tinea cruris
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2021 ◽  
Vol 7 (4) ◽  
pp. 315-319
Author(s):  
U Ketan Raju ◽  
Hanamant G Bobade ◽  
Anil Mishra

Dermatophytes are aerobic fungi that produce proteases that digest keratin and allows colonization, invasion and infection of the stratum corneum of the skin, the hair shaft, and the nail. This study was an attempt on the part of the author to find out the incidence and various clinico-epidemiological characteristics of Dermatophytosis in skin OPD of Tertiary care Hospital, B.K.L.W.R.M.C., Dervan. The study was carried on 2444 patients of Dermatophytosis attending the OPD, out of which 49.79% of the cases were Tinea Cruris (TC). The age group of 11-20 years showed maximum prevalence of Dermatophytosis (22.17%). 58% of the patients had diffuse lesions. Body involvement was seen in 87% of cases. Itching was the most common condition associated with Dermatophytosis. 35% of the patients reported with family history of Tinea Cruris.Circumscribed variety of TC was found to be most common variant mostly observed in 2and 4 decade, with a male preponderance. Groin was the most common site with multiple lesions. Nail changes was most commonly associated with TC.


2021 ◽  
Vol 7 (4) ◽  
pp. 331-336
Author(s):  
Sushmita Agrahari ◽  
Shivam ◽  
Shitij Goel ◽  
Gopi Krishna Maddali

Dermatophytosis are fungal infections caused by three genera of fungi that have the unique ability to invade and multiply within keratinized tissue (hair, skin, and nails). Although dermatomycoses are globally distributed, the endemic and most prevalent species of dermatophytosis differ strikingly from one geographic locality to another. Changing trend has been noticed in last few years with dermatophytic infections presenting as chronic, treatment unresponsive and recurrent. Also various microscopic and fungal culture studies have shown shift in identification of causative fungal species in recent years. Numerous studies have been done on the occurrence of dermatophytes in various parts of our country illustrating the range and changing pattern of fungal infection as well as causative fungal species. Total number of 150 patients attending outpatient department of our hospital who were clinically diagnosed as having superficial dermatophytosis were enrolled into the study. Patients were carefully screened as per inclusion and exclusion criteria and then enrolled in the study. Samples were taken from all the patients and examined for KOH direct microscopy and sent for fungal culture on Sabouraud’s Dextrose Agar as well as on Dermtophyte Test Medium. Results were then analyzed using standard statistical methods. Out of total 150 patients, 101 were males and 49 were females. Most common age group was 21-30 years (37.3%). 58 patients (38.7%) showed positivity to KOH microscopy as well as fungal culture. Additionally 25 more samples demonstrated positivity to KOH microscopy (total 83 patients) but negativity to culture, while 9 patient samples were positive to culture but negative to direct microscopy. Predominant fungal species isolated on culture was Trichophyton mentagrophytes (50.7%) while next common species isolated was T. tonsurans (29.9%). No significant association was found between dermatophyte isolate on culture and clinical type. Trichophyton mentagrophytes and Trichophyton tonsurans were the most common species isolated among subjects with Tinea faciei, Tinea cruris and Tinea corporis. The study showed a male preponderance and T. corporis was the commonest clinical type found. Majority of patients were in the 3rd decade and came within a duration of 1 month to 6 months of getting an infection. In patients diagnosed with tinea corporis, tinea cruris, tinea pedis and tinea manuum, T. mentagrophytes was the most predominant species isolated.


2021 ◽  
pp. 42-45
Author(s):  
Vasudha Sharma ◽  
Navyug Raj Singh ◽  
Tejinder Kaur ◽  
Inderpal Singh Grover

Background: The prevalence of recalcitrant tinea is increasing despite available treatment options. Itraconazole and terbinane are the most commonly prescribed agents for tinea. The relative efcacy of both the drugs is under focus and no standard guidelines exist for the recalcitrant tinea. Objective:To compare their relative efcacy and safety of itraconazole and terbinane in recalcitrant tinea cruris patients. Methods: A prospective, randomized, open label study recruited 100 recalcitrant tinea cruris patients of 18-65 years age at dermatology OPD at GNDH hospital, Amritsar, India after obtaining Institutional Ethics Committee approval. Patients who consented for study and follow up were included. Impaired hepatic/ renal function, secondary bacterial infections or deep mycoses patients were excluded. After randomization, group Acomprised of 50 patients who were put on capsule itraconazole 100 mg BD and group B of 50 patients on tablet terbinane 250 mg OD for eight weeks. The treatment response was assessed as Complete cure, Treatment failure based on clinical (PGAScore) and mycological (KOH Smear) prole. Results: Itraconazole resulted in complete cure in 28 patients whereas terbinane cured 14 patients completely (p <0.05). Treatment failure were observed as 1 and 8 (itraconazole and terbinane respectively, p < 0.05). Both drugs had comparable safety prole with no serious adverse effects. Limitations of the study were short duration, small sample size and non-blinding. Conclusion:Itraconazole seems relatively more efcacious than terbinane in the treatment recalcitrant tinea cruris cases


2021 ◽  
Vol 14 (3) ◽  
pp. 1543-1549
Author(s):  
S. Brigida ◽  
Arul Amutha Elizabeth ◽  
G. Soujania ◽  
R. Poornima Poornima

Introduction: Superficial dermatophytosis is a common public health problem in India, due to its tropical climate with heat and humidity. Today, the triazoles, mainly Itraconazole and the allylamines, chiefly Terbinafine, are the main ammunitions against dermatophytes. This study is undertaken to compare the safety and efficacy of both the drugs. Materials and Methods: This study was conducted to find the efficacy of Oral Terbinafine and Oral Itraconazole in Tinea Corporis/Tinea Cruris infection. The primary efficacy parameter was change in composite score (pruritus, erythema, pigmentations) from baseline to end of the treatment period. And to compare the safety of Oral Terbinafine and Oral Itraconazole by comparing the following parameters, Liver enzymes - SGOT/SGPT before and after treatment with the study drugs. Drug Dosage: Group 1: Drug –Tab. Terbinafine: Dose 500 mg per day once daily at bedtime for 2 weeks. Group 2: Drug –Tab. Itraconazole: Dose 200 mg per day, once daily at bedtime for 2 weeks. Results: The study participants show significant reduction in itching at the second follow up (after 2 weeks of drug completion) in both groups. Pruritis was reduced in 92% subjects in group 1 and 97.5% subjects in group 2. There was 87% reduction in erythema in group 1 and 93% reduction in group 2. Pigmentations were seen in 2% subjects in both groups indicating relapse of infection. Conclusion: The significant outcome of the study was that oral Itraconazole 200mg/day for 14 days(2 weeks) can be the better antifungal.


2021 ◽  
pp. 31-33
Author(s):  
Purushottam Kumar ◽  
Sudeb Roy ◽  
Debarshi Jana

INTRODUCTION Fungal infections are very common in human beings, especially cutaneous fungal infections in which supercial keratinized tissue of the stratum corneum of the skin, hair and nail are involved by a group of specialized fungi known as Dermatophytes and the condition is known as Dermatophytosis. These dermatophytes use keratin as a nitrogen source. Dermatophytes produce only supercial infections of the skin and its appendages without involving the deeper tissue or the internal organs.AIM OFPROPOSED RESEARCH General objectives This study is to determine the proportion and distribution pattern of the etiological agents of dermatophytosis among the clinically suspected cases, attending the dermatology OPD of Calcutta National Medical College and Hospital with specic dermatological complaints, taking into account, the different parameters like age, sex, occupation of the patient, associated relevant co-morbidity if any, socio- economic condition and nature of the dermatological condition. MATERIALAND METHODS Study design: Observational, Cross sectional, Hospital based study. Study setting and time lines: Submission of thesis synopsis - within 30th November 2017. Data collection: After approval by the ethical committee, data was collected for the next 1year. Data analysis and submission is done in following 6 months. Place of study: Department of Microbiology and department of Dermatology at Calcutta National Medical College and Hospital Kolkata (WB) Period of study: One year from March 2018 to March 2019 Study population: Clinically suspected cases with specic dermatological complaints attending the dermatology OPD of Calcutta National Medical College and Hospital.Sample Size/Design Sample Size: Altogether 200 samples (approximately) including nail, skin scrapings and hair samples.RESULTS AND ANALYSIS Our study showed that out of 200 clinically suspected cases, 112 were male and 88 were female, 153 were KOH positive and 47 were KOH negative, and 125 found to be suggestive for dermatophyte of different species, on cultivation. Remaining 75 were either contaminant, fungi of other than dermatophytes like aspergillus yeast cells malasagia furfur etc or did not show any positive reports on KOH mount preparation and growth on culture media. CONCLUSIONS The most common clinical type was tinea corporis followed by tinea cruris and tinea pedis and overall predominance in the study was female with 16-55 being most affected age group. T. verrucosum forms the commonest etiological agent of dermatophytosis, which were mostly isolated from Tinea corporis, Tinea cruris Tinea unguinum,and Tinea manuum. Possible cause of dermatophytic infection in lower socioeconomic groups were due to more exposed to the infections and because of their lack of awareness as well as poorer knowledge on hygiene on fungal infection and its preventive measures.


Author(s):  
Sourabh G. Deshmukh ◽  
Trupti Thakre ◽  
Jaya Gupta ◽  
Rohit Waskar

Tinea Cruris is the disease of fungal infection of groin by dermatophyte fungi. It is commonly seen in men, and also called as Jock Itch as the other name. It is the condition which shows characteristics of disease as erythema, itching, burning sensation, cracked skin, skin rashes which worsen by exercise, skin discoloration and important symptom like rashes does not clears but increases due to antifungal creams. The management of the condition can be done in Ayurvedic perspective. According to Ayurveda all the classified disease of skin are considered as in Kushta Roga (skin disease), where the conditions of fungal infections are correlated with the Dadru Kshudra Kushta (Tinea). Due the clinical features of itch, redness, circular patches. The disease having exaggerated state of Pitta and Kapha Dosha, moreover Kapha. The treatment principle in such conditions is Shodhan Purificaton therapy along with Shaman (Pacificatory) therapy, as both therapies are considered best in Kushta Roga according to Acharyas. This case report is of the female patient suffered from itching over left thigh region along with redness, pimples, and round patches since 3 months, the patient finds the relief after following the Ayurvedic treatment as Shodhan Karma and Shaman Karma with lifestyle changes. The symptoms were diminished by Vaman Karma (emesis). She got 80-90% relief after Shodhan Karma as if one can consider the best treatment for tinea cruris.


2021 ◽  
Vol 11 (6) ◽  
pp. 135-139
Author(s):  
Zeba Waheed ◽  
Ram Krishna Ghosh ◽  
Aniruddha Banerjee

Dermatophytes, the most common causative agents, are assuming high significance in developing countries like India. These organisms metabolise keratin and cause a range of pathologic clinical presentations, including tinea pedis, tinea corporis, tinea cruris, etc. Although usually painless and superficial, these fungi can behave in an invasive manner, causing deeper and disseminated infection and should not be neglected. The lesions may become widespread and may have significant negative social, psychological, and occupational health effects, and can compromise the quality of life significantly. The recent prevalence of dermatophytosis in India ranges from 36.6-78.4%. Currently, dermatologists across India are inundated with cases of dermatophytosis presenting with unusual large lesions, ring within ring lesions, multiple site lesions (tinea cruris et corporis), and corticosteroid modified lesions, making diagnosis a difficult bet. 1 First line of therapy has always been a topical agent; while in resistance of the topical agents next preferred treatment are the oral therapies of antifungal agents (Ketoconazole, Terbinafine, Fluconazole and Itraconazole). However complementary and alternative therapy has also shown the significant results in control of growth of these dermatophytes. Homoeopathy has always been a safe and cost effective treatment in cases of dermatophyte infections.2 The present case report of a 31 years old Muslim female, Sepia officinalis 1M and Sulphur (30C and 200C) have shown marked improvement in the reduction of the lesion. Key words: Tinea corporis, homoeopathy, totality of symptoms, repertorisation.


2021 ◽  
Vol 33 (1) ◽  
pp. 34
Author(s):  
Selvia Yuliani Dwi Ratih Sanggarwati ◽  
Manik Retno Wahyunitisari ◽  
Linda Astari ◽  
Evy Ervianti

Background: Tinea corporis and cruris are dermatophytes that infect the skin, and they are caused by Trichophyton sp., Microsporum sp., and Epidermophyton sp. Dermatophyte fungal-infect keratin-containing skin classified by the body’s location, such as tinea corporis (skin besides haired area, body, hands, or feet) and tinea cruris (groin & perineal region). Purpose: To evaluate the clinical profiles and treatments of tinea corporis and cruris at Dermatology and Venereology (DV) outpatient clinic Dr. Soetomo General Academic Hospital in 2018. Methods: A retrospective-descriptive study based on medical records of DV outpatient clinic Dr. Soetomo General Academic Hospital, Surabaya. Data collected from August to December 2019. Tinea corporis and cruris profiles evaluation based on age, sex, occupation, precipitating factors, complaints, illness duration, family history, lesion’s location and description, and therapy. Result: A total of 164 patients (35 tinea corporis, 76 tinea cruris, and 53 tinea corporis and cruris), predominantly female, age 46–55 years, came treatment less-than-a-month cases, excessive sweating, itching, tinea corporis lesion’s location on the face and body, tinea cruris in  groin, tinea corporis and cruris on body and groin, erythematous macules, firm borders, active margins, scales, central healing, positive KOH 10–20% examination, miconazole cream therapy 2%, griseofulvin therapy, griseofulvin oral and ketoconazole cream 2% combination therapy. Discussion: Tinea corporis and cruris are common in females as their history and symptoms supported by the characteristics of laboratory examination, the presence of hyphae in potassium hydroxide (KOH) 10–20%. Most patients were prescribed with oral griseofulvin, especially in large lesions cases.


Author(s):  
Yogeshwari Gupta ◽  
◽  
Sonia Tuteja ◽  
Ankita Acharya ◽  
Vikrant Tripathi ◽  
...  

Dermatophytoses refers to superficial fungal infection of keratinized tissues caused by keratinophilic dermatophytes. According to observations worldwide, dermatophytoses are the most common of the superficial fungal infections. It is common in tropics and may present in epidemic proportions in areas with high rates of humidity. This prospective, longitudinal, observational study was conducted at SKHMC, Jaipur for a period of 1 year (April 2018 to March 2019), aiming to ascertain the effectiveness of homoeopathic medicines in the treatment of Tinea corporis and Tinea cruris. In this study, 65 cases of Tinea Infection (33 cases of Tinea cruris & 32 cases of Tinea corporis) were treated with homoeopathic medicines prescribed on the basis of totality of the symptoms. Treatment outcomes were assessed using Clinical Symptom Score, designed for this study & approved by Institutional Ethical Committee. Out of 65 patients, 41 patients (63.1%) got improved; 19 patients (29.2%) were at status quo and 05 patients (07.7%) became worse. Maximum patients were found to be in the age group of 11-40 years (n=50; 76.9%). Males were observed to be affected more as compared to females. Paired t-test was conducted on the Clinical Symptom Scores obtained before and after treatment and the result showed that p value is < 0.05 & value of t (11.623) is greater than the tabulated value in t-table at df = 64 (1.997), which was statistically significant and which also concluded that homoeopathic medicines were effective in treating Tinea corporis and Tinea cruris. Keywords Homeopathy; Dermatophytoses; Fungal infection; Observational study


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