Does time difference of the acetylcholinesterase (AChE) inhibition in different tissues exist? A case study of zebra fish (Danio rerio) exposed to cadmium chloride and deltamethrin

Chemosphere ◽  
2017 ◽  
Vol 168 ◽  
pp. 908-916 ◽  
Author(s):  
Tingting Zhang ◽  
Meiyi Yang ◽  
Hongwei Pan ◽  
Shangge Li ◽  
Baigang Ren ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Qing Ren ◽  
Tingting Zhang ◽  
Shangge Li ◽  
Zongming Ren ◽  
Meiyi Yang ◽  
...  

In order to characterize the toxic response of zebra fish (Danio rerio) to Deltamethrin (DM), behavior strength (BS) and muscle AChE activity of zebra fish were investigated. The results showed that the average values of both BS and AChE activity showed a similarly decreased tendency as DM concentration increased, which confirmed the dose-effect relationship, and high and low levels of AChE and BS partly matched low and high levels of exposure concentrations in self-organizing map. These indicated that AChE and BS had slight different aspects of toxicity although overall trend was similar. Behavior activity suggested a possibility of reviving circadian rhythm in test organisms after exposure to the chemical in lower concentration (0.1 TU). This type of rhythm disappeared in higher concentrations (1.0 TU and 2.0 TU). Time series trend analysis of BS and AChE showed an evident time delayed effect of AChE, and a 2 h AChE inhibition delay with higher correlation coefficients (r) in different treatments was observed. It was confirmed that muscle AChE inhibition of zebra fish is a factor for swimming behavior change, though there was a 2 h delay, and other factors should be investigated to illustrate the detailed behavior response mechanism.


2017 ◽  
Vol 191 ◽  
pp. 236-244 ◽  
Author(s):  
Na Xing ◽  
Lizhen Ji ◽  
Jie Song ◽  
Jingchun Ma ◽  
Shangge Li ◽  
...  

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (09) ◽  
pp. 58-60
Author(s):  
P Samuel ◽  
◽  
B Pavithra ◽  
R. Priyadarshini ◽  
V. Maheswari ◽  
...  

In a pilot scale study, silver and copper nanoparticles were synthesized from two different plant sources viz Flacourtia indica and Prosopsis juliflora. The in vivo toxicity of silver and copper nanoparticles was tested on Danio rerio (Zebra fish) under different concentrations (1 ppm, 10 ppm and 100 ppm). Through the investigation, the nanoparticles treated fishes developed with hyper pigmentation in the ventral region. The minimum lethal concentration required to bring lethality caused by silver nanoparticle was 10 ppm whereas for copper nanoparticles it was 1 ppm. Further, the concentration of silver and copper nanoparticles accumulated inside the fish was evaluated by Atomic Absorption Spectroscopy. The in vivo concentration of silver and copper nanoparticles steadily increases with increase in dosage of nanoparticles being tested.


Fisheries ◽  
2020 ◽  
Vol 2020 (1) ◽  
pp. 66-70
Author(s):  
Yuri Simakov ◽  
Dmitry Nikiforov-Nikishin ◽  
Larisa Bychkova ◽  
Nadegda Lyubovskaya

The results of laboratory experiments on nitroglycerine toxicity detected by histological and cytological indices are presented, using Danio rerio as a case study. For the first time, there are shown the changes in liver and kidneys, both at tissular and cellular levels, induced by administered concentrations of nitroglycerine. The results obtained appear to be important for water bodies’ preservation and elaboration of MPC standards. The intake of nitroglycerine into water bodies is due, mainly, to discharge from pharmaceutical enterprises, demolition works, and outflow from explosives storehouses. Fish turned out to be sensitive to nitroglycerine as indicated by histological and hematological indices. Maximum permissible concentration, MPC, for Danio rerio is determined to be equal to 0.5 mg/l.


Heliyon ◽  
2020 ◽  
Vol 6 (11) ◽  
pp. e05379
Author(s):  
Jayanta Chowdhury ◽  
Tapan Kumar Mandal ◽  
Sandhimita Mondal

2017 ◽  
Vol 44 (2) ◽  
pp. 209-218 ◽  
Author(s):  
Md Golam Rabbane ◽  
Md Mizanur Rahman ◽  
Md Mizanur Rahman ◽  
Md Anwar Hossain ◽  
Md Anwar Hossain

The effect of stocking density on growth of zebra fish was examined. Total five different stocking densities (5, 15, 25, 35 and 45 individuals per 2 liters of water) were maintained in triplicate for a period of 60 days. One month old zebrafish were randomly stocked into 15 tanks and fish were fed with commercial diet. The mean weight gain, specific growth rate and length gain for treatment 1 (5 fish/2liter) and treatment 2 (15 fish/2 liter) were significantly (p < 0.05) higher than treatment 3 (25 fish/2 liter), treatment 4 (35 fish/2 liter) and treatment 5 (45 fish/2 liter). The gender weight gain, survival rate and condition factor did not show any significant (p > 0.05) difference among treatments. The result of this study suggests that the stocking density of zebrafish could be 15 fish per 2 litre of water in a laboratory system with aeration.Bangladesh J. Zool. 44(2): 209-218, 2016


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