Long-Term Complete Responses to Combination Therapies and Allogeneic Stem Cell Transplants in Patients With Sézary Syndrome

2015 ◽  
Vol 15 (5) ◽  
pp. e83-e93 ◽  
Author(s):  
Maxim Polansky ◽  
Rakhshandra Talpur ◽  
Seema Daulat ◽  
Chitra Hosing ◽  
Bouthaina Dabaja ◽  
...  
2015 ◽  
Vol 15 ◽  
pp. S227-S228
Author(s):  
Maxim Polansky ◽  
Seema Daulat ◽  
Rakhshandra Talpur ◽  
Chitra Hosing ◽  
Bouthaina Dabaja ◽  
...  

2018 ◽  
Vol 10 (3) ◽  
Author(s):  
Hiroki Hosoi ◽  
Kazuo Hatanaka ◽  
Shogo Murata ◽  
Toshiki Mushino ◽  
Kodai Kuriyama ◽  
...  

Sezary syndrome (SS) is a leukemic form of cutaneous T-cell lymphoma and is chemo-resistant. Allogeneic hematopoietic stem cell transplantation is a promising therapy for SS; however, relapse is common. Therapeutic options after relapse have not been established. We managed an SS patient with hematological relapse within one month after transplantation. After discontinuation of immunosuppressants, she achieved complete remission and remained relapse-free. The chimeric analyses of Tcells showed that the full recipient type became complete donor chimera after immunological symptoms. This clinical course suggested that discontinuation of immunosuppressants may result in a graftversus- tumor effect, leading to the eradication of lymphoma cells.


2005 ◽  
Vol 3 ◽  
pp. S105
Author(s):  
Paolo Rama ◽  
Stefano Bonini ◽  
Alessandro Lambiase ◽  
Graziella Pellegrini ◽  
Michele De Luca

2007 ◽  
Vol 39 (6) ◽  
pp. 341-346 ◽  
Author(s):  
A Bacigalupo ◽  
T Lamparelli ◽  
F Gualandi ◽  
D Occhini ◽  
S Bregante ◽  
...  

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