13. Development of a functional mapping method using focal cortical cooling in awake craniotomy

2012 ◽  
Vol 123 (9) ◽  
pp. e90
Author(s):  
Masami Fujii ◽  
Takao Inoue ◽  
Hirokazu Sadahiro ◽  
Koji Yoshikawa ◽  
Makoto Ideguchi ◽  
...  
Keyword(s):  
Mapping Method ◽  
Functional Mapping ◽  
Awake Craniotomy ◽  
Cortical Cooling

Matrix Nanodevice-Based Logic Architectures and Associated Functional Mapping Method

2011 ◽  
Vol 7 (1) ◽  
pp. 1-23 ◽  
Author(s):  
P.-E. Gaillardon ◽  
F. Clermidy ◽  
I. O’Connor ◽  
J. Liu ◽  
M. Amadou ◽  
...  
Keyword(s):  
Mapping Method ◽  
Functional Mapping

scholarly journals A focal brain-cooling device as an alternative to electrical stimulation for language mapping during awake craniotomy: patient series

2021 ◽  
Vol 2 (2) ◽  
Author(s):  
Sadahiro Nomura ◽  
Takao Inoue ◽  
Hirochika Imoto ◽  
Hirokazu Sadahiro ◽  
Kazutaka Sugimoto ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Functional Mapping ◽  
Awake Craniotomy ◽  
Mapping Technique ◽  
Broca’S Area ◽  
Brain Cooling ◽  
Broca's Area ◽  
Cooling Device ◽  
Language Mapping ◽  
Patient Series

BACKGROUND Functional mapping in awake craniotomy has the potential risk of electrical stimulation-related seizure. The authors have developed a novel mapping technique using a brain-cooling device. The cooling probe is cylindrical in shape with a thermoelectric cooling plate (10 × 10 mm) at the bottom. A proportional integration and differentiation-controlled system adjusts the temperature accurately (Japan patent no. P5688666). The authors used it in two patients with glioblastoma. Broca’s area was identified by electrical stimulation, and then the cooling probe set at 5°C was attempted on it. OBSERVATIONS Electrocorticogram was suppressed, and the temperature dropped to 8°C in 50 sec. A positive aphasic reaction was reproduced on Broca’s area at a latency of 7 sec. A negative reaction appeared on the adjacent cortices despite the temperature decrease. The sensitivity and specificity were 60% and 100%, respectively. No seizures or other adverse events related to the cooling were recognized, and no histological damage to the cooled cortex was observed. LESSONS The cooling probe suppressed topographical brain function selectively and reversibly. Awake functional mapping based on thermal neuromodulation technology could substitute or compensate for the conventional electrical mapping.

scholarly journals Functional mapping of language-related areas from natural, narrative speech during awake craniotomy surgery

NeuroImage ◽  
2021 ◽  
pp. 118720
Author(s):  
Tianyi Zhou ◽  
Tao Yu ◽  
Zheng Li ◽  
Xiaoxia Zhou ◽  
Jianbin Wen ◽  
...  
Keyword(s):  
Functional Mapping ◽  
Awake Craniotomy

scholarly journals The improvement of museum information flow based on paste functional mapping method

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Haijie Li ◽  
Wenjun Ouyang ◽  
Mohammed Alaa Alhamami
Keyword(s):  
Rapid Development ◽  
Innovation System ◽  
Mapping Method ◽  
Information Resources ◽  
Functional Mapping ◽  
Test Analysis ◽  
Standard Data ◽  
Management Platform ◽  
Lateral Connection ◽  
Innovative Thinking

Abstract As a subsidiary institution of collecting and preserving cultural relics, human cultural heritages and developing information resources, museums are important places to display, disseminate and study excellent national cultures. With the development of the economy and the improvement of people's living standards, people's demand for spiritual culture is getting higher and higher, and museums are getting more and more attention from people. Thanks to the rapid development of computer technology, more and more museums are focusing on informatisation. This article will use the information system's functional mapping method based on the museum's improvement and test analysis, which can make the museum's business unit with the use of the unified system platform, under a unified, homogeneous standard data for the orderly organisation of information resources sharing and efficient, rapid building of information resources of lateral connection, make the administrative, business interaction and interrelated information collection with Word Perfect data integration, and create a museum management platform more conducive to innovative thinking. The innovation system mechanism, to improve the way of ZhanChen for the museum, to speed up the informatisation construction museum, make a museum of play to better spread knowledge, transfer civilisation, materialisation of education function and the important window displaying the world the outstanding civilisation achievement effect, and promote the development of cultural undertakings, where science has a very important realistic and far-reaching historical significance.

scholarly journals SURG-09. EXTRAOPERATIVE CORTICAL MAPPING VIA IMPLANTED SUBDURAL AND DEPTH ELECTRODES FOR MAXIMIZING ELOQUENT AREA GLIOMA RESECTION

2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii205-ii205
Author(s):  
Konstantinos Fountas ◽  
Thanasis Paschalis ◽  
Eftychia Kapsalaki
Keyword(s):  
Extent Of Resection ◽  
Mapping Method ◽  
Awake Craniotomy ◽  
Cortical Mapping ◽  
Depth Electrodes ◽  
Csf Leakage ◽  
Subcortical Stimulation ◽  
The Mean ◽  
Glioma Resection ◽  
Alternative Mapping

Abstract OBJECTIVE Aggressive, even supramarginal, resection without compromising the neurological status of the patient remains a great challenge in the management of glioma cases. Accurate cortical and subcortical functional mapping allows more radical glioma resection. Numerous imaging, electrophysiological, and hybrid methodologies have been employed in the cortical mapping of patients with gliomas in eloquent areas. Despite the recent advances of these non-invasive modalities, direct electrical cortical and subcortical stimulation and mapping through an awake craniotomy remains the gold standard for maximal glioma resection and preservation of eloquent cortex functions. Extraoperative stimulation and mapping via implanted subdural and/or depth electrodes may be a valid alternative mapping method in these cases that an awake procedure is not feasible. The role of this mapping method is examined in our current study. MATERIAL & METHODS In a retrospective study, 51 patients undergoing extraoperative stimulation and mapping for glioma resection were included. The demographic data, the clinical characteristics, the stimulation parameters and complications, the extent of resection, the perioperative complications, and the tumor histological grade were analyzed. Shapiro-Wilk test, as well as uni- and multi-variate regression analysis was used for our statistical analysis. RESULTS The mean age of our participants was 58 (SD: 9.4) years. The location of the glioma was on the left side in 80.4%, while the frontal lobe was affected in 51.0%. Extraoperative cortical and subcortical stimulation and mapping was successful in 94.1%. The median stimulation procedure was 2.0 hours, while the median implantation time was 72 hours. Stimulation-induced seizures occurred in 13.7%, while CSF leakage in 5.9% of our cases. The mean extent of resection was 91.6%, while transient dysphasia occurred in 21.6%, and transient hemiparesis in 5.9% of our cases. CONCLUSIONS Extraoperative stimulation and mapping constitutes a valid alternative mapping option in glioma patients, who cannot undergo an awake craniotomy.

Detection, Averaging, and 3D Reconstruction of Biological Specimens on Hypercubes (Transputer-based) Computers

1990 ◽  
Vol 48 (1) ◽  
pp. 454-455
Author(s):  
Jose-Maria Carazo ◽  
I. Benavides ◽  
S. Marco ◽  
J.L. Carrascosa ◽  
E.L. Zapata
Keyword(s):  
3D Reconstruction ◽  
3D Structure ◽  
Three Dimensional ◽  
Software Tools ◽  
Mapping Method ◽  
Computer Architectures ◽  
Parallel Computer ◽  
Reconstruction Process ◽  
Computing Power ◽  
Order Of Magnitude

Obtaining the three-dimensional (3D) structure of negatively stained biological specimens at a resolution of, typically, 2 - 4 nm is becoming a relatively common practice in an increasing number of laboratories. A combination of new conceptual approaches, new software tools, and faster computers have made this situation possible. However, all these 3D reconstruction processes are quite computer intensive, and the middle term future is full of suggestions entailing an even greater need of computing power. Up to now all published 3D reconstructions in this field have been performed on conventional (sequential) computers, but it is a fact that new parallel computer architectures represent the potential of order-of-magnitude increases in computing power and should, therefore, be considered for their possible application in the most computing intensive tasks.We have studied both shared-memory-based computer architectures, like the BBN Butterfly, and local-memory-based architectures, mainly hypercubes implemented on transputers, where we have used the algorithmic mapping method proposed by Zapata el at. In this work we have developed the basic software tools needed to obtain a 3D reconstruction from non-crystalline specimens (“single particles”) using the so-called Random Conical Tilt Series Method. We start from a pair of images presenting the same field, first tilted (by ≃55°) and then untilted. It is then assumed that we can supply the system with the image of the particle we are looking for (ideally, a 2D average from a previous study) and with a matrix describing the geometrical relationships between the tilted and untilted fields (this step is now accomplished by interactively marking a few pairs of corresponding features in the two fields). From here on the 3D reconstruction process may be run automatically.

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