Faculty Opinions recommendation of Efficacy of injecting platelet concentrate combined with hyaluronic acid for the treatment of vulvovaginal atrophy in postmenopausal women with history of breast cancer: a phase 2 pilot study.

Author(s):  
Dudley Robinson
Author(s):  
Stefano Salvatore ◽  
Rossella E. Nappi ◽  
Arianna Casiraghi ◽  
Alessandro F. Ruffolo ◽  
Rebecca Degliuomini ◽  
...  

2004 ◽  
Vol 50 (2) ◽  
pp. 161-167 ◽  
Author(s):  
Kathie M. Dalessandri ◽  
Gary L. Firestone ◽  
Mark D. Fitch ◽  
H. Leon Bradlow ◽  
Leonard F. Bjeldanes

2004 ◽  
Vol 89 (3) ◽  
pp. 1207-1212 ◽  
Author(s):  
Eini Nikander ◽  
Merja Metsä-Heikkilä ◽  
Olavi Ylikorkala ◽  
Aila Tiitinen

1996 ◽  
Vol 14 (3) ◽  
pp. 997-1006 ◽  
Author(s):  
J A Roy ◽  
C A Sawka ◽  
K I Pritchard

PURPOSE To review critically the literature regarding effects of estrogen replacement therapy (ERT)/combined estrogen and progesterone replacement therapy (HRT) on the risk of breast cancer and on other health risks and benefits in postmenopausal women, with a focus on risks and benefits in women with a previous diagnosis of breast cancer. METHOD A literature search was conducted using Medline, Cancerline, and the bibliographies of reports published as of March 1995. All five published meta-analyses that examined the risk of breast cancer in relation to ERT/HRT in otherwise healthy women were critically reviewed. All known reports of women with a history of breast cancer given ERT/HRT subsequent to diagnosis and additional reports regarding the benefits of ERT/HRT were also reviewed. RESULTS None of the five meta-analyses demonstrated a significantly increased risk of developing breast cancer in ever users compared with never users of ERT/HRT. Current use may be associated with a small increased risk. This increased risk should be balanced by the expected benefits of ERT/HRT on quality of life, bone metabolism, and cardiovascular function. Preliminary information does not suggest a major detrimental effect of ERT/HRT in women with a previous diagnosis of breast cancer, but these reports include few women with limited follow-up data. There are no randomized trials in women with a previous diagnosis of breast cancer. CONCLUSION In healthy postmenopausal women, the benefits associated with ERT/HRT outweigh the risks. In women with a previous diagnosis of breast cancer, the balance of risks and benefits should be explored in randomized controlled trials.


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