scholarly journals Memory-Focused Cognitive Therapy for Cocaine Use Disorder: Theory, Procedures and Preliminary Evidence From an External Pilot Randomised Controlled Trial

EBioMedicine ◽  
2018 ◽  
Vol 29 ◽  
pp. 177-189 ◽  
Author(s):  
John Marsden ◽  
Camille Goetz ◽  
Tim Meynen ◽  
Luke Mitcheson ◽  
Garry Stillwell ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Cognitive Therapy ◽  
Controlled Trial ◽  
Preliminary Evidence ◽  
Pilot Randomised Controlled Trial ◽  
Cocaine Use ◽  
Randomised Controlled

scholarly journals Online Social anxiety Cognitive therapy for Adolescents (OSCA): protocol for a randomised controlled trial

Trials ◽  
2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Eleanor Leigh ◽  
David M. Clark
Keyword(s):  
Randomised Controlled Trial ◽  
Social Anxiety ◽  
Cognitive Therapy ◽  
Controlled Trial ◽  
Large Population ◽  
Preliminary Evidence ◽  
Anxiety Symptoms ◽  
General Anxiety ◽  
Face To Face ◽  
Randomised Controlled

Abstract Background Adolescent social anxiety disorder (SAD) is common, impairing and persistent. There is a need to intervene early to avert its long-term consequences. Cognitive Therapy for SAD is the leading treatment for adults and shows promise for adolescents. However, given the scale of the problem of adolescent SAD and the limited availability of psychological therapists in child and adolescent mental health services, there is a substantial gap in service provision. Delivering therapy via the Internet may provide part of the solution to this problem. An Internet version of adult Cognitive Therapy for SAD has been developed, with outcomes similar to face-to-face therapy. We have recently adapted this treatment for use with adolescents with SAD. Here, we describe a randomised controlled trial designed to test the efficacy of Internet Cognitive Therapy for adolescent SAD compared to waitlist. Methods/design Forty adolescents aged 14–18 years with a diagnosis of SAD will be recruited via schools. Participants will be randomly allocated to Internet Cognitive Therapy or to waitlist. All participants will be assessed three times during the study—at baseline (pretreatment/wait), midtreatment/wait (week 8) and posttreatment/wait (week 15). Participants in the experimental arm will also complete weekly measures as part of the online program and they will be assessed at 3 and 6 months. Postwait, participants in the waitlist arm will be offered Internet Cognitive Therapy, and weekly and posttreatment data will also be collected for them. The trial aims to test whether Internet Cognitive Therapy is superior to waitlist in reducing social anxiety symptoms and in reducing the proportion of adolescents meeting criteria for SAD. Other outcomes of interest include depression and general anxiety symptoms. Acceptability of the online treatment will also be evaluated. Discussion This randomised controlled trial will provide preliminary evidence on whether this intervention, requiring relatively low levels of therapist input, is safe and clinically effective. If this is shown to be the case, Internet Cognitive Therapy for adolescents has the potential to provide a service to the large population of adolescents with untreated SAD. Trial registration ISRCTN Registry, ISRCTN15079139. Version 1 registered on 06/02/2019.

scholarly journals Cognitive therapy for internalised stigma in people experiencing psychosis: A pilot randomised controlled trial

2016 ◽  
Vol 240 ◽  
pp. 96-102 ◽  
Author(s):  
Anthony P. Morrison ◽  
Eilish Burke ◽  
Elizabeth Murphy ◽  
Melissa Pyle ◽  
Samantha Bowe ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Cognitive Therapy ◽  
Controlled Trial ◽  
Pilot Randomised Controlled Trial ◽  
Randomised Controlled

scholarly journals Online Social anxiety Cognitive therapy for Adolescents (OSCA): a randomised controlled trial

2019 ◽  
Author(s):  
Eleanor Leigh ◽  
David M Clark
Keyword(s):  
Randomised Controlled Trial ◽  
Social Anxiety ◽  
Cognitive Therapy ◽  
Controlled Trial ◽  
Large Population ◽  
Preliminary Evidence ◽  
Anxiety Symptoms ◽  
General Anxiety ◽  
Face To Face ◽  
Randomised Controlled

Abstract Background Adolescent social anxiety disorder (SAD) is common, impairing and persistent. There is a need to intervene early to avert its long-term consequences. Cognitive Therapy for SAD is the leading treatment for adults and shows promise for adolescents. However, given the scale of the problem of adolescent SAD and the limited availability of psychological therapists in child and adolescent mental health services, there is a substantial gap in service provision. Delivering therapy via the Internet may provide part of the solution to this problem. An Internet version of adult Cognitive Therapy for SAD has been developed, with outcomes similar to face-to-face therapy. We have recently adapted this treatment for use with adolescents with SAD. Here, we describe a randomised controlled trial designed to test the efficacy of Internet Cognitive Therapy for adolescent SAD compared to waitlist. Methods and Design Forty adolescents aged 14-18 years old with a diagnosis of SAD will be recruited via schools. Participants will be randomly allocated to Internet Cognitive Therapy or to waitlist. All participants will be assessed three times during the study – at baseline (pretreatment/wait), midtreatment/wait (week 8), and at posttreatment/wait (week 15). Participants in the experimental arm will also complete weekly measures as part of the online program and they will be assessed at 3 and 6 months follow-up. Postwait, participants in the waitlist arm will be offered Internet Cognitive Therapy, and weekly and posttreatment data will also be collected for them. The trial aims to test whether Internet Cognitive Therapy is superior to waitlist in reducing social anxiety symptoms and in reducing the proportion of adolescents meeting criteria for SAD. Other outcomes of interest include depression and general anxiety symptoms. Acceptability of the online treatment will also be evaluated. Discussion This RCT will provide preliminary evidence on whether this intervention, requiring relatively low levels of therapist input, is safe and clinically effective. If this is shown to be the case, Internet Cognitive Therapy for adolescents has the potential to provide a service to the large population of adolescents with untreated SAD.

scholarly journals Protocol for a pilot randomised controlled trial of mindfulness-based cognitive therapy in youth with inflammatory bowel disease and depression

BMJ Open ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. e025568 ◽  
Author(s):  
Tatjana Ewais ◽  
Jake Begun ◽  
Maura Kenny ◽  
Kai-Hsiang Chuang ◽  
Johanna Barclay ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Randomised Controlled Trial ◽  
Cognitive Therapy ◽  
Bowel Disease ◽  
Age Of Onset ◽  
Controlled Trial ◽  
Pilot Randomised Controlled Trial ◽  
Inflammatory Bowel ◽  
Therapy Completion ◽  
Randomised Controlled

IntroductionInflammatory bowel disease (IBD) is a chronic autoinflammatory disease of the gastrointestinal tract with peak age of onset during adolescence and young adulthood. Adolescents and young adults (AYAs) with IBD experience higher depression rates compared with peers who are well or have other chronic conditions. Mindfulness-based interventions are of particular interest because of their potential to improve both the course of IBD and depression.Methods and analysisThis study is a parallel design, single-blind, pilot randomised controlled trial (RCT) of mindfulness-based cognitive therapy (MBCT) in AYAs with IBD and depression. The trial aims to recruit 64 participants who will be randomly allocated to MBCT or treatment as usual. The primary outcome measure is the depression subscale score from the Depression, Anxiety and Stress Scale. Secondary outcomes include anxiety, stress, post-traumatic growth, IBD-related quality of life, illness knowledge, medication adherence, mindfulness, IBD activity, inflammatory markers, microbiome and brain neuroconnectivity changes. All outcomes other than neuroimaging will be collected at three time points: at baseline, at therapy completion and at 20 weeks. Neuroimaging will be conducted at baseline and at therapy completion. Mixed-effects linear and logistic regression modelling will be used to analyse continuous and dichotomous outcomes, respectively. Participants’ experiences will be explored through focus groups, and thematic analysis will be used to generate relevant themes.Ethics and disseminationThe protocol has been approved by the Mater Hospital Human Research Ethics Committee (HREC) and University of Queensland HREC. Trial findings will be published in peer-reviewed journals and will be presented at scientific conferences.Trial registration numberACTRN12617000876392, U1111-1197-7370; Pre-results.

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