scholarly journals Evaluation of the association of single nucleotide polymorphisms in DDP4 and CDK5RAP2 genes with rheumatoid arthritis susceptibility in Iranian population

2018 ◽  
Vol 19 (3) ◽  
pp. 185-189 ◽  
Author(s):  
Zahra Malekshahi ◽  
Mahdi Mahmoudi ◽  
Massoomeh Akhlaghi ◽  
Masoud Garshasbi ◽  
Ahmadreza Jamshidi ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Iranian Population ◽  
Rheumatoid Arthritis Susceptibility ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Arthritis Susceptibility

IL27 gene single nucleotide polymorphisms confer susceptibility to rheumatoid arthritis in Iranian population

Meta Gene ◽  
2018 ◽  
Vol 18 ◽  
pp. 149-152 ◽  
Author(s):  
Sahar Anaraki Mohammadi ◽  
Reza Mansouri ◽  
Abbas Shahi ◽  
Massoumeh Akhlaghi ◽  
Navid Dashti ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Iranian Population ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population

2000 ◽  
Vol 106 (3) ◽  
pp. 293-297 ◽  
Author(s):  
Y. Ohnishi ◽  
K. Suematsu ◽  
M. Minami ◽  
T. Seki ◽  
M. Yukioka ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Candidate Genes ◽  
Japanese Population ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Distribution and genotype frequency of adiponectin (+45 T/G) and adiponectin receptor2 (+795 G/A) single nucleotide polymorphisms in Iranian population

Gene ◽  
2011 ◽  
Vol 486 (1-2) ◽  
pp. 97-103 ◽  
Author(s):  
Fatemeh Namvaran ◽  
Negar Azarpira ◽  
Bita Geramizadeh ◽  
Parvaneh Rahimi-Moghaddam
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Iranian Population ◽  
Genotype Frequency ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Association of Single Nucleotide Polymorphisms of PADI4 and HLA-DRB1 Alleles with Susceptibility to Rheumatoid Arthritis-Related Lung Diseases

Lung ◽  
2016 ◽  
Vol 194 (5) ◽  
pp. 745-753 ◽  
Author(s):  
Seung Taek Song ◽  
Song Soo Kim ◽  
Ji Young Kim ◽  
So Young Lee ◽  
Kwangwoo Kim ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Lung Diseases ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

scholarly journals Functional implications of single nucleotide polymorphisms rs662 and rs854860 on the antioxidative activity of paraoxonase1 (PON1) in patients with rheumatoid arthritis

2018 ◽  
Vol 38 (5) ◽  
pp. 1329-1337 ◽  
Author(s):  
Arkaitz Mucientes ◽  
Benjamín Fernández-Gutiérrez ◽  
Eva Herranz ◽  
Luis Rodriguez-Rodriguez ◽  
Jezabel Varadé ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Antioxidative Activity ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Functional Implications

scholarly journals Susceptibility of the Iranian population to severe acute respiratory syndrome coronavirus 2 infection based on variants of angiotensin I converting enzyme 2

2020 ◽  
Vol 15 (8) ◽  
pp. 507-514
Author(s):  
Alireza Mohebbi ◽  
Fatemeh Sana Askari ◽  
Mohsen Ebrahimi ◽  
Mana Zakeri ◽  
Mohammad Yasaghi ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Single Nucleotide Polymorphisms ◽  
Resistance Mutation ◽  
Iranian Population ◽  
Natural Resistance ◽  
Missense Mutations ◽  
Nucleotide Polymorphisms ◽  
Converting Enzyme ◽  
Viral Glycoprotein ◽  
Single Nucleotide

Background: Variations in the viral receptor human angiotensin-converting enzyme 2 (ACE2) may specify the susceptibility of a certain population to severe acute respiratory syndrome coronavirus 2. Objective: Evaluation of the affinity of severe acute respiratory syndrome coronavirus 2 spike glycoprotein to the Iranian genetic variants of ACE2. Materials & methods: Single nucleotide polymorphisms of ACE2 among the Iranian population were collected from the Iranome database. Missense mutations in the N-terminal peptidase domain were selected for in silico analysis. Results: 17 missense single nucleotide polymorphisms were found at ACE2. Viral glycoprotein had the lowest affinity to ACE2 mutant V485L. Discussion: The V485L variant of ACE2 could be a natural resistance mutation among the Iranian population. In addition, variant S331F can increase slightly the susceptibility to infection with the virus.

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