Microablative Fractional CO2 Laser for Vulvovaginal Atrophy in women with a history of Breast Cancer: A Pilot Study at Four Week Follow Up

Author(s):  
Stefano Salvatore ◽  
Rossella E. Nappi ◽  
Arianna Casiraghi ◽  
Alessandro F. Ruffolo ◽  
Rebecca Degliuomini ◽  
...  
Author(s):  
Zinat Ghanbari ◽  
Samira Sohbati ◽  
Tahereh Eftekhar ◽  
Leyla Sahebi ◽  
Soodabeh Darvish ◽  
...  

Objective: The aim of this study was to evaluate the safety and efficacy of fractional CO2 laser for treatment of vulvovaginal atrophy. Materials and methods: In this clinical trial study, we evaluated the laser effect on vulvovaginal atrophy in 47 women aged 43-80 years. Each woman was treated with fractional CO2 laser, SmartXide2V2LR, DEKA, Monalisa Touch, vaginal 360o probe and cosmetic probe. The severity of vulvovaginal atrophy symptoms was evaluated before first session of laser and every 4 weeks after laser treatment until 12 weeks. Adverse effects including pain and itching were assessed at all visits. The statistical analysis was performed using SPSS version 23. Results: The response to laser therapy for vaginal dryness was significantly (p <0.001) improved. Also, the response to laser therapy for each symptom include dyspareunia, vaginal discharge, itching and urge urinary incontinence was statistically significant (p <0.001) based on visual analogue scale (VAS). Conclusion: It seems vaginal fractional CO2 laser can be applied as an effective and safe treatment method in genitourinary syndrome of menopause (GSM). It is necessary to conduct studies with long-term follow-up.


2019 ◽  
Vol 178 (1) ◽  
pp. 135-140 ◽  
Author(s):  
Antonia Pearson ◽  
Andrew Booker ◽  
Martin Tio ◽  
Gavin Marx

2014 ◽  
Vol 6 (3) ◽  
pp. 150-156 ◽  
Author(s):  
Stefano Salvatore ◽  
Umberto Leone Roberti Maggiore ◽  
Massimo Origoni ◽  
Marta Parma ◽  
Lavinia Quaranta ◽  
...  

2016 ◽  
Vol 294 (4) ◽  
pp. 841-846 ◽  
Author(s):  
Annalisa Pieralli ◽  
Maria Grazia Fallani ◽  
Angelamaria Becorpi ◽  
Claudia Bianchi ◽  
Serena Corioni ◽  
...  

Menopause ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Allison M. Quick ◽  
Filadelfiya Zvinovski ◽  
Catherine Hudson ◽  
Andrew Hundley ◽  
Cynthia Evans ◽  
...  

Maturitas ◽  
2021 ◽  
Vol 144 ◽  
pp. 37-44
Author(s):  
Allison M. Quick ◽  
Travis Dockter ◽  
Jennifer Le-Rademacher ◽  
Ritu Salani ◽  
Catherine Hudson ◽  
...  

2019 ◽  
Vol 37 (3) ◽  
pp. 164-174 ◽  
Author(s):  
Tae-Hun Kim ◽  
Jung Won Kang

Background: There is an unmet need for effective treatment of the various treatment-related symptoms experienced by breast cancer survivors. These symptoms could be alleviated by acupuncture. Although several lines of evidence in Western countries suggest that acupuncture has a beneficial effect on symptoms in breast cancer survivors, few relevant studies have been conducted in Korean patients. This pilot study assessed the feasibility of acupuncture for a variety of treatment-related symptoms in Korean breast cancer survivors. Method: From October 2015 to March 2016, we recruited patients who had undergone treatment for breast cancer and subsequently reported symptoms, including aromatase inhibitor-related knee pain, vasomotor symptoms, insomnia, sexual dysfunction and post-mastectomy pain in the chest wall or shoulder. The women received 4 weeks of symptom-specific acupuncture followed by a further 4 weeks of follow-up to evaluate the feasibility of acupuncture for this indication, and its impact on common and symptom-specific outcome variables. Results: Eight study participants were recruited over a period of 6 months, six of whom completed the planned acupuncture treatment and follow-up assessments. A total of 78 acupuncture sessions were performed. We found that acupuncture was feasible, with only six minor self-limiting acupuncture-related adverse events. Most of the women felt that they had benefitted from participation in the study. The preliminary analysis indicated improvement in common symptom-specific outcomes. Conclusion: Our findings suggest that acupuncture is feasible, but low recruitment rates should be considered when considering future acupuncture research in Korean breast cancer survivors. Rigorous evaluation of this symptomatic treatment strategy is now needed in the Korean population.


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