Diagnosing Lymphoproliferative Disorders Using Core Needle Biopsy Versus Surgical Excisional Biopsy: Three-Year Experience of a Reference Center in Lebanon

2020 ◽  
Vol 20 (8) ◽  
pp. e455-e460
Author(s):  
Nada Assaf ◽  
Samer Nassif ◽  
Hani Tamim ◽  
Ali Bazarbachi ◽  
Ghazi Zaatari ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Excisional Biopsy ◽  
Lymphoproliferative Disorders ◽  
Core Needle ◽  
Reference Center

scholarly journals Percutaneous Core Needle Biopsy Can Efficiently and Safely Diagnose Most Primary Bone Tumors

Diagnostics ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 1552
Author(s):  
Vincent Crenn ◽  
Léonard Vezole ◽  
Amine Bouhamama ◽  
Alexandra Meurgey ◽  
Marie Karanian ◽  
...  
Keyword(s):  
Complication Rate ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Bone Tumors ◽  
First Line ◽  
Surgical Biopsy ◽  
Core Needle ◽  
Reference Center ◽  
Referral Center ◽  
Percutaneous Core Needle Biopsy

A biopsy is a prerequisite for the diagnosis and evaluation of musculoskeletal tumors. It is considered that surgical biopsy provides a more reliable diagnosis because it can obtain more tumor material for pathological analysis. However, it is often associated with a significant complication rate. Imaging-guided percutaneous core needle biopsy (PCNB) is now widely used as an alternative to surgical biopsy; it appears to be minimally invasive, possibly with lower complication rates. This study evaluates the diagnostic yield of the preferred use of PCNB in a referral center, its accuracy, and its complication rate. The data relating to the biopsy and the histological analysis were extracted from the database of a bone tumor reference center where PCNB of bone tumors was discussed as a first-line option. 196 bone tumors were biopsied percutaneously between 2016 and 2020. They were located in the axial skeleton in 21.4% (42) of cases, in the lower limb in 58.7% (115), and in the upper limb in 19.9% (39) cases. We obtained a diagnosis yield of 84.7% and a diagnosis accuracy of 91.7%. The overall complication rate of the percutaneous biopsies observed was 1.0% (n = 2), consisting of two hematomas. PCNB performed in a referral center is a safe, precise procedure, with a very low complication rate, and which avoids the need for first-line open surgical biopsy. The consultation between pathologist, radiologist, and clinician in an expert reference center makes this technique an effective choice as a first-line diagnosis tool.

Lobular In-Situ Neoplasia on Breast Core Needle Biopsy: Imaging Indication and Pathologic Extent Can Identify Which Patients Require Excisional Biopsy

2011 ◽  
Vol 19 (3) ◽  
pp. 914-921 ◽  
Author(s):  
Mara H. Rendi ◽  
Suzanne M. Dintzis ◽  
Constance D. Lehman ◽  
Kristine E. Calhoun ◽  
Kimberly H. Allison
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Excisional Biopsy ◽  
Core Needle

Role of image-guided core-needle biopsy in the management of patients with lymphoma.

1996 ◽  
Vol 14 (9) ◽  
pp. 2427-2430 ◽  
Author(s):  
V I Pappa ◽  
H K Hussain ◽  
R H Reznek ◽  
J Whelan ◽  
A J Norton ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Previous History ◽  
Excisional Biopsy ◽  
Low Grade ◽  
High Grade ◽  
Core Needle ◽  
Image Guided ◽  
Efficient Alternative

PURPOSE The results of 106 radiologically guided core needle biopsies in 96 patients were analyzed retrospectively to evaluate the accuracy, safety, and role of this technique in the management of patients with lymphoma and to determine factors predictive of success. PATIENTS AND METHODS Biopsies were performed in 51 patients with low-grade non-Hodgkin's lymphoma (NHL), 24 with high-grade NHL, 16 with previously diagnosed Hodgkin's disease (HD), and 15 with no previous history of lymphoma. Disease was infradiaphragmatic in 92 patients and supradiaphragmatic in 14. Computed tomography (CT) guidance was used in 98 biopsies and ultrasonography (US) in eight. RESULTS The biopsy was diagnostic and yielded information on the basis of which treatment was started in 88 of 106 patients. The procedure was well tolerated and there were no major complications. Small size of the sample or inappropriate tissue sampled were the main causes of failure. The technique was equally successful in the diagnosis of HD and both high-grade and low-grade NHL as in nonlymphoproliferative disorders. The procedure was equally successful at diagnosis as at suspected recurrence or progression. In 33 of 80 cases in which the biopsy was performed at the time of recurrence or progression, the histology had changed; in 31 of 33, this influenced treatment. The technique was efficient at diagnosing transformation of follicular NHL in 16 of 18 patients, which allowed early adjustment of treatment at recurrence. CONCLUSION At St Bartholomew's Hospital (SBH), image-guided core-needle biopsy has proven to be a quick, safe, and efficient alternative to excisional biopsy in the evaluation of lymphoproliferative disorders at presentation, recurrence, or progression. It should become the procedure of choice for histologic sampling in the absence of peripheral lymphadenopathy.

scholarly journals Atypical papillary lesions after core needle biopsy and subsequent breast carcinoma

2011 ◽  
Vol 5 (2) ◽  
pp. 243-248
Author(s):  
Tuenchit Khamapirad ◽  
Caitlin Andrews ◽  
Jenjeera Prueksadee ◽  
Morton Leonard ◽  
Louisea Bonoan-Deomampo ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Surgical Excision ◽  
Excisional Biopsy ◽  
Papillary Lesion ◽  
Architectural Distortion ◽  
Core Needle ◽  
Multiple Imaging ◽  
Papillary Lesions ◽  
Benign Papilloma

Abstract Background: Papillary lesions of the breast cause diagnostic problem because papillary structures are found in benign and malignant processes. Core needle biopsy is important to make an initial diagnosis, but it still has potential pitfalls. Comparison between core needle biopsy and excisional biopsy can predict the possibility of malignant change in atypical papillary lesions. Objective: Evaluate the concordance between core needle biopsy and excisional results in atypical papillary lesions of the breast. Materials and methods: The pathology database of University of Texas Medical Branch at Galveston, USA was searched for patients with atypical papillary lesions at core needle biopsy who subsequently underwent surgical excision. Pathology reports from the excisional biopsies was also examined to assign each case to one of three categories, downgrade to benign papilloma, no change (remained atypical papillary lesion), and upgrade to carcinoma. The mammograms and ultrasounds were reviewed for each case. They characterized the lesions according to multiple imaging criteria. Results: Twenty-four patients with atypical papillomas at core biopsy subsequently underwent surgical excision. The lesions were downgraded to benign papilloma in 25%, remained atypical papillary lesion in 33%, and upgraded to carcinoma in 42%. On mammographic presentations (n = 23), masses were in 61%, architectural distortion in 4.3%, mass with calcifications in 9%, mass with architectural distortion and calcifications in 4.3%, calcifications alone in 17.4%, and architectural distortion and calcifications in 4.3%. On ultrasound findings (n = 21), solid masses were in 90%, intracystic masses in 10%, peripheral in locations in 81%, and subareolar in location in 19%. Conclusion: Due to the high upgrade rate of atypical papillary lesions to carcinoma (42%), excision of all atypical papillary lesions with wide excision margin is recommended for cases with pathologic diagnosis of atypical papillary lesion on core-needle biopsy.

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