scholarly journals Systematic review of antibiotic consumption in acute care hospitals

2016 ◽  
Vol 22 (6) ◽  
pp. 561.e7-561.e19 ◽  
Author(s):  
R. Bitterman ◽  
K. Hussein ◽  
L. Leibovici ◽  
Y. Carmeli ◽  
M. Paul
2002 ◽  
Vol 7 (4) ◽  
pp. 128-135 ◽  
Author(s):  
Elizabeth J. Halcomb ◽  
Ritin S. Fernandez ◽  
Rhonda D. Griffiths

2017 ◽  
Vol 38 (4) ◽  
pp. 476-482 ◽  
Author(s):  
Irene K. Louh ◽  
William G. Greendyke ◽  
Emilia A. Hermann ◽  
Karina W. Davidson ◽  
Louise Falzon ◽  
...  

OBJECTIVEPrevention ofClostridium difficileinfection (CDI) in acute-care hospitals is a priority for hospitals and clinicians. We performed a qualitative systematic review to update the evidence on interventions to prevent CDI published since 2009.DESIGNWe searched Ovid, MEDLINE, EMBASE, The Cochrane Library, CINAHL, the ISI Web of Knowledge, and grey literature databases from January 1, 2009 to August 1, 2015.SETTINGWe included studies performed in acute-care hospitals.PATIENTS OR PARTICIPANTSWe included studies conducted on hospitalized patients that investigated the impact of specific interventions on CDI rates.INTERVENTIONSWe used the QI-Minimum Quality Criteria Set (QI-MQCS) to assess the quality of included studies. Interventions were grouped thematically: environmental disinfection, antimicrobial stewardship, hand hygiene, chlorhexidine bathing, probiotics, bundled approaches, and others. A meta-analysis was performed when possible.RESULTSOf 3,236 articles screened, 261 met the criteria for full-text review and 46 studies were ultimately included. The average quality rating was 82% according to the QI-MQCS. The most effective interventions, resulting in a 45% to 85% reduction in CDI, included daily to twice daily disinfection of high-touch surfaces (including bed rails) and terminal cleaning of patient rooms with chlorine-based products. Bundled interventions and antimicrobial stewardship showed promise for reducing CDI rates. Chlorhexidine bathing and intensified hand-hygiene practices were not effective for reducing CDI rates.CONCLUSIONSDaily and terminal cleaning of patient rooms using chlorine-based products were most effective in reducing CDI rates in hospitals. Further studies are needed to identify the components of bundled interventions that reduce CDI rates.Infect Control Hosp Epidemiol2017;38:476–482


Critical Care ◽  
2015 ◽  
Vol 19 (1) ◽  
Author(s):  
Gooske Douw ◽  
Lisette Schoonhoven ◽  
Tineke Holwerda ◽  
Getty Huisman-de Waal ◽  
Arthur R H van Zanten ◽  
...  

2020 ◽  
Author(s):  
Melanie Karrer ◽  
Angela Schnelli ◽  
Adelheid Zeller ◽  
Hanna Mayer

Abstract Background People with dementia are confronted with negative consequences due to hospital stays. When developing new interventions to improve the care of people with dementia in acute care hospitals, it is crucial to have a comprehensive overview of the previous interventions tested in this field and to know the investigated outcomes and effects. Methods We conducted a systematic review of interventional studies to provide an overview of interventions targeting the care situation of patients with dementia in acute care hospitals. We included trials with interventional study designs and systematic reviews of interventional studies with no restrictions regarding the outcomes. We searched five electronic databases, conducted a hand search of journals and performed forward and backward citation tracking of the included studies. For risk of bias assessment, we used the Cochrane Collaboration’s tool for assessing risk of bias in randomised trials, ROBANS (for non-randomised controlled trials) and AMSTAR (for systematic reviews). We provide tabular and narrative summaries of the findings. Results Nineteen studies met the inclusion criteria. he findings indicated a broad range of interventions and outcomes. We categorised the interventions into nine intervention types: educational programmes, family-/person-centred programmes, use of specially trained nurses, volunteer programmes, delirium management programmes, special care units and inpatient rehabilitation interventions. Staff outcomes were primarily investigated, followed by patient outcomes. Outcomes for relatives were only reported in three of the included studies. Educational programmes were the most commonly reported intervention type and showed improvements in staff outcomes. Family-/person-centred care programmes, use of specially trained nurses and delirium management programmes were able to improve patient-related outcomes, e.g. delirium severity, functional performance and rehospitalisation rates. Rehabilitation interventions after hip fractures and special care units for people with dementia showed hardly significant effects. Conclusions Although the included interventional studies were able to show improved outcomes for staff, relatives and patients, the evidence is insufficient to declare which interventions are effective in improving care for people with dementia in acute care hospitals. Future research should focus on patient and family caregiver outcomes. Furthermore, interventions addressing relatives, interprofessional collaboration and the entire practice culture are needed.


2020 ◽  
Author(s):  
Melanie Karrer ◽  
Angela Schnelli ◽  
Adelheid Zeller ◽  
Hanna Mayer

Abstract Background: People with dementia are confronted with negative consequences due to hospital stays. When developing new interventions to improve care for people with dementia in acute care hospitals (by intervention we understand organisational strategies, programmes, and/or treatments and actions performed by healthcare professionals), it is crucial to have a comprehensive overview of previous interventions tested in this field and to know the outcomes.Methods: We conducted a systematic review to provide an overview of interventions targeting the care situation of patients with dementia in acute care hospitals. We included trials with interventional study designs and systematic reviews without restrictions regarding the outcomes. We searched five electronic databases, conducted a hand search of journals and performed forward and backward citation tracking of included studies. For risk of bias assessment, we used the Cochrane Collaboration’s tool for assessing risk of bias in randomised trials, ROBANS (for non-randomised controlled trials) and AMSTAR (for systematic reviews). We provide tabular and narrative summaries of the findings. Results: Twenty studies met the inclusion criteria. The findings indicated a broad range of interventions and outcomes. We categorised the interventions into eight intervention types: educational programmes, special non-pharmacological interventions, delirium management programmes, inpatient rehabilitation interventions, family-/person-centred programmes, use of specially trained nurses, volunteer programmes and special care units. Staff outcomes were investigated in most of the studies, followed by patient outcomes. Outcomes concerning relatives were reported in four studies. Educational programmes were the most commonly reported intervention type and resulted in improved staff outcomes. Family-/person-centred care programmes, use of specially trained nurses and delirium management programmes were effective in improving patient-related outcomes, e.g. delirium severity and functional performance. Rehabilitation interventions after hip fractures and special care units for people with dementia hardly showed any significant effects. Conclusions: Although the included interventional studies reported improved outcomes concerning patients, relatives and staff, the evidence is insufficient to declare which interventions are effective in improving care for people with dementia in acute care hospitals. Future research should focus on relevant patient and family caregiver outcomes. Thereby, it is necessary to consider the complexity of the interventions. Interventions addressing relatives, interprofessional collaboration and the entire practice culture are needed. Trial registration: PROSPERO: CRD42018111032.


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