Determinants of hand grip strength, knee extension strength and functional status in cancer patients

2010 ◽  
Vol 29 (5) ◽  
pp. 586-591 ◽  
Author(s):  
Kristina Norman ◽  
Nicole Stobäus ◽  
Christine Smoliner ◽  
Daniela Zocher ◽  
Ramona Scheufele ◽  
...  
Keyword(s):  
Functional Status ◽  
Grip Strength ◽  
Cancer Patients ◽  
Knee Extension ◽  
Hand Grip Strength ◽  
Knee Extension Strength ◽  
Hand Grip

scholarly journals A single-arm feasibility study of community-delivered Baduanjin (Qigong practice of the eight Brocades) training for frail older adults

2020 ◽  
Author(s):  
Xiao Liu ◽  
Jean Wei Ting Seah ◽  
Benedict Wei Jun Pang ◽  
Mary Ann Tsao ◽  
Falong Gu ◽  
...  
Keyword(s):  
Older Adults ◽  
Adverse Events ◽  
Training Program ◽  
Grip Strength ◽  
Fall Risk ◽  
Knee Extension ◽  
Hand Grip Strength ◽  
Frail Older Adults ◽  
Knee Extension Strength ◽  
Hand Grip

Abstract Background: Frailty is a common geriatric syndrome, characterized by reduced physiologic reserve and increased vulnerability to stressors, due to cumulative decline in multiple physiological systems. We studied the feasibility of a community-delivered Baduanjin (BDJ) training program among pre-frail/frail community-dwelling older people. We examined 1) safety (adverse events), physical and psychological effects; and 2) feasibility of recruitment, retention, adherence; recruitment efforts and any program challenges, so as to inform future studies.Methods: Our study was a single arm pre-post study in a community setting. Sixteen week group BDJ training (2x/week in the first 4 weeks, and 3x/week thereafter) co-designed and implemented by community-based providers in Singapore. Recruitment, attendance and adverse events were recorded throughout the training. A participants’ survey was also administered after the training program. Effects of the intervention on physical and functional outcomes (hand grip strength, knee extension strength, Time Up and Go (TUG), Physiological Profile Assessment (PPA), 30-second Sit-to-Stand test, 6-meter fast gait speed test), frailty outcomes (frailty score and status), and other outcomes (Maastricht Questionnaire (MQ), Fall Efficacy Scale (FES), Montreal Cognitive Assessment (MoCA), Geriatric Depression Scale (GDS), and EQ-5D-5L) were examined before and after the program.Results: Of 31 older adults screened to be frail, 15 met inclusion criteria and 3 refused participation, resulting in 12 older adults (9 women) enrolled into the program. During the program, one participant was hospitalized (unrelated to BDJ training) and the other 11 (aged 77±6 years; 2 frail, 9 prefrail at baseline) completed the program with average overall attendance of 89%. Most (89%) of the 44 training sessions had attendance >80%. The program received positive feedback with no training-related adverse events. Participants either reversed (n=2) or maintained (n=9) their frailty statuses. There post-training outcomes in hand grip strength, knee extension strength, TUG , MQ , FES , MoCA , GDS and EQ-5D-5L index score appeared to be better. The reduction of frailty and PPA fall risk scores were of moderate-to-large effect size. Conclusions: Community-delivered BDJ training program was safe and feasible for prefrail/frail older adults with the potential to improve physical and cognitive function, reduce fall risk, improve psychological well-being, and reverse frailty status.

scholarly journals Combination of the G-8 Screening Tool and Hand-Grip Strength to Predict Long-Term Overall Survival in Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3363
Author(s):  
Kristian Kirkelund Bentsen ◽  
Olfred Hansen ◽  
Jesper Ryg ◽  
Ann-Kristine Weber Giger ◽  
Stefan Starup Jeppesen
Keyword(s):  
Overall Survival ◽  
Grip Strength ◽  
Cancer Patients ◽  
Stereotactic Body Radiotherapy ◽  
Statistical Significance ◽  
Multivariable Analysis ◽  
Hand Grip Strength ◽  
Physical Test ◽  
Hand Grip

The Geriatric 8 (G-8) is a known predictor of overall survival (OS) in older cancer patients, but is mainly based on nutritional aspects. This study aimed to assess if the G-8 combined with a hand-grip strength test (HGST) in patients with NSCLC treated with stereotactic body radiotherapy can predict long-term OS better than the G-8 alone. A total of 46 SBRT-treated patients with NSCLC of stage T1-T2N0M0 were included. Patients were divided into three groups: fit (normal G-8 and HGST), vulnerable (abnormal G-8 or HGST), or frail (abnormal G-8 and HGST). Statistically significant differences were found in 4-year OS between the fit, vulnerable, and frail groups (70% vs. 46% vs. 25%, p = 0.04), as well as between the normal and abnormal G-8 groups (69% vs. 39%, p = 0.02). In a multivariable analysis of OS, being vulnerable with a hazard ratio (HR) of 2.03 or frail with an HR of 3.80 indicated poorer OS, but this did not reach statistical significance. This study suggests that there might be a benefit of adding a physical test to the G-8 for more precisely predicting overall survival in SBRT-treated patients with localized NSCLC. However, this should be confirmed in a larger study population.

scholarly journals Correlation between lymphocyte-monocyte ratio and hand grip strength in breast cancer patients before chemotherapy

2018 ◽  
Vol 29 ◽  
pp. ix136
Author(s):  
A. Kurniawan ◽  
R.D. Hatma ◽  
A. Adisasmita ◽  
N. Soetandyo ◽  
F. Witjaksono ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Grip Strength ◽  
Cancer Patients ◽  
Hand Grip Strength ◽  
Breast Cancer Patients ◽  
Hand Grip

scholarly journals Impact of daily protein and energy intake and distribution on muscle mass and strength in Danish older individuals-The CALM study

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Yusuke Nishimura ◽  
Grith Hojfeldt ◽  
Simon Rønnow Schacht ◽  
Kenneth Mertz ◽  
Morten Hjulmand ◽  
...  
Keyword(s):  
Total Energy ◽  
Grip Strength ◽  
Muscle Mass ◽  
Energy Intake ◽  
Protein Intake ◽  
Knee Extension ◽  
Hand Grip Strength ◽  
Energy Ratio ◽  
Older Individuals ◽  
Hand Grip

AbstractThe importance of dietary protein for the maintenance of muscle mass and strength is heavily discussed. However, adequate energy intake is an underlying assumption but often not considered. In this study, we investigated the impact of daily intake and meal distribution of both protein and energy on muscle mass and strength. In a cross-sectional study, a total of 184 older individuals (gender: 86F/98M, age: 70.2 ± 3.9 yrs, BMI: 25.4 ± 3.7 kg/m2; means ± SD) were recruited. Participants underwent a 3-day weighed dietary record, Dual-energy X-ray Absorptiometry (DXA) scan, hand-grip strength, and Maximal Voluntary Isometric knee-extension Contraction (MVIC). Participants were divided into two categories: lower (LOW; < 0.83 g/adjusted(a)BW/day) or higher (HIGH; ≥ 1.1 g/aBW/day) protein intake levels analysed by gender to characterize a daily protein and energy intake pattern. Main meal protein and energy intake distributions were calculated, and correlations were made. Further, energy intake at breakfast and lunch divided by total energy intake (energy ratio) was correlated with appendicular skeletal muscle index (ASMI), hand-grip strength, and MVIC were determined using the LOW/HIGH-protein-intake categorization. Further, gender-specific ASMI, hand-grip strength and knee extension were compared based on the following four distinct daily protein intake ranges: < 0.66; ≥ 0.66- < 0.83; ≥ 0.83- < 1.1; ≥ 1.1 g/aBW/day. A positive correlation appeared between protein and energy intake in all main meals (r ≥ 0.57, p < 0.0001). In the LOW category, positive correlations were found between energy ratio and ASMI (r = 0.16, p = 0.048), hand-grip strength (r = 0.40, p = 0.0009), and MVIC (r = 0.36, p = 0.0019), whereas no associations were found in the HIGH category. ASMI, hand grip, and MVIC were similar regardless of the protein intake ranges, though with women being lower than men (p < 0.05) in all outcomes. These results show that total daily protein intake did not affect muscle mass and strength in our cohort. However, our data demonstrate that greater energy intake in breakfast and lunch relative to total energy intake is associated with higher muscle mass and strength, particularly when protein intake is lower than 0.83 g/aBW/day, indicating the potential importance of meal energy content at lower intakes of protein.

scholarly journals Effects of Resistance Exercise on Muscle Mass, Strength, and Physical Performances in Elderly with Diagnosed Sarcopenia: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 29 (2) ◽  
pp. 109-120
Author(s):  
Kyung Min Kim ◽  
Hyun Joo Kang
Keyword(s):  
Resistance Exercise ◽  
Grip Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Meta Analysis ◽  
Knee Extension ◽  
Timed Up And Go ◽  
Knee Extension Strength ◽  
Hand Grip ◽  
Appendicular Muscle Mass

PURPOSE: Sarcopenia, also known as the age-related loss of muscle mass and muscle fitness, and physical performance, has been related to many adverse health outcomes. Resistance exercise may have an important role in effecting strategy for sarcopenia in aging populations. The purpose of this study is to systematically assess the effects resistance exercise interventions on muscle mass, muscle strength, and physical performance in elderly diagnosed with sarcopenia.METHODS: A comprehensive search on electronic databases, including PubMed, EMBASE, CINAHLPlus, SPORTDiscus, KERIS, KISS, and NAL were conducted. Eligible studies were divided into exercise and randomized controlled trials in elderly with sarcopenia. Searches retrieved 1,067 titles. Eighty full texts were evaluated, and seven studies were used for final systematic reviews. CMA (Comprehensive Meta-Analysis) ver 3.0 was used for meta-analysis.RESULTS: Meta-analysis showed that lower muscle mass (ES=0.579, 95% CI: 0.266-0.892, <i>p</i>=.000), appendicular muscle mass (ES=0.341, 95% CI: 0.006-0.676, <i>p</i>=.046), right hand grip strength (ES=0.739, 95% CI: 0.216-1.262, <i>p</i>=.006), left hand grip strength (ES=0.692, 95% CI: 0.167-1.217, <i>p</i>=.010), knee extension strength (ES=1.448, 95% CI: 0.273-2.624, <i>p</i>=.016), and timed up and go (ES=1.471, 95% CI: 0.492-2.450, <i>p</i>=.003) significantly improved in response to resistance exercise programs.CONCLUSIONS: Sarcopenia is increasing with the growing elderly population; thus prevention and effective interventions are very important. The data suggest that resistance exercise may be actual in enhancing not only appendicular muscle mass, but also knee extension strength and timed up and go in elderly diagnosed with sarcopenia. Further follow-up studies on larger populations and a variety of approaches are required to reconfirm these results.

The Correlation between Hand Grip Strength and Nutritional Variables in Ambulatory Cancer Patients

2020 ◽  
pp. 1-9
Author(s):  
Antonio Augusto Claudio Pereira ◽  
Rebecca Dias Zaia ◽  
Gustavo Henrique Gandolfo Souza ◽  
Bárbara Okabaiasse Luizeti ◽  
Ricardo Andreola ◽  
...  
Keyword(s):  
Grip Strength ◽  
Cancer Patients ◽  
Hand Grip Strength ◽  
Hand Grip

scholarly journals Effects of Resistance Exercise on Muscle Mass, Strength, and Physical Performances in Elderly with Diagnosed Sarcopenia: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 29 (2) ◽  
pp. 109-120 ◽  
Author(s):  
Kyung Min Kim ◽  
Hyun Joo Kang
Keyword(s):  
Resistance Exercise ◽  
Grip Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Meta Analysis ◽  
Knee Extension ◽  
Timed Up And Go ◽  
Knee Extension Strength ◽  
Hand Grip ◽  
Appendicular Muscle Mass

PURPOSE: Sarcopenia, also known as the age-related loss of muscle mass and muscle fitness, and physical performance, has been related to many adverse health outcomes. Resistance exercise may have an important role in effecting strategy for sarcopenia in aging populations. The purpose of this study is to systematically assess the effects resistance exercise interventions on muscle mass, muscle strength, and physical performance in elderly diagnosed with sarcopenia.METHODS: A comprehensive search on electronic databases, including PubMed, EMBASE, CINAHLPlus, SPORTDiscus, KERIS, KISS, and NAL were conducted. Eligible studies were divided into exercise and randomized controlled trials in elderly with sarcopenia. Searches retrieved 1,067 titles. Eighty full texts were evaluated, and seven studies were used for final systematic reviews. CMA (Comprehensive Meta-Analysis) ver 3.0 was used for meta-analysis.RESULTS: Meta-analysis showed that lower muscle mass (ES=0.579, 95% CI: 0.266-0.892, <i>p</i>=.000), appendicular muscle mass (ES=0.341, 95% CI: 0.006-0.676, <i>p</i>=.046), right hand grip strength (ES=0.739, 95% CI: 0.216-1.262, <i>p</i>=.006), left hand grip strength (ES=0.692, 95% CI: 0.167-1.217, <i>p</i>=.010), knee extension strength (ES=1.448, 95% CI: 0.273-2.624, <i>p</i>=.016), and timed up and go (ES=1.471, 95% CI: 0.492-2.450, <i>p</i>=.003) significantly improved in response to resistance exercise programs.CONCLUSIONS: Sarcopenia is increasing with the growing elderly population; thus prevention and effective interventions are very important. The data suggest that resistance exercise may be actual in enhancing not only appendicular muscle mass, but also knee extension strength and timed up and go in elderly diagnosed with sarcopenia. Further follow-up studies on larger populations and a variety of approaches are required to reconfirm these results.

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