scholarly journals Reply to “Digging deeper on the neurophysiological assessment in COVID-19 patients”

Author(s):  
Sajid Hameed ◽  
Sara Khan
Author(s):  
Gemma T. Wallace ◽  
Anna R. Docherty

Psychosis spectrum disorders (PSDs) are complex, highly heritable psychiatric conditions with high economic and societal costs. PSDs have historically been conceptualized as neurocognitive disorders in which psychotic episodes and impairments in social and emotional functioning are attributed to deficits in neurocognition. Although cognitive pathways play an important role in the etiology and presentation of PSDs, recent research suggests that interrelations between cognition and emotion are highly relevant. Moreover, aberrant emotion regulation likely plays a significant role in the presentation of PSDs. Emotion dysregulation (ED) may underlie and exacerbate both negative and positive symptoms in PSDs, such as blunted affect, avolition, disorganized speech and behavior, poor social cognition, and delusions and hallucinations. Advances in measurement of emotion dysregulation—including self-reports, behavioral paradigms, neuroimaging paradigms, and neurophysiological assessment—have informed etiological models of emotion dysregulation in PSDs. This chapter reviews research on emotion regulation and dysregulation in PSDs. Notably, more severe presentations of emotion symptoms and greater emotion regulation impairments are associated with worse outcomes in PSDs. It may therefore be the case that focusing on ED as an early risk factor and intervention target could improve outcomes and prevention approaches for psychotic disorders.


1998 ◽  
Vol 21 (2) ◽  
pp. 264-265 ◽  
Author(s):  
Luca Padua ◽  
Mauro LoMonaco ◽  
Bruno Gregori ◽  
Vincenzo Di Lazzaro ◽  
Roberto Padua ◽  
...  

2016 ◽  
pp. 502-536
Author(s):  
Devon I. Rubin ◽  
Jasper R. Daube

Clinical neurophysiology testing primarily assesses and characterizes neurological disease. Selection of appropriate studies for the problem of an individual patient requires a careful clinical evaluation to determine possible causes of the patient’s symptoms. The approach to testing can be assisted by deciding which structures are likely to be involved. For example, motor and sensory symptoms are best assessed using the different methods of motor and sensory NCS. Deciding which neurophysiological measures to apply in peripheral disorders is sometimes assisted by applying guideline protocols based on the patient’s clinical findings and what is found during testing. Although a clinical neurophysiological assessment rarely provides evidence for a specific diagnosis, it can provide valuable information about the severity, progression, and prognosis of the disease. This chapter reviews the clinical application of neurophysiological tests, particularly nerve conduction studies and needle EMG, in the assessment of patients with a variety of neuromuscular complaints.


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