scholarly journals Comparison of two amoxicillin/clavulanic acid-resistant profiles employing two types of assay disks: A pilot study in 50 isolates from a tertiary care hospital in India

2006 ◽  
Vol 67 (2) ◽  
pp. 151-156 ◽  
Author(s):  
Subhash C. Arya ◽  
Nirmala Agarwal ◽  
Shekhar Agarwal
2014 ◽  
Vol 3 (23) ◽  
pp. 6378-6381
Author(s):  
Nikhil Kumar Tudu ◽  
Rupali Dey ◽  
Indrani Bhattacharya ◽  
Soumitra Roy ◽  
Jayanta Bikash Dey

2021 ◽  
Vol 35 (2) ◽  
pp. 58
Author(s):  
AnupmaJyoti Kindo ◽  
Shibani Mishra ◽  
Anitha Subramanian

Antibiotics ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 778
Author(s):  
Alexandre Castro-Lopes ◽  
Sofia Correia ◽  
Cátia Leal ◽  
Inês Resende ◽  
Pedro Soares ◽  
...  

Background: The COVID-19 pandemic poses novel challenges in antimicrobial consumption metrics and stewardship strategies. COVID-19 patients became the major cause of hospital admission during the first wave of the pandemic, often leading to an antimicrobial prescription upon admission or treatment for superinfections. The aim of this study was to understand how antimicrobial consumption was impacted at the beginning of the pandemic in a tertiary care hospital, a reference center for COVID-19. Materials and Methods: A retrospective before-and-after study was done. Descriptive statistics of discharges, patient-days, and antimicrobial use indicators (defined daily doses (DDD)/100 discharges, DDD/100 patient-days) for various groups were calculated for the first three months of the pandemic (March, April, and May 2020) as a quarterly value, and for each year in 2011–2019, and their annual percentage changes were used to estimate 95% confidence intervals. The indicators were compared to patient type (medical/surgical), type of admission (urgent/elective), and age groups using Spearman’s correlation coefficient. Results: Statistically significant increases occurred in 2020 for total antibacterials, macrolides, cephalosporins, amoxicillin/clavulanic acid, carbapenems, meropenem, and third-generation cephalosporins, while a reduction was seen in cefazolin/cefoxitin. A correlation was found between antibacterial consumption and patient or admission type. In 2020, unlike in pre-pandemic years, there was a different impact in DDD/100 discharges and DDD/100 patient-days due to increased lengths-of-stay and longer antimicrobial therapy. Conclusions: The COVID-19 pandemic led to an increase in antimicrobial consumption with a different impact in DDD/100 discharges and DDD/100 patient-days. This highlights the need to use both indicators simultaneously to better understand the causes of antimicrobial consumption variation and improve the design of effective antimicrobial stewardship interventions.


2021 ◽  
Vol 9 (2) ◽  
pp. 43-47
Author(s):  
Alwadei Mohamed ◽  
Taher Nada ◽  
Saleh Yasir ◽  
Alharthi Bassam ◽  
Kutbi Omniyyah ◽  
...  

2017 ◽  
Vol 1 (1) ◽  
pp. 28
Author(s):  
Laraib Malik

Introduction: P.I.C.U is a unit that provides care to the critically ill patients with purpose of reducing the rate of mortality and morbidity. Various scoring systems are used to assess and compare the standards of care of different P.I.C.U.s. Among them, PRISM III scoring has shown promising results, especially in developing countries. In Pakistan, these studies are fewer in numbers with conflicting results in different hospital settings (private and public sector). Since our hospital is also a tertiary care hospital, we planned a pilot study to evaluate PRISM III score in our P.I.C.U.    Objective: To evaluate the performance of PRISM III score in predicting the    outcome of patients admitted in P.I.C.U of tertiary care hospital of Karachi. Method: PRISM III is Pediatric Risk of Mortality Scoring system consisting of clinical    assessment (Glasgow Coma Scale, pupillary reflex, temperature, heart rate, systolic blood pressure) and lab parameters (arterial blood gas, urea, nitrogen, creatnine, blood sugar, potassium, white cell count, platelets, PT/APTT). It is a cross-sectional study and data was collected from admitted patients in P.I.C.U, Unit II of Abbasi Shaheed Hospital during 1st October to 31st December 2016. PRISM score is being calculated from all the patients within 24 hours of admission. Result: Total of 70  patients of which 51(72%) survived and 19(27%) expired. 49 were males and 21   females. Age range of non-survivors was 2 to 18 months. Duration of PI.C.U stay was 72 hours for survivors. Patients who were referred, had malnutrition, depressed  mental status, deranged renal functions and required mechanical ventilation during first hour of admission had poor outcome. Out of 19 non-survivors, PRISM III   predicted mortality in 15 patients (78.9%). Conclusion: High total PRISM III score was significantly associated with poor outcome i.e. death in this pilot study. Thus PRISM III score was found to be a valid predictor of outcome in our P.I.C.U. There is no conflict of interest keywords: P.I.C.U, Mortality, PRISM III score, Outcome.


2017 ◽  
Vol 61 (5) ◽  
pp. 63
Author(s):  
AG Radhika ◽  
Sruthi Bhaskaran ◽  
Jagdish Kaur ◽  
Anshuja Singla ◽  
Tusha Sharma ◽  
...  

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