Differential expression of retinoic acid alpha and beta receptors in neuronal progenitors generated from human embryonic stem cells in response to TTNPB (a retinoic acid mimetic)

2021 ◽  
Author(s):  
Madhurima Das ◽  
Prasad Pethe
Keyword(s):  
Stem Cells ◽  
Retinoic Acid ◽  
Embryonic Stem Cells ◽  
Differential Expression ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Neuronal Progenitors ◽  
Beta Receptors

Ultrastructure of Human Embryonic Stem Cells and Spontaneous and Retinoic Acid-Induced Differentiating Cells

2004 ◽  
Vol 28 (4) ◽  
pp. 229-238 ◽  
Author(s):  
Sung-Hye Park ◽  
Seong Hoe Park ◽  
Myeong-Cherl Kook ◽  
Eun-Young Kim ◽  
Sepill Park ◽  
...  
Keyword(s):  
Stem Cells ◽  
Retinoic Acid ◽  
Embryonic Stem Cells ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem

scholarly journals Development of a Neural Teratogenicity Test Based on Human Embryonic Stem Cells: Response to Retinoic Acid Exposure

2011 ◽  
Vol 124 (2) ◽  
pp. 370-377 ◽  
Author(s):  
Silvia Colleoni ◽  
Cesare Galli ◽  
John Antony Gaspar ◽  
Kesavan Meganathan ◽  
Smita Jagtap ◽  
...  
Keyword(s):  
Stem Cells ◽  
Retinoic Acid ◽  
Embryonic Stem Cells ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Acid Exposure

scholarly journals All-trans retinoic acid and basic fibroblast growth factor synergistically direct pluripotent human embryonic stem cells to extraembryonic lineages

2013 ◽  
Vol 10 (2) ◽  
pp. 228-240 ◽  
Author(s):  
Smita Jagtap ◽  
Kesavan Meganathan ◽  
Vilas Wagh ◽  
Karthick Natarajan ◽  
Jürgen Hescheler ◽  
...  
Keyword(s):  
Stem Cells ◽  
Retinoic Acid ◽  
Embryonic Stem Cells ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Fibroblast Growth ◽  
Trans Retinoic Acid ◽  
All Trans Retinoic Acid

Anterior-Posterior Patterning of Definitive Endoderm Generated from Human Embryonic Stem Cells Depends on the Differential Signaling of Retinoic Acid, Wnt-, and BMP-Signaling

Stem Cells ◽  
2016 ◽  
Vol 34 (11) ◽  
pp. 2635-2647 ◽  
Author(s):  
Claudia Davenport ◽  
Ulf Diekmann ◽  
Insa Budde ◽  
Nora Detering ◽  
Ortwin Naujok
Keyword(s):  
Stem Cells ◽  
Retinoic Acid ◽  
Embryonic Stem Cells ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Definitive Endoderm ◽  
Bmp Signaling ◽  
Differential Signaling ◽  
Anterior Posterior

scholarly journals Epigenetic modification of retinoic acid-treated human embryonic stem cells

BMB Reports ◽  
2010 ◽  
Vol 43 (12) ◽  
pp. 830-835 ◽  
Author(s):  
Hyun-Sub Cheong ◽  
Han-Chul Lee ◽  
Byung-Lae Park ◽  
Hye-Min Kim ◽  
Mi-Jin Jang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Retinoic Acid ◽  
Embryonic Stem Cells ◽  
Human Embryonic Stem Cells ◽  
Epigenetic Modification ◽  
Embryonic Stem

Retinoic acid dependent histone 3 demethylation of the clustered HOX genes during neural differentiation of human embryonic stem cells

2013 ◽  
Vol 91 (2) ◽  
pp. 116-122 ◽  
Author(s):  
Maryam Shahhoseini ◽  
Zeinab Taghizadeh ◽  
Maryam Hatami ◽  
Hossein Baharvand
Keyword(s):  
Stem Cells ◽  
Retinoic Acid ◽  
Embryonic Stem Cells ◽  
Human Embryonic Stem Cells ◽  
Epigenetic Regulation ◽  
Neural Differentiation ◽  
Hox Genes ◽  
Embryonic Stem ◽  
Model Systems ◽  
Hox Clusters

Gene activation of HOX clusters is an early event in embryonic development. These genes are highly expressed and active in the vertebrate nervous system. Based on the presence of retinoic acid response elements (RAREs) in the regulatory region of many of the HOX genes, it is deduced that retinoic acid (RA) can influence epigenetic regulation and consequently the expression pattern of HOX during RA-induced differentiation of embryonic model systems. In this investigation, the expression level as well as the epigenetic regulation of several HOX genes of the 4 A–D clusters was analyzed in human embryonic stem cells, and also through their neural induction, in the presence and absence of RA. Expression analysis data significantly showed increased mRNA levels of all examined HOX genes in the presence of RA. Epigenetic analysis of the HOX gene regulatory regions also showed a significant decrease in methylation of histone H3K27 parallel to an absolute preferential incorporation of the demethylase UTX rather than JMJD3 in RA-induced neural differentiated cells. This finding clearly showed the functional role of UTX in epigenetic alteration of HOX clusters during RA-induced neural differentiation; the activity could not be detectable for the demethylase JMJD3 during this developmental process.

Retinoic Acid Enhances Skeletal Myogenesis in Human Embryonic Stem Cells by Expanding the Premyogenic Progenitor Population

2011 ◽  
Vol 8 (2) ◽  
pp. 482-493 ◽  
Author(s):  
Tammy Ryan ◽  
Jun Liu ◽  
Alphonse Chu ◽  
Lisheng Wang ◽  
Alexandre Blais ◽  
...  
Keyword(s):  
Stem Cells ◽  
Retinoic Acid ◽  
Embryonic Stem Cells ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Skeletal Myogenesis

scholarly journals Efficient Derivation of Human Neuronal Progenitors and Neurons from Pluripotent Human Embryonic Stem Cells with Small Molecule Induction

10.3791/3273 ◽  
2011 ◽  
Author(s):  
Xuejun H. Parsons ◽  
Yang D. Teng ◽  
James F. Parsons ◽  
Evan Y. Snyder ◽  
David B. Smotrich ◽  
...  
Keyword(s):  
Stem Cells ◽  
Embryonic Stem Cells ◽  
Small Molecule ◽  
Human Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Neuronal Progenitors

scholarly journals CHIR99021 combined with retinoic acid promotes the differentiation of primordial germ cells from human embryonic stem cells

Oncotarget ◽  
2016 ◽  
Vol 8 (5) ◽  
pp. 7814-7826 ◽  
Author(s):  
Tingting Cheng ◽  
Kui Zhai ◽  
Yan Chang ◽  
Guidong Yao ◽  
Jiahuan He ◽  
...  
Keyword(s):  
Stem Cells ◽  
Retinoic Acid ◽  
Embryonic Stem Cells ◽  
Human Embryonic Stem Cells ◽  
Germ Cells ◽  
Primordial Germ Cells ◽  
Embryonic Stem
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