scholarly journals Impact of daily protein and energy intake and distribution on muscle mass and strength in Danish older individuals-The CALM study

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Yusuke Nishimura ◽  
Grith Hojfeldt ◽  
Simon Rønnow Schacht ◽  
Kenneth Mertz ◽  
Morten Hjulmand ◽  
...  
Keyword(s):  
Total Energy ◽  
Grip Strength ◽  
Muscle Mass ◽  
Energy Intake ◽  
Protein Intake ◽  
Knee Extension ◽  
Hand Grip Strength ◽  
Energy Ratio ◽  
Older Individuals ◽  
Hand Grip

AbstractThe importance of dietary protein for the maintenance of muscle mass and strength is heavily discussed. However, adequate energy intake is an underlying assumption but often not considered. In this study, we investigated the impact of daily intake and meal distribution of both protein and energy on muscle mass and strength. In a cross-sectional study, a total of 184 older individuals (gender: 86F/98M, age: 70.2 ± 3.9 yrs, BMI: 25.4 ± 3.7 kg/m2; means ± SD) were recruited. Participants underwent a 3-day weighed dietary record, Dual-energy X-ray Absorptiometry (DXA) scan, hand-grip strength, and Maximal Voluntary Isometric knee-extension Contraction (MVIC). Participants were divided into two categories: lower (LOW; < 0.83 g/adjusted(a)BW/day) or higher (HIGH; ≥ 1.1 g/aBW/day) protein intake levels analysed by gender to characterize a daily protein and energy intake pattern. Main meal protein and energy intake distributions were calculated, and correlations were made. Further, energy intake at breakfast and lunch divided by total energy intake (energy ratio) was correlated with appendicular skeletal muscle index (ASMI), hand-grip strength, and MVIC were determined using the LOW/HIGH-protein-intake categorization. Further, gender-specific ASMI, hand-grip strength and knee extension were compared based on the following four distinct daily protein intake ranges: < 0.66; ≥ 0.66- < 0.83; ≥ 0.83- < 1.1; ≥ 1.1 g/aBW/day. A positive correlation appeared between protein and energy intake in all main meals (r ≥ 0.57, p < 0.0001). In the LOW category, positive correlations were found between energy ratio and ASMI (r = 0.16, p = 0.048), hand-grip strength (r = 0.40, p = 0.0009), and MVIC (r = 0.36, p = 0.0019), whereas no associations were found in the HIGH category. ASMI, hand grip, and MVIC were similar regardless of the protein intake ranges, though with women being lower than men (p < 0.05) in all outcomes. These results show that total daily protein intake did not affect muscle mass and strength in our cohort. However, our data demonstrate that greater energy intake in breakfast and lunch relative to total energy intake is associated with higher muscle mass and strength, particularly when protein intake is lower than 0.83 g/aBW/day, indicating the potential importance of meal energy content at lower intakes of protein.

scholarly journals Regular Exercise and Depressive Symptoms in Korean Older Adults

2021 ◽  
Vol 18 (1) ◽  
pp. 303
Author(s):  
Young-Mee Kim ◽  
Sung-il Cho
Keyword(s):  
Depressive Symptoms ◽  
Grip Strength ◽  
Multivariate Logistic Regression Analysis ◽  
Depression Scale ◽  
Epidemiological Studies ◽  
Hand Grip Strength ◽  
Regular Exercise ◽  
Older Individuals ◽  
Related Factors ◽  
Hand Grip

Prior studies have found that exercise has a positive effect on depressive symptoms in the general population. For older individuals, however, the association between exercise and depressive symptoms is conclusive. We examined whether regular exercise is related to depressive symptoms in 5379 Korean adults aged ≥55 years using data from a 2016 survey administered in the Korean Longitudinal Study of Aging. We used the 10-item Center for Epidemiological Studies–Depression scale to assess depressive symptoms. We performed a multivariate logistic regression analysis to investigate the relationship between regular exercise and depressive symptoms, adjusting for sociodemographic characteristics, self-rated health, number of chronic diseases, body mass index, hand-grip strength, physical disability, cognitive impairment, and health behavior. Interaction terms, including regular exercise and health-related factors, were also added. We found that a lack of regular exercise was significantly related to an increased frequency of depressive symptoms (OR = 1.18, 95% CI = 1.03–1.35). Moreover, hand-grip strength may increase the effect of regular exercise on depressive symptoms in individuals 65 years and older (OR = 1.01 vs. 1.70, 95% CI = 1.05–1.96). Our results suggest that it is important to encourage older individuals to exercise regularly as a means of relieving depressive symptoms.

Physical fitness, activity and hand-grip strength are not associated with arterial stiffness in older individuals

2015 ◽  
Vol 19 (7) ◽  
pp. 779-784 ◽  
Author(s):  
S. C. van Dijk ◽  
K. M. A. Swart ◽  
A. C. Ham ◽  
A. W. Enneman ◽  
J. P. van Wijngaarden ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Physical Fitness ◽  
Grip Strength ◽  
Hand Grip Strength ◽  
Older Individuals ◽  
Hand Grip

scholarly journals Lower Percentage of Fat Mass among Tai Chi Chuan Practitioners

2020 ◽  
Vol 17 (4) ◽  
pp. 1232
Author(s):  
Silvia Stagi ◽  
Azzurra Doneddu ◽  
Gabriele Mulliri ◽  
Giovanna Ghiani ◽  
Valeria Succa ◽  
...  
Keyword(s):  
Body Composition ◽  
Grip Strength ◽  
Muscle Mass ◽  
Fat Mass ◽  
Tai Chi ◽  
Hand Grip Strength ◽  
Middle Aged ◽  
Tai Chi Chuan ◽  
Hand Grip ◽  
Total Body

The aim of the study was to analyze total and regional body composition in Tai Chi Chuan (TCC) middle-aged and elderly practitioners. A cross-sectional study on 139 Italian subjects was realized: 34 TCC practitioners (14 men, 20 women; 62.8 ± 7.4 years) and 105 sedentary volunteers (49 men, 56 women; 62.8 ± 6.4 years). Anthropometric measurements (height, weight, arm, waist, and calf circumferences), hand-grip strength, and physical capacity values were collected. Total and regional (arm, leg, and trunk) body composition was analyzed by means of specific bioelectrical impedance vector analysis (specific BIVA). TCC practitioners of both sexes were characterized by a normal nutritional status, normal levels of physical capacity, and normal values of hand-grip strength. Compared to controls, they showed lower percentages of fat mass (lower specific resistance) in the total body, the arm, and the trunk, and higher muscle mass (higher phase angle) in the trunk, but lower muscle mass in the arm. Sexual dimorphism was characterized by higher muscle mass (total body, arm, and trunk) and lower %FM (arm) in men; sex differences were less accentuated among TCC practitioners than in the control. TCC middle-aged and elderly practitioners appear to be less affected by the process of physiological aging and the associated fat mass changes, compared to sedentary people.

scholarly journals A single-arm feasibility study of community-delivered Baduanjin (Qigong practice of the eight Brocades) training for frail older adults

2020 ◽  
Author(s):  
Xiao Liu ◽  
Jean Wei Ting Seah ◽  
Benedict Wei Jun Pang ◽  
Mary Ann Tsao ◽  
Falong Gu ◽  
...  
Keyword(s):  
Older Adults ◽  
Adverse Events ◽  
Training Program ◽  
Grip Strength ◽  
Fall Risk ◽  
Knee Extension ◽  
Hand Grip Strength ◽  
Frail Older Adults ◽  
Knee Extension Strength ◽  
Hand Grip

Abstract Background: Frailty is a common geriatric syndrome, characterized by reduced physiologic reserve and increased vulnerability to stressors, due to cumulative decline in multiple physiological systems. We studied the feasibility of a community-delivered Baduanjin (BDJ) training program among pre-frail/frail community-dwelling older people. We examined 1) safety (adverse events), physical and psychological effects; and 2) feasibility of recruitment, retention, adherence; recruitment efforts and any program challenges, so as to inform future studies.Methods: Our study was a single arm pre-post study in a community setting. Sixteen week group BDJ training (2x/week in the first 4 weeks, and 3x/week thereafter) co-designed and implemented by community-based providers in Singapore. Recruitment, attendance and adverse events were recorded throughout the training. A participants’ survey was also administered after the training program. Effects of the intervention on physical and functional outcomes (hand grip strength, knee extension strength, Time Up and Go (TUG), Physiological Profile Assessment (PPA), 30-second Sit-to-Stand test, 6-meter fast gait speed test), frailty outcomes (frailty score and status), and other outcomes (Maastricht Questionnaire (MQ), Fall Efficacy Scale (FES), Montreal Cognitive Assessment (MoCA), Geriatric Depression Scale (GDS), and EQ-5D-5L) were examined before and after the program.Results: Of 31 older adults screened to be frail, 15 met inclusion criteria and 3 refused participation, resulting in 12 older adults (9 women) enrolled into the program. During the program, one participant was hospitalized (unrelated to BDJ training) and the other 11 (aged 77±6 years; 2 frail, 9 prefrail at baseline) completed the program with average overall attendance of 89%. Most (89%) of the 44 training sessions had attendance >80%. The program received positive feedback with no training-related adverse events. Participants either reversed (n=2) or maintained (n=9) their frailty statuses. There post-training outcomes in hand grip strength, knee extension strength, TUG , MQ , FES , MoCA , GDS and EQ-5D-5L index score appeared to be better. The reduction of frailty and PPA fall risk scores were of moderate-to-large effect size. Conclusions: Community-delivered BDJ training program was safe and feasible for prefrail/frail older adults with the potential to improve physical and cognitive function, reduce fall risk, improve psychological well-being, and reverse frailty status.

Determinants of hand grip strength, knee extension strength and functional status in cancer patients

2010 ◽  
Vol 29 (5) ◽  
pp. 586-591 ◽  
Author(s):  
Kristina Norman ◽  
Nicole Stobäus ◽  
Christine Smoliner ◽  
Daniela Zocher ◽  
Ramona Scheufele ◽  
...  
Keyword(s):  
Functional Status ◽  
Grip Strength ◽  
Cancer Patients ◽  
Knee Extension ◽  
Hand Grip Strength ◽  
Knee Extension Strength ◽  
Hand Grip

scholarly journals Disentangling the Genetics of Sarcopenia: prioritization of NUDT3 and KLF5 as genes for lean mass and HLA-DQB1-AS1 for hand grip strength based on associated SNPs

2019 ◽  
Author(s):  
Abhishek N. Singh
Keyword(s):  
Grip Strength ◽  
Muscle Mass ◽  
Lean Mass ◽  
Musculoskeletal Diseases ◽  
Hand Grip Strength ◽  
Muscle Disease ◽  
P Value ◽  
Hand Grip ◽  
Increased Risk ◽  
Regulatory Snps

Abstract Background: Sarcopenia is a skeletal muscle disease of clinical importance that occurs commonly in old age and in various disease sub-categories. Widening the scope of knowledge of the genetics of muscle mass and strength is important because may allows us to identify new genetic markers or identify patients with an increased risk to develop a specific musculoskeletal diseases or condition such as sarcopenia. It might also allow us to identify drugs that affect muscle in ways unknown before and therefore to reposition drugs to other uses, in accordance to their newly found target. We used bioinformatics tools to identify gene loci responsible for regulating muscle strength and lean muscle mass, which can then be a target for downstream lab experimentation validation. SNPs associated with various disease traits for the muscles and specific loci were chosen according to their muscle phenotype association p-value, as traditionally done in the GWASs. We developed and applied a combination of expression quantitative trait loci study (eQTLs) and GWAS summary information, to prioritize causative SNP and point out the unique genes associated in the tissues of interest (muscle). Results: We found NUDT3 and KLF5 for lean mass and HLA-DQB1-AS1 for hand grip strength as candidate genes to target for these phenotypes. The associated regulatory SNPs are rs464553, rs1028883 and rs3129753 respectively. Conclusion: TWAS approaches of combining GWAS and eQTL summary statistics proved helpful in statistically prioritizing genes and their associated SNPs for the disease phenotype of study, here, Sarcopenia. Potentially regulatory SNPs associated with these genes can be analyzed with respect to TADs and then targeted for knock out in either C2C12 mouse myoblast cells, adipocytes or any other relevant cell, depending on the phenotype it is hypothesized to affect, as a downstream experimental validation plan.

scholarly journals Effects of Resistance Exercise on Muscle Mass, Strength, and Physical Performances in Elderly with Diagnosed Sarcopenia: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 29 (2) ◽  
pp. 109-120
Author(s):  
Kyung Min Kim ◽  
Hyun Joo Kang
Keyword(s):  
Resistance Exercise ◽  
Grip Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Meta Analysis ◽  
Knee Extension ◽  
Timed Up And Go ◽  
Knee Extension Strength ◽  
Hand Grip ◽  
Appendicular Muscle Mass

PURPOSE: Sarcopenia, also known as the age-related loss of muscle mass and muscle fitness, and physical performance, has been related to many adverse health outcomes. Resistance exercise may have an important role in effecting strategy for sarcopenia in aging populations. The purpose of this study is to systematically assess the effects resistance exercise interventions on muscle mass, muscle strength, and physical performance in elderly diagnosed with sarcopenia.METHODS: A comprehensive search on electronic databases, including PubMed, EMBASE, CINAHLPlus, SPORTDiscus, KERIS, KISS, and NAL were conducted. Eligible studies were divided into exercise and randomized controlled trials in elderly with sarcopenia. Searches retrieved 1,067 titles. Eighty full texts were evaluated, and seven studies were used for final systematic reviews. CMA (Comprehensive Meta-Analysis) ver 3.0 was used for meta-analysis.RESULTS: Meta-analysis showed that lower muscle mass (ES=0.579, 95% CI: 0.266-0.892, <i>p</i>=.000), appendicular muscle mass (ES=0.341, 95% CI: 0.006-0.676, <i>p</i>=.046), right hand grip strength (ES=0.739, 95% CI: 0.216-1.262, <i>p</i>=.006), left hand grip strength (ES=0.692, 95% CI: 0.167-1.217, <i>p</i>=.010), knee extension strength (ES=1.448, 95% CI: 0.273-2.624, <i>p</i>=.016), and timed up and go (ES=1.471, 95% CI: 0.492-2.450, <i>p</i>=.003) significantly improved in response to resistance exercise programs.CONCLUSIONS: Sarcopenia is increasing with the growing elderly population; thus prevention and effective interventions are very important. The data suggest that resistance exercise may be actual in enhancing not only appendicular muscle mass, but also knee extension strength and timed up and go in elderly diagnosed with sarcopenia. Further follow-up studies on larger populations and a variety of approaches are required to reconfirm these results.

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