An organic solvent-free technology for the fabrication of albumin-based paclitaxel nanoparticles for effective cancer therapy

2019 ◽  
Vol 183 ◽  
pp. 110394 ◽  
Author(s):  
Yanna Zhao ◽  
Chang Cai ◽  
Min Liu ◽  
Yuping Zhao ◽  
Wenxin Pei ◽  
...  
2007 ◽  
Vol 2 (2) ◽  
pp. 303-306
Author(s):  
Haruyuki Okamura ◽  
Yoshimi Tajima ◽  
Tadahiro Ohba ◽  
Kanji Suyama ◽  
Masamitsu Shirai
Keyword(s):  

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zheng Wang ◽  
Jiangyong Miao ◽  
Lina Wang ◽  
Ying Liu ◽  
Hui Ji ◽  
...  

Abstract Background Presentation with massive systemic embolization as the initial manifestation of occult malignancy is infrequent. The standard management of cancer-related arterial thromboembolism has not yet been established. Case presentation We described a case of Trousseau’s syndrome resulting in acute ischemic stroke concomitant with multiple embolizations in the spleen and kidney during oral administration of dabigatran for pulmonary embolism preceding the diagnosis of a malignant tumor. A cancer-related hypercoagulable state was suspected because the patient was admitted to the neurology department due to acute ischemic stroke with three territory infarcts on diffusion-weighted imaging (DWI) in the absence of identifiable conventional risk factors and brain vessel narrowing. The patient was subsequently diagnosed with epidermal growth factor receptor (EGFR) mutation–positive non-small-cell lung cancer (NSCLC) (stage IV) with pleural metastasis. Administration of low-molecular-weight heparin followed by long-term dabigatran under effective cancer therapy comprising gefitinib and subsequent chemotherapy did not cause stroke relapse during the 1-year follow-up. Conclusions This case suggests that cancer-related hypercoagulability should be considered an important etiology for stroke patients who develop unexplained disseminated acute cerebral infarction without conventional stroke risk factors, especially concomitant with multiple organ embolization. Novel oral anticoagulants may be an alternative therapy for the long-term management of cancer-related arterial thromboembolism under effective cancer therapy.


Holzforschung ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Jingtian Chen ◽  
Miao Wang ◽  
Yong Qian ◽  
Shanyuan Tan ◽  
Huan Wang ◽  
...  

Abstract Lignin is a natural macromolecular sun blocker and provides an ideal protection material for pesticides that have poor photostability. In this study, alkali lignin/prochloraz capsules (AL-P) were prepared via one-pot ultrasonic cavitation. The results demonstrated that the produced AL-P were uniform spheres with sizes of 170–375 nm. The prochloraz encapsulation efficiency (EE) and loading capacity (LC) reached as high as 91.8 and 98.5%, respectively. Adding a small of surfactant reduced the size of the capsules, but both EE and LC were decreased. AL-P exhibited excellent extended release performance. The cumulative release of AL-P in the first 45 h was 76.1% and continuous release was maintained after 96 h. The resulting AL-P have improved photostability under UV irradiation radiation. Finally, AL-P capsules were sprayed on the mango leaves and bananas to act as preservatives, AL-P capsules had stronger rain wash resistance and were better preserved demonstrating their industrial applicability. Together, organic solvent free AL-P capsules demonstrate a method to improve the efficiency of photosensitive pesticides.


2021 ◽  
Vol 13 (10) ◽  
pp. 12347-12358
Author(s):  
Sihan Zhang ◽  
Guanglei Zhao ◽  
Jiming Wang ◽  
Chong Xie ◽  
Wenquan Liang ◽  
...  

2021 ◽  
Author(s):  
Hang Mei ◽  
Huajing Liu ◽  
Qianqian Shang ◽  
Ying Dong ◽  
Stig Pedersen-Bjergaard ◽  
...  

A versatile organic-solvent-free electromembrane extraction (EME) system, which could be successfully used for the extraction of both basic and acidic analytes, is proposed based on semi-interpenetrating polymer networks.


2015 ◽  
Vol 128 (3) ◽  
pp. 1062-1067 ◽  
Author(s):  
Tianjiao Ji ◽  
Ying Zhao ◽  
Yanping Ding ◽  
Jing Wang ◽  
Ruifang Zhao ◽  
...  

2006 ◽  
Vol 23 (9) ◽  
pp. 2190-2199 ◽  
Author(s):  
Arnaud Béduneau ◽  
Patrick Saulnier ◽  
Nicolas Anton ◽  
François Hindré ◽  
Catherine Passirani ◽  
...  

RSC Advances ◽  
2021 ◽  
Vol 11 (21) ◽  
pp. 12990-12994
Author(s):  
Abolfazl Olyaei ◽  
Amir Mohamadi ◽  
Nilufar Rahmani

The synthesis of a new class of lawsone enaminone derivatives by using lawsone, triethyl orthoformate and aromatic amines in the presence of guanidinium chloride under solvent-free conditions has been developed.


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