scholarly journals Innate immunity and antimicrobial defense systems in psoriasis

2007 ◽  
Vol 25 (6) ◽  
pp. 616-624 ◽  
Author(s):  
Amanda S. Büchau ◽  
Richard L. Gallo
Keyword(s):  
Innate Immunity ◽  
Antimicrobial Defense ◽  
Defense Systems

Neutrophils and keratinocytes in innate immunity-cooperative actions to provide antimicrobial defense at the right time and place

2004 ◽  
Vol 77 (4) ◽  
pp. 439-443 ◽  
Author(s):  
Niels Borregaard ◽  
Kim Theilgaard-Mönch ◽  
Jack B. Cowland ◽  
Mona Ståhle ◽  
Ole E. Sørensen
Keyword(s):  
Innate Immunity ◽  
Antimicrobial Defense ◽  
The Right

Thromboinflammation as a Driver of Venous Thromboembolism

2021 ◽  
Vol 41 (06) ◽  
pp. 428-432
Author(s):  
Nadine Gauchel ◽  
Krystin Krauel ◽  
Muataz Ali Hamad ◽  
Christoph Bode ◽  
Daniel Duerschmied
Keyword(s):  
Innate Immunity ◽  
Venous Thromboembolism ◽  
Host Defense ◽  
Thrombus Formation ◽  
Pathological Process ◽  
Defense Systems ◽  
Underlying Mechanisms

AbstractThrombus formation has been identified as an integral part in innate immunity, termed immunothrombosis. Activation of host defense systems is known to result in a procoagulant environment. In this system, cellular players as well as soluble mediators interact with each other and their dysregulation can lead to the pathological process of thromboinflammation. These mechanisms have been under intensified investigation during the COVID-19 pandemic. In this review, we focus on the underlying mechanisms leading to thromboinflammation as one trigger of venous thromboembolism.

scholarly journals Testicular defense systems: immune privilege and innate immunity

2014 ◽  
Vol 11 (5) ◽  
pp. 428-437 ◽  
Author(s):  
Shutao Zhao ◽  
Weiwei Zhu ◽  
Shepu Xue ◽  
Daishu Han
Keyword(s):  
Innate Immunity ◽  
Immune Privilege ◽  
Defense Systems

scholarly journals The Linguistics of Bacterial Conflict Systems Reveal Ancient Origins of Eukaryotic Innate Immunity

2020 ◽  
Vol 202 (24) ◽  
Author(s):  
Emily M. Kibby ◽  
Aaron T. Whiteley
Keyword(s):  
Innate Immunity ◽  
Gene Transfer ◽  
Horizontal Gene Transfer ◽  
Evolutionary History ◽  
Protein Domains ◽  
Arms Race ◽  
Bacterial Populations ◽  
Defense Systems ◽  
History Of ◽  
Novel Protein

ABSTRACT The arms race between bacteria and their competitors has produced an astounding variety of conflict systems that are shared via horizontal gene transfer across bacterial populations. In this issue of the Journal of Bacteriology, Burroughs and Aravind investigate how these biological conflict systems have been mixed and matched into new configurations, often with novel protein domains (A. M. Burroughs and L. Aravind, J Bacteriol 202:e00365-20, 2020, https://doi.org/10.1128/JB.00365-20). The authors additionally characterize the evolutionary history of genes in eukaryotes that appear to have been acquired from these prokaryotic defense systems.

Innate immunity, the constant gardener of antimicrobial defense

2013 ◽  
Vol 16 (3) ◽  
pp. 293-295 ◽  
Author(s):  
Kate Schroder ◽  
Vojo Deretic
Keyword(s):  
Innate Immunity ◽  
Antimicrobial Defense

Antimicrobial Defense Systems in Saliva

2014 ◽  
pp. 40-51 ◽  
Author(s):  
Wim van ‘t Hof ◽  
Enno C.I. Veerman ◽  
Arie V. Nieuw Amerongen ◽  
Antoon J.M. Ligtenberg
Keyword(s):  
Antimicrobial Defense ◽  
Defense Systems

scholarly journals Cholangiopathy with Respect to Biliary Innate Immunity

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Kenichi Harada ◽  
Yasuni Nakanuma
Keyword(s):  
Innate Immunity ◽  
Epithelial Mesenchymal Transition ◽  
Biliary Tree ◽  
Biliary Cirrhosis ◽  
Biliary Disease ◽  
Double Stranded Rna ◽  
Mesenchymal Transition ◽  
Defense Systems ◽  
Cytokine Milieu ◽  
Molecular Patterns

Biliary innate immunity is involved in the pathogenesis of cholangiopathies in cases of biliary disease. Cholangiocytes possess Toll-like receptors (TLRs) which recognize pathogen-associated molecular patterns (PAMPs) and play a pivotal role in the innate immune response. Tolerance to bacterial PAMPs such as lipopolysaccharides is also important to maintain homeostasis in the biliary tree, but tolerance to double-stranded RNA (dsRNA) is not found. Moreover, in primary biliary cirrhosis (PBC) and biliary atresia, biliary innate immunity is closely associated with the dysregulation of the periductal cytokine milieu and the induction of biliary apoptosis and epithelial-mesenchymal transition (EMT), forming in disease-specific cholangiopathy. Biliary innate immunity is associated with the pathogenesis of various cholangiopathies in biliary diseases as well as biliary defense systems.

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