Metabotropic glutamate receptor involvement in the pathophysiology of amyotrophic lateral sclerosis: new potential drug targets for therapeutic applications

Glutamate Receptor ◽

Drug Targets ◽

Potential Drug ◽

Therapeutic Applications ◽

Metabotropic Glutamate ◽

Potential Drug Targets ◽

Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Neurobiology of Disease ◽

10.1016/j.nbd.2013.11.006 ◽

2014 ◽

Vol 64 ◽

pp. 48-59 ◽

Cited By ~ 25

Author(s):

Marco Milanese ◽

Francesco Giribaldi ◽

Marcello Melone ◽

Tiziana Bonifacino ◽

Ilaria Musante ◽

...

Keyword(s):

Mouse Model ◽

Disease Progression ◽

Glutamate Receptor ◽

Metabotropic Glutamate ◽

Metabotropic Glutamate Receptor 1 ◽

Sod1g93a Mouse ◽

Loss of metabotropic glutamate receptor-mediated regulation of glutamate transport in chemically activated astrocytes in a rat model of amyotrophic lateral sclerosis

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2005.03577.x ◽

2006 ◽

Vol 96 (3) ◽

pp. 719-731 ◽

Cited By ~ 44

Author(s):

Celine Vermeiren ◽

Isabelle Hemptinne ◽

Nicolas Vanhoutte ◽

Sebastien Tilleux ◽

Jean-Marie Maloteaux ◽

...

Keyword(s):

Glutamate Receptor ◽

Rat Model ◽

Glutamate Transport ◽

Metabotropic Glutamate ◽

Protective effect of metabotropic glutamate receptor inhibition on amyotrophic lateral sclerosis–cerebrospinal fluid toxicity in vitro

Neuroscience ◽

10.1016/j.neuroscience.2006.05.044 ◽

2006 ◽

Vol 141 (4) ◽

pp. 1879-1886 ◽

Cited By ~ 18

Author(s):

J.M.H. Anneser ◽

C. Chahli ◽

G.D. Borasio

Keyword(s):

Cerebrospinal Fluid ◽

Protective Effect ◽

Glutamate Receptor ◽

Metabotropic Glutamate ◽

Receptor Inhibition ◽

Toxicity In Vitro ◽

Adenosine and Its Receptors as Potential Drug Targets in Amyotrophic Lateral Sclerosis

Journal of Caffeine and Adenosine Research ◽

10.1089/caff.2019.0016 ◽

2019 ◽

Vol 9 (4) ◽

pp. 157-166

Author(s):

Yijuang Chern ◽

Nádia Rei ◽

Joaquim A. Ribeiro ◽

Ana M. Sebastião

Keyword(s):

Drug Targets ◽

Potential Drug ◽

Potential Drug Targets ◽

In-vivo genetic ablation of metabotropic glutamate receptor type 5 slows down disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis

Neurobiology of Disease ◽

10.1016/j.nbd.2019.05.007 ◽

2019 ◽

Vol 129 ◽

pp. 79-92 ◽

Cited By ~ 3

Author(s):

Tiziana Bonifacino ◽

Francesca Provenzano ◽

Elena Gallia ◽

Silvia Ravera ◽

Carola Torazza ◽

...

Keyword(s):

Mouse Model ◽

Disease Progression ◽

Glutamate Receptor ◽

Genetic Ablation ◽

Metabotropic Glutamate ◽

Sod1g93a Mouse ◽

In-vivo effects of knocking-down metabotropic glutamate receptor 5 in the SOD1 G93A mouse model of amyotrophic lateral sclerosis

Neuropharmacology ◽

10.1016/j.neuropharm.2017.06.020 ◽

2017 ◽

Vol 123 ◽

pp. 433-445 ◽

Cited By ~ 11

Author(s):

Tiziana Bonifacino ◽

Luca Cattaneo ◽

Elena Gallia ◽

Aldamaria Puliti ◽

Marcello Melone ◽

...

Keyword(s):

Mouse Model ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate ◽

In Vivo Effects ◽

Lateral Sclerosis ◽

Sod1 G93a Mouse

Glial Proliferation and Metabotropic Glutamate Receptor Expression in Amyotrophic Lateral Sclerosis

Journal of Neuropathology & Experimental Neurology ◽

10.1093/jnen/63.8.831 ◽

2004 ◽

Vol 63 (8) ◽

pp. 831-840 ◽

Cited By ~ 45

Author(s):

Johanna M. H. Anneser ◽

Christine Chahli ◽

Paul G. Ince ◽

Gian Domenico Borasio ◽

Pamela J. Shaw

Keyword(s):

Glutamate Receptor ◽

Receptor Expression ◽

Metabotropic Glutamate ◽

Glial Proliferation ◽

Metabotropic glutamate receptors: potential drug targets

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)44554-x ◽

1997 ◽

Vol 73 ◽

pp. 11

Author(s):

Masamichi Okada ◽

Shioeki Kawabata ◽

Tokio Yamaquchi

Keyword(s):

Glutamate Receptors ◽

Drug Targets ◽

Metabotropic Glutamate Receptors ◽

Potential Drug ◽

Metabotropic Glutamate ◽

Potential Drug Targets

Metabotropic Glutamate Receptors: Potential Drug Targets for the Treatment of Schizophrenia

Current Drug Targets - CNS & Neurological Disorders ◽

10.2174/1568007023339337 ◽

2002 ◽

Vol 1 (3) ◽

pp. 261-281 ◽

Cited By ~ 62

Author(s):

Laura Chavez-Noriega ◽

Herve Schaffhauser ◽

Una Campbell

Keyword(s):

Glutamate Receptors ◽

Drug Targets ◽

Metabotropic Glutamate Receptors ◽

Potential Drug ◽

Metabotropic Glutamate ◽

Potential Drug Targets

Group II metabotropic glutamate receptor agonists as a potential drug for schizophrenia

European Journal of Pharmacology ◽

10.1016/j.ejphar.2009.12.041 ◽

2010 ◽

Vol 639 (1-3) ◽

pp. 59-66 ◽

Cited By ~ 41

Author(s):

Shigeyuki Chaki

Keyword(s):

Glutamate Receptor ◽

Potential Drug ◽

Receptor Agonists ◽

Metabotropic Glutamate ◽

Glutamate Receptor Agonists ◽

Group Ii