Facile synthesis of carbon dots derived from ampicillin sodium for live/dead microbe differentiation, bioimaging and high selectivity detection of 2,4-dinitrophenol and Hg(II)

2020 ◽  
Vol 175 ◽  
pp. 108187 ◽  
Author(s):  
Xiaotian Yuan ◽  
Yujiao Tu ◽  
Wei Chen ◽  
Zhiwei Xu ◽  
Yunlin Wei ◽  
...  
2021 ◽  
Vol 175 ◽  
pp. 516-525
Author(s):  
Lan Sun ◽  
Zhenye Mo ◽  
Qiong Li ◽  
Dafeng Zheng ◽  
Xueqing Qiu ◽  
...  

2014 ◽  
Vol 525 ◽  
pp. 93-96
Author(s):  
Wei Shi ◽  
Ji Ming Zhang ◽  
Jian Hua Zhou ◽  
Jian Hua Zhou ◽  
Song Song Ding

Herein we describle a facile synthesis of sulphonic acid oxime esters in acetonitrile from the corresponding sulphonic acids and oximes catalyzed by the environmental friendly 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) in the presence of triethylamine (TEA) under mild conditions. The present approach offers the advantages of a clean reaction, simple methodology, employing readily available catalyst, short reaction duration, high selectivity and high yield.


Author(s):  
Chang Liu ◽  
Hongying Li ◽  
Rui Cheng ◽  
Jiazhuang Guo ◽  
Guo-Xing Li ◽  
...  

2017 ◽  
Vol 46 (36) ◽  
pp. 12306-12312 ◽  
Author(s):  
Yunxiao Zhang ◽  
Tao Cai ◽  
Wangji Shang ◽  
Dan Liu ◽  
Qiang Guo ◽  
...  

An inorganic-organic carbon dots consisting of an ionic liquid moiety inserted in the carbon skeleton has been synthesized and verified to be a high-performance anti-wear and friction-reducing lubricant additives in poly(ethylene glycol)(PEG).


2018 ◽  
Vol 1042 ◽  
pp. 125-132 ◽  
Author(s):  
Yuan Jiao ◽  
Xiaojuan Gong ◽  
Hui Han ◽  
Yifang Gao ◽  
Wenjing Lu ◽  
...  

2020 ◽  
Author(s):  
Jinming Guan ◽  
Christina Spry ◽  
Erick T. Tjhin ◽  
Penghui Yang ◽  
Tanakorn Kittikool ◽  
...  

ABSTRACTThe Plasmodium parasites that cause malaria are adept at developing resistance to antimalarial drugs, necessitating the search for new antiplasmodials. Although several amide analogs of pantothenate (pantothenamides) show potent antiplasmodial activity, hydrolysis by pantetheinases (or vanins) present in blood rapidly inactivates them. We report herein the facile synthesis and biological activity of a small library of pantothenamide analogs in which the labile amide group is replaced with a variety of heteroaromatic rings. Several of the new analogs display antiplasmodial activity in the nanomolar range against P. falciparum and/or P. knowlesi in the presence of pantetheinase. A previously reported triazole and an isoxazole derivative presented here were further characterized and found to possess high selectivity indices, medium or high Caco-2 permeability, and medium or low microsomal clearance in vitro. Although we show here that the two compounds fail to suppress proliferation of P. berghei in vivo, pharmacokinetic and contact time data presented provide a benchmark for the compound profile required to achieve antiplasmodial activity in mice and should facilitate lead optimization.


2018 ◽  
Vol 8 (5) ◽  
pp. 1189-1196 ◽  
Author(s):  
Lin Jin ◽  
Jingguo Li ◽  
Liyun Liu ◽  
Zhenling Wang ◽  
Xingcai Zhang
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