scholarly journals The Three-item ALERT-B Questionnaire Provides a Validated Screening Tool to Detect Chronic Gastrointestinal Symptoms after Pelvic Radiotherapy in Cancer Survivors

2016 ◽  
Vol 28 (10) ◽  
pp. e139-e147 ◽  
Author(s):  
S. Taylor ◽  
A. Byrne ◽  
R. Adams ◽  
J. Turner ◽  
L. Hanna ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Screening Tool ◽  
Gastrointestinal Symptoms ◽  
Pelvic Radiotherapy

scholarly journals Cancer-related psychosocial factors and self-reported changes in lifestyle among gynecological cancer survivors: cross-sectional analysis of PROFILES registry data

2021 ◽  
Author(s):  
Karin A. J. Driessen ◽  
Belle H. de Rooij ◽  
M. Caroline Vos ◽  
Dorry Boll ◽  
Johanna M. A. Pijnenborg ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cancer Survivors ◽  
Psychosocial Factors ◽  
Initial Treatment ◽  
Gynecological Cancer ◽  
Gastrointestinal Symptoms ◽  
Cross Sectional ◽  
Body Change ◽  
Change Concerns ◽  
Gynecological Cancer Survivors

Abstract Purpose Obesity is prevalent in gynecological cancer survivors and is associated with impaired health outcomes. Concerns due to cancer and its treatment may impact changes in lifestyle after cancer. This study aimed to assess the association between cancer-related psychosocial factors and changes in physical activity and diet, 18 months after initial treatment among gynecological cancer survivors. Methods Cross-sectional data from the ROGY Care study were used, including endometrial and ovarian cancer patients treated with curative intent. The Impact of Cancer Scale (IOCv2) was used to assess cancer-related psychosocial factors. Self-reported changes in nutrients/food groups and in physical activity post-diagnosis were classified into change groups (less/equal/more). Multivariable logistic regression models were used to assess associations. Results Data from 229 cancer survivors (59% endometrial, 41% ovarian, mean age 66 ± 9.5, 70% tumor stage I) were analyzed. In total, 20% reported to eat healthier from diagnosis up to 18 months after initial treatment, 17% reported less physical activity and 20% more physical activity. Health awareness (OR 2.79, 95% CI: 1.38; 5.65), body change concerns (OR 3.04 95% CI: 1.71; 5.39), life interferences (OR 4.88 95% 2.29; 10.38) and worry (OR 2.62, 95% CI: 1.42; 4.85) were significantly associated with less physical activity up to 18 months after initial treatment whereby gastrointestinal symptoms were an important confounder. Conclusion(s) This study underlines the need to raise awareness of the benefits of a healthy lifestyle and to provide tailored lifestyle advice, taking into account survivors’ health awareness, body change concerns, life interferences, worry and gastrointestinal symptoms, in order to improve health behavior among gynecological cancer survivors. Trial Registration http://clinicaltrials.gov Identifier: NCT01185626, August 20, 2010

Patients' Perspectives of the Impact of Gastrointestinal Symptoms after Pelvic Radiotherapy

2006 ◽  
Vol 18 (5) ◽  
pp. 423 ◽  
Author(s):  
C. Goode ◽  
C. Gillespie ◽  
C. Hackett ◽  
J. Andreyev
Keyword(s):  
Gastrointestinal Symptoms ◽  
Pelvic Radiotherapy ◽  
The Impact

scholarly journals Neuropathic Pain in Breast Cancer Survivors: Using the ID Pain as a Screening Tool

2010 ◽  
Vol 39 (5) ◽  
pp. 882-889 ◽  
Author(s):  
Cielito Reyes-Gibby ◽  
Phuong Khanh Morrow ◽  
Michael I. Bennett ◽  
Mark P. Jensen ◽  
Sanjay Shete
Keyword(s):  
Breast Cancer ◽  
Neuropathic Pain ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Screening Tool

Discriminatory power of a 25-item distress screening tool CancerSupport Source: A cross-sectional study of 251 cancer survivors.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 9599-9599
Author(s):  
Melissa F Miller ◽  
C. Daniel Mullins ◽  
Ebere Onukwugha ◽  
Christopher Gayer ◽  
Mitch Golant ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Screening Tool ◽  
Psychosocial Care ◽  
Summary Score ◽  
Discriminatory Power ◽  
Support Network ◽  
Distress Screening ◽  
Cross Sectional ◽  
Study Objective ◽  
Cancer Support

9599 Background: Distress screening and integrated psychosocial care is imperative for cancer patients, yet no tools are specifically tailored for the community provider setting where the majority of US patients are treated. Any screening tool must be validated and effective at discriminating those at risk for greater distress and the associated poorer health outcomes. The study objective was to test the discriminatory power of a 25-item distress screening tool CancerSupportSource for use among cancer survivors. Methods: A total of 251 members (90% female, median age 57 years; mixed diagnoses, 46% breast, 9% gynecologic, 7% blood, 6% colorectal, 32% other) of a community-based cancer support network completed a web-based distress screening tool. Participants were asked to rate each of 25 items according to the question “Today, how concerned are you about…?” using a five-point scale (0 not at all to 4 very seriously concerned). A summary score was calculated as the count of items rated ≥2 and the item discrimination index (IDI) as the difference between proportions of high and low scorers rating an item≥2. Cut-points at 13 and 4 yielded equal-sized groups and were used to classify participants as high (n=59) and low scorers (n=60). Results: Items with the greatest discriminatory power (IDI≥0.8) were: changes or disruptions in work, school or home life; worrying about the future and what lies ahead; feeling too tired to do the things you need or want to do; feeling sad or depressed; ability to exercise or be physically active; and feeling nervous or afraid. Conversely, items with the lowest IDI included: eating and nutrition; tobacco or substance use; transportation to treatment and appointments; considering taking your own life. Conclusions: The results highlight, among 25 items of a distress screening tool, those items with the greatest discriminatory power to identify cancer survivors with psychosocial distress. Results suggest priority areas for distress screening and referral for support services.

Evaluating sexual function in adolescent and young adult childhood cancer survivors.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e24180-e24180
Author(s):  
Jenna Sopfe ◽  
Rebekah Marsh ◽  
Leslie C. Appiah ◽  
James L. Klosky ◽  
Pamela N Peterson ◽  
...  
Keyword(s):  
Young Adult ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Screening Tool ◽  
Childhood Cancer Survivors ◽  
Adolescent And Young Adult ◽  
Structured Interviews ◽  
Written Information ◽  
Promising Tool ◽  
Prior Experiences

e24180 Background: Up to half of adolescent and young adult (AYA) childhood cancer survivors (CCS) experience sexual dysfunction (SD) as a result cancer or its treatment. SD in CCS is under-recognized, with low levels of routine screening due to barriers such as discomfort, time, and awareness. This study explores solutions to these barriers by describing AYA CCS preferences for implementation of screening for SD and evaluating the utility of a validated adult screening tool (PROMIS SexFS Brief) in this population. Methods: 16 AYA CCS (aged 15-24 years) completed semi-structured interviews followed by questionnaire completion. Interviews explored patients’ prior experiences with SD screening, along with preferences for screening type (e.g., discussion, screening tool), delivery modality, and timing. Patients then completed the PROMIS SexFS Brief while verbalizing their thoughts and providing open-ended responses to each item. Transcribed interviews were inductively coded and analyzed, guided by content analysis methodology. Results: This analysis represents 2/3 of planned interviews, and all will be completed by April 1, 2020. Interviews were performed with 11 females and 5 males (median age 21). Preliminary analysis demonstrates that participants had minimal experience with SD conversations, but had preferences regarding by whom, how, and when screening/education should occur. Who: Participants felt providers should have preexisting rapport with their patients; preferences existed for provider role and sex/age. How: A combination of written materials and in-person conversations was preferred. Several acknowledged a desire to have a “warning” that the conversation would happen, such as through a questionnaire. Participants did not have a preference regarding delivery modality (paper vs. online). The PROMIS SexFS Brief appeared to demonstrate content validity and acceptability in AYA CCS. When: Participants wanted education and screening to occur regularly throughout cancer therapy and survivorship. SD conversations should be tailored developmentally to the patient. Conclusions: Our results demonstrate a theme throughout interviews of the importance of patient/provider rapport. Further, while AYA CCS prefer in-person conversations about SD, conversations should be preceded by written information or a questionnaire to increase patient preparedness/comfort. Preliminary findings suggest that the PROMIS SexFS Brief is a promising tool for screening SD in this population; further studies evaluating use in clinical settings is warranted.

Gastrointestinal symptoms after pelvic radiotherapy: a national survey of gastroenterologists

2011 ◽  
Vol 20 (9) ◽  
pp. 2129-2139 ◽  
Author(s):  
C. C. Henson ◽  
S. E. Davidson ◽  
A. Lalji ◽  
R. P. Symonds ◽  
R. Swindell ◽  
...  
Keyword(s):  
National Survey ◽  
Gastrointestinal Symptoms ◽  
Pelvic Radiotherapy

scholarly journals Long-term mucosal injury and repair in a murine model of pelvic radiotherapy

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Dilip K. Malipatlolla ◽  
Piyush Patel ◽  
Fei Sjöberg ◽  
Sravani Devarakonda ◽  
Marie Kalm ◽  
...  
Keyword(s):  
Cancer Survivors ◽  
Mucosal Injury ◽  
Mucosal Inflammation ◽  
Pelvic Radiotherapy ◽  
Linear Accelerators ◽  
Crypt Fission ◽  
Pelvic Cancer ◽  
Injury And Repair ◽  
Bowel Health

Abstract Chronic intestinal injury after pelvic radiotherapy affects countless cancer survivors worldwide. A comprehensive understanding of the long-term injury dynamics is prevented in available animal models. With linear accelerators that are used to treat cancer in patients, we irradiated a small volume encompassing the colorectum in mice with four fractions of 8 Gy per fraction. We then determined the long-term dynamics of mucosal injury, repair, and the duration of inflammation. We show that crypt fission, not cell proliferation, is the main long-term mechanism for rescuing crypt density after irradiation, and provides a potentially wide window for clinical interventions. Persisting macrophage aggregations indicate a chronic mucosal inflammation. A better understanding as to how crypt fission is triggered and why it fails to repair fully the mucosa may help restore bowel health after pelvic radiotherapy. Moreover, anti-inflammatory interventions, even if implemented long after completed radiotherapy, could promote bowel health in pelvic cancer survivors.

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