Multiple substance use among heroin-dependent patients before and during attendance at methadone maintenance treatment program, Yunnan, China

2011 ◽  
Vol 116 (1-3) ◽  
pp. 246-249 ◽  
Author(s):  
Lei Li ◽  
Rassamee Sangthong ◽  
Virasakdi Chongsuvivatwong ◽  
Edward McNeil ◽  
Jianhua Li
Keyword(s):  
Substance Use ◽  
Treatment Program ◽  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Methadone Maintenance Treatment Program ◽  
Multiple Substance

scholarly journals Moving toward Personalized Medicine in the Methadone Maintenance Treatment Program: A Pilot Study on the Evaluation of Treatment Responses in Taiwan

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Hsin-Ya Lee ◽  
Jih-Heng Li ◽  
Yuh-Ling Sheu ◽  
Hsin-Pei Tang ◽  
Wei-Chiao Chang ◽  
...  
Keyword(s):  
Substance Use ◽  
Pilot Study ◽  
Personalized Medicine ◽  
Treatment Program ◽  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Alcohol Problems ◽  
Methadone Maintenance Treatment Program ◽  
Treatment Responses

This pilot study simultaneously evaluated the effects of various factors, including genetic variations ofCYP2B6,CYP2C19, andABCB1, demographic characteristics, disease states, methadone-drug interactions (MDIs), and poly-substance use, on the treatment responses among non-HIV patients in the methadone maintenance treatment program (MMTP) in Taiwan. A total of 178 patients were recruited from two major hospitals that provided MMTP services in southern Taiwan, and information regarding concomitant medications and diseases was acquired from the National Health Insurance (NHI) program. The results demonstrated that the methadone maintenance dose,CYP2B6785G allele, andABCB12677T allele have positive effects on the methadone plasma concentration. In contrast, patients with HCV coinfection, alcohol problems, and psychiatric diseases may have a negative response to treatment. Thus, a comprehensive evaluation of treatment responses in the MMTP should include not only genetic polymorphisms in methadone metabolism and transporter proteins, but also concomitant diseases, MDIs, and poly-substance use. The results also suggest that personalized medicine may be indispensable for a better outcome of the MMTP.

scholarly journals HCV and HIV Infection among Heroin Abusers in a Methadone Maintenance Treatment Program

Health ◽  
2016 ◽  
Vol 08 (12) ◽  
pp. 1209-1222
Author(s):  
Yi-Chieh Lee ◽  
Jian-Kang Chao ◽  
Ming-Der Shi ◽  
Mi-Chia Ma ◽  
I-Chen Chao
Keyword(s):  
Hiv Infection ◽  
Treatment Program ◽  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Methadone Maintenance ◽  
Methadone Maintenance Treatment Program ◽  
Heroin Abusers

scholarly journals Faktor-Faktor yang Mempengaruhi Pengguna Napza Suntik dalam Tindakan Pemanfaatan Layanan Program Terapi Rumatan Methadon (PTRM) di Kota Cirebon

2016 ◽  
Vol 11 (2) ◽  
pp. 18
Author(s):  
Dessy Aryanti ◽  
Bagoes Widjanarko ◽  
Kusyogo Cahyo
Keyword(s):  
Drug Use ◽  
Harm Reduction ◽  
Treatment Program ◽  
Methadone Maintenance Treatment ◽  
Maintenance Treatment ◽  
Health Workers ◽  
Methadone Maintenance ◽  
Family Attitudes ◽  
Methadone Maintenance Treatment Program ◽  
Hiv Aids

ABSTRACTAccording to the risk factors as a result of injecting drug use (IDU) were second highest, after the heterosexual and homo-bisexual. In IDUs face two risks for contracting HIV / AIDS, from the use of unsterilized needles and performed together or alternately with other IDUs and also through sexual intercourse, especially that done with more than one partner without using a condom. Methadone maintenance treatment program (PTRM) is included in the Harm Reduction program – This is a program of harm reduction drug use in preventing transmission of HIV / AIDS. This research is quantitative with correlational design, sampling using the technique across sectional the total population 50 person IDUs of injecting drug users in the city of Cirebon -use structured questionnaires technique. From the 50 IDUs who were respondents in this research note that 68% did not use PTRM services. It is because most IDUs still can not stop using injection drugs and have not been willing to switch to PTRM. Results of univariate analysis to determine the level of knowledge of IDUs about PTRM 88% have a good category, the attitude of the respondents 80% have category support PTRM, family attitudes 50% have category support PTRM, attitudes of peers 72% have a category does not support the utilizations PTRM, attitude of health workers 66% category does not support PTRM, and the availability of facilities and health facilities 52% support in PTRM services. For the bivariate analysis showed that the attitude of IDUs to program substitution therapy methadone-related measures the utilization of PTRM, whereas knowledge factors, family attitudes, attitudes of peers, attitude of health workers, and the availability of facilities. Then knowledge of IDUs about PTRM shows no relationship with the actions the utilization of PTRM , And based on multivariate analysis known that the action the utilization of PTRM is influenced by the family attitudes were supportive of the utilizations of Methadone maintenance treatment program (PTRM).Keywords: drug, injection, PTRM, HIV/AIDS

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