Endothelial monocyte activating polypeptide II in children and adolescents with type 1 diabetes mellitus: Relation to micro-vascular complications

Cytokine ◽  
2015 ◽  
Vol 76 (2) ◽  
pp. 156-162 ◽  
Author(s):  
Amira A.M. Adly ◽  
Eman A. Ismail ◽  
Lamis M. Tawfik ◽  
Fatma S.E. Ebeid ◽  
Asmaa A.S. Hassan
2002 ◽  
Vol 57 (1) ◽  
pp. 113-116 ◽  
Author(s):  
F. Chiarelli ◽  
A. Mohn ◽  
S. Tumini ◽  
D. Trotta ◽  
A. Verrotti

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Katarzyna Zorena ◽  
Dorota Raczyńska ◽  
Piotr Wiśniewski ◽  
Ewa Malinowska ◽  
Małgorzata Myśliwiec ◽  
...  

The aim of this study was to evaluate the relationship between serum transforming growth factorβ1 (TGF-β1) concentrations and the duration of type 1 diabetes mellitus (T1DM) in children and adolescents. One hundred and sixteen patients with T1DM and 19 healthy controls were examined. Serum TGF-β1 concentrations were measured using the cytometric bead array (CBA). A positive association between the time of diabetes duration and higher serum TGF-β1 concentrations was observed. Similarly, the prevalence of microvascular complications, such as retinopathy and nephropathy, increased with the duration of diabetes. Logistic regression analysis showed that serum TGF-β1 concentrations and the duration of the disease are independent risk factors of microangiopathy development. Higher serum TGF-β1 concentrations were associated with a significant risk of microangiopathy development after 10 years of T1DM duration. In the successive years of the disease, the effect was even stronger. The results of our study indicate that serum TGF-β1 concentrations are one of the factors that may have an impact on the progression of vascular complications in children and adolescents with T1DM.


Author(s):  
Sattik Siddhanta ◽  
◽  
Soumik Goswami ◽  
Nilanjan Sengupta ◽  
Pranab Kumar Sahana ◽  
...  

Mauriac syndrome (MS) is one of the rare complications of poorly controlled Type 1 Diabetes Mellitus (T1DM). It is characterized by poor glycemic control, short stature hepatomegaly, Cushingoid features and delayed puberty [1]. Since the introduction and easy availability of longer acting insulin and insulin analogues, cases of Mauriac syndrome are hardly reported now [2]. This syndrome is more frequently encountered in children and adolescents with poor glycemic control and increases susceptibility of micro vascular complications of Diabetes like diabetic retinopathy and diabetic nephropathy. It is the most common cause of hepatic dysfunction in children and adolescents with Type 1 diabetes mellitus [3]. A classical case of Mauriac syndrome (MS) in an adolescent girl of uncontrolled Type 1 Diabetes Mellitus is being presented.


2013 ◽  
Author(s):  
Parthasarathy Lavanya ◽  
Khadilkar Anuradha ◽  
Ekbote Veena ◽  
Chiplonkar Shashi ◽  
Mughal Zulf ◽  
...  

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 795-P
Author(s):  
DALIA DALLE ◽  
SARINE G. SHAHMIRIAN ◽  
MARYANN O'RIORDAN ◽  
TERESA N. ZIMMERMAN ◽  
JAMIE R. WOOD

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