scholarly journals The Retromer Coat Complex Coordinates Endosomal Sorting and Dynein-Mediated Transport, with Carrier Recognition by the trans-Golgi Network

2009 ◽  
Vol 17 (1) ◽  
pp. 110-122 ◽  
Author(s):  
Thomas Wassmer ◽  
Naomi Attar ◽  
Martin Harterink ◽  
Jan R.T. van Weering ◽  
Colin J. Traer ◽  
...  
2017 ◽  
Vol 216 (11) ◽  
pp. 3433-3436 ◽  
Author(s):  
John P. Chamberland ◽  
Brigitte Ritter

The highly conserved retromer complex has been linked to cargo retrieval from endosomes to the trans-Golgi network. In this issue, Kvainickas et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201702137) and Simonetti et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201703015) fundamentally question the current retromer model and demonstrate that in mammalian cells, the individual retromer subcomplexes have functionally diverged to organize multiple distinct sorting pathways.


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