects into adulthood. While vitamin D has traditionally been associated with mineral ion homeostasis, accumulating evidence suggests non-calcemic roles for vitamin D including metabolic homeostasis. In this study, we examined the hypothesis that vitamin D deficiency (VDD) during early life stage development precedes metabolic disruption. Three dietary cohorts of zebrafish were placed on engineered diets including a standard laboratory control diet, a vitamin D null diet, and a vitamin D enriched diet. Zebrafish grown on a vitamin D null diet between 2–12 months post fertilization (mpf) exhibited diminished somatic growth and enhanced central adiposity associated with accumulation and enlargement of visceral and subcutaneous adipose depots indicative of both adipocyte hypertrophy and hyperplasia. VDD zebrafish exhibited elevated hepatic triglycerides, attenuated plasma free fatty acids and attenuated lipoprotein lipase activity consistent with hallmarks of dyslipidemia. VDD induced dysregulation of gene networks associated with growth hormone and insulin signaling, including induction of suppressor of cytokine signaling. These findings indicate that early developmental VDD impacts metabolic health by disrupting the balance between somatic growth and adipose accumulation.

EFFECT OF BISPHENOL A ON THE EARLY LIFE STAGE IN JAPANESE MEDAKA (ORYZIAS LATIPES)

2000 ◽  
Vol 19 (7) ◽  
pp. 1925 ◽  
Author(s):  
Hirofumi Yokota ◽  
Yukinari Tsuruda ◽  
Masanobu Maeda ◽  
Yuji Oshima ◽  
Hiroshi Tadokoro ◽  
...  
Keyword(s):  
Bisphenol A ◽  
Early Life ◽  
Life Stage ◽  
Oryzias Latipes ◽  
Early Life Stage ◽  
Japanese Medaka

Effects of trilostane and fipronil on the reproductive axis in an early life stage of the Japanese medaka (Oryzias latipes)

Ecotoxicology ◽  
2014 ◽  
Vol 23 (6) ◽  
pp. 1044-1054 ◽  
Author(s):  
Liwei Sun ◽  
Rong Jin ◽  
Zuhua Peng ◽  
Qiwei Zhou ◽  
Haifeng Qian ◽  
...  
Keyword(s):  
Early Life ◽  
Life Stage ◽  
Oryzias Latipes ◽  
Early Life Stage ◽  
Japanese Medaka ◽  
Reproductive Axis

scholarly journals Toxicity implications for early life stage Japanese medaka (Oryzias latipes ) exposed to oxyfluorfen

2018 ◽  
Vol 33 (5) ◽  
pp. 555-568 ◽  
Author(s):  
Doris K. Powe ◽  
Asok K. Dasmahapatra ◽  
Joseph L. Russell ◽  
Paul B. Tchounwou
Keyword(s):  
Early Life ◽  
Life Stage ◽  
Oryzias Latipes ◽  
Early Life Stage ◽  
Japanese Medaka
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