Eco-Friendly Synthesis of Sulphonic Acid Oxime Esters Catalyzed by 2-(1H-Benzotriazole-1-yl)-1,1,3,3-Tetramethyluronium Tetrafluoroborate

2014 ◽  
Vol 525 ◽  
pp. 93-96
Author(s):  
Wei Shi ◽  
Ji Ming Zhang ◽  
Jian Hua Zhou ◽  
Jian Hua Zhou ◽  
Song Song Ding
Keyword(s):  
High Selectivity ◽  
Sulphonic Acid ◽  
Present Approach ◽  
High Yield ◽  
Facile Synthesis ◽  
Reaction Duration ◽  
Mild Conditions ◽  
Environmental Friendly

Herein we describle a facile synthesis of sulphonic acid oxime esters in acetonitrile from the corresponding sulphonic acids and oximes catalyzed by the environmental friendly 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) in the presence of triethylamine (TEA) under mild conditions. The present approach offers the advantages of a clean reaction, simple methodology, employing readily available catalyst, short reaction duration, high selectivity and high yield.

Facile synthesis of furfuryl ethyl ether in high yield via the reductive etherification of furfural in ethanol over Pd/C under mild conditions

2018 ◽  
Vol 20 (9) ◽  
pp. 2110-2117 ◽  
Author(s):  
Yun Wang ◽  
Qianqian Cui ◽  
Yejun Guan ◽  
Peng Wu
Keyword(s):  
Ethyl Ether ◽  
High Yield ◽  
Facile Synthesis ◽  
Mild Conditions

Furfuryl ethyl ether (FEE) was synthesized from furfural via reductive etherification in 81% yield over a Pd/C catalyst under mild conditions.

Reaction of CO2 and CS2 with Aniline Catalyzed by AlCl3 under Mild Condition

2013 ◽  
Vol 575-576 ◽  
pp. 531-534 ◽  
Author(s):  
Hong Xing Xu ◽  
Xin Hua Yuan
Keyword(s):  
Electrophilic Substitution ◽  
Room Temperature ◽  
High Selectivity ◽  
High Yield ◽  
Ambient Atmosphere ◽  
Reaction Products ◽  
Element Analysis ◽  
H Nmr ◽  
Mild Conditions ◽  
Nmr Data

The reactions of aniline with CO2and CS2were investigated in the presence of sublimed AlCl3under the mild conditions (room temperature and ambient atmosphere). Reasonable mechanism, electrophilic substitution of carbonium and nitronium, was also provided according to GC/MS analysis of the reaction products. The resulting N,N-diphenylurea (DPU, high selectivity of 92.5mol%) and N,N-diphenyl thiourea (DPTU, high yield and selectivity of 80.1mol% and 99.7mol%, respectively) were purified by recrystallizing from ethanol and identified by melting point, element analysis, GC/MS, FTIR, UV and1H NMR data.

Facile Synthesis of a Diverse Library of Mono-3-substituted β-Cyclodextrin Analogues

2018 ◽  
Author(s):  
Kathryn Kellett ◽  
Brendan M. Duggan ◽  
Michael Gilson
Keyword(s):  
High Yield ◽  
Facile Synthesis ◽  
Wide Range

We have described simple, high-yield, protocols, which require only commonly accessible equipment, to synthesize a wide range of β-CD derivatives mono-substituted at the secondary face. These derivatives may be useful in their own right, and they are also scaffolds for further modification, and examples of the far broader array of derivatives that may be accessed by these procedures.

4-Hydroxy Pyridinium Triflate@SiO2 Nanoparticles as a Novel Efficient Catalyst for Fries Rearrangement of Aryl Esters with High Selectivity

2020 ◽  
Vol 17 (8) ◽  
pp. 654-660
Author(s):  
Shermineh Sadat Ghalehbandi ◽  
Dadkhoda Ghazanfari ◽  
Sayed Ali Ahmadi ◽  
Enayatollah Sheikhhosseini
Keyword(s):  
High Selectivity ◽  
Sio2 Nanoparticles ◽  
High Yield ◽  
Synthetic Method ◽  
Functionalized Silica ◽  
Efficient Catalyst ◽  
Fries Rearrangement ◽  
Free Condition ◽  
Solvent Free Condition ◽  
Work Up

Introduction: We developed a simple, fast and new method for the Fries rearrangement of aryl esters. Materials and Methods: 4-Hydroxy pyridinium triflate functionalized silica is a very efficient, reusable and economically available catalyst for the Fries rearrangement in solvent-free condition and under microwave irradiation. Results and Discussion: Also, a notable selectivity was observed in the presence of 4-hydroxy pyridinium triflate functionalized silica. Conclusion: Selectivity, shorter reaction time, high yield, and easy work-up are advantages of this synthetic method.

Facile Synthesis of Tribenzosilepins from Terphenyls and Dihydrosilanes by Electrophilic Double Silylation

2021 ◽  
Author(s):  
Yafang Dong ◽  
Kohei Sekine ◽  
Yoichiro Kuninobu
Keyword(s):  
Reaction System ◽  
High Yield ◽  
Facile Synthesis

Tribenzosilepins were synthesized from terphenyls and dihydrosilanes using a facile approach using a double sila-Friedel–Crafts reaction. Several silepin derivatives were obtained in moderate to high yield. The reaction system was...

Selection of high-quality sperm with thousands of parallel channels

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Mohammad Simchi ◽  
Jason Riordon ◽  
Jae Bem You ◽  
Yihe Wang ◽  
Sa Xiao ◽  
...  
Keyword(s):  
Clinical Practice ◽  
High Selectivity ◽  
High Yield ◽  
Sperm Selection ◽  
High Quality ◽  
Parallel Channels ◽  
Selection Of

A 3D-structured sperm selection device is presented that achieves both high selectivity and high yield via thousands of parallel channels. The device significantly outperforms the best clinical practice by selecting ∼100 000 of higher-quality sperm.

Facile synthesis of 5-hydroxymethylfurfural: a sustainable raw material for the synthesis of key intermediates toward 21,23-dioxaporphyrins

RSC Advances ◽  
2015 ◽  
Vol 5 (121) ◽  
pp. 100401-100407 ◽  
Author(s):  
Rajamani Rajmohan ◽  
Subramaniyan Gayathri ◽  
Pothiappan Vairaprakash
Keyword(s):  
Room Temperature ◽  
Solid Support ◽  
Raw Material ◽  
Facile Synthesis ◽  
Mild Conditions

In a simple and conceptually designed method for the dehydration of fructose on a solid support, 5-hydroxymethylfurfural (HMF) was synthesized in more than 95% isolated yield from fructose under very mild conditions at room temperature.

Regioselective 1,4-conjugate aza-Michael addition of dienones with benzotriazole

2017 ◽  
Vol 23 (4) ◽  
Author(s):  
Zheng Li ◽  
Tianpeng Li ◽  
Rugang Fu ◽  
Jingya Yang
Keyword(s):  
Transition Metal ◽  
Michael Addition ◽  
Potassium Acetate ◽  
High Yield ◽  
Metal Free ◽  
Mild Conditions

AbstractThe regioselective 1,4-conjugate aza-Michael addition of dienones with benzotriazole catalyzed by potassium acetate is described. A series of 3-(benzotriazol-1-yl)-1,5-diarylpent-4-en-1-ones were efficiently synthesized under mild conditions. This protocol has advantages of transition-metal free catalyst, high yield and high regioselectivity.

scholarly journals High yield accelerated reactions in nonvolatile microthin films: chemical derivatization for analysis of single-cell intracellular fluid

2018 ◽  
Vol 9 (40) ◽  
pp. 7779-7786 ◽  
Author(s):  
Zhenwei Wei ◽  
Xiaochao Zhang ◽  
Jinyu Wang ◽  
Sichun Zhang ◽  
Xinrong Zhang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Single Cell ◽  
Individual Cell ◽  
High Yield ◽  
Chemical Derivatization ◽  
Intracellular Fluid ◽  
Mild Conditions ◽  
Successful Analysis ◽  
Trace Components

The identification of trace components from an individual cell can require derivatization under mild conditions for successful analysis by mass spectrometry (MS).

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