scholarly journals Association between single-nucleotide polymorphisms in theSEC8L1 gene, which encodes a subunit of the exocyst complex, and rheumatoid arthritis in a Japanese population

2005 ◽  
Vol 52 (5) ◽  
pp. 1371-1380 ◽  
Author(s):  
Daisuke Hamada ◽  
Yoichiro Takata ◽  
Dai Osabe ◽  
Kyoko Nomura ◽  
Syuichi Shinohara ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Japanese Population ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Exocyst Complex ◽  
A Subunit

Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population

2000 ◽  
Vol 106 (3) ◽  
pp. 293-297 ◽  
Author(s):  
Y. Ohnishi ◽  
K. Suematsu ◽  
M. Minami ◽  
T. Seki ◽  
M. Yukioka ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Candidate Genes ◽  
Japanese Population ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Identification of 142 single nucleotide polymorphisms in 41 candidate genes for rheumatoid arthritis in the Japanese population

2000 ◽  
Vol 106 (3) ◽  
pp. 293-297 ◽  
Author(s):  
R. Yamada ◽  
T. Tanaka ◽  
Y. Ohnishi ◽  
K. Suematsu ◽  
M. Minami ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Candidate Genes ◽  
Japanese Population ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Twenty­six Novel Single Nucleotide Polymorphisms and their Frequencies of the NR1I3(CAR) Gene in a Japanese Population

2003 ◽  
Vol 18 (6) ◽  
pp. 413-418 ◽  
Author(s):  
Shinobu Ikeda ◽  
Kouichi Kurose ◽  
Shogo Ozawa ◽  
Kimie Sai ◽  
Ryuichi Hasegawa ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Japanese Population ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Association of body mass index-related single nucleotide polymorphisms with psychiatric disease and memory performance in a Japanese population

2016 ◽  
Vol 29 (5) ◽  
pp. 299-308 ◽  
Author(s):  
Midori Ninomiya-Baba ◽  
Junko Matsuo ◽  
Daimei Sasayama ◽  
Hiroaki Hori ◽  
Toshiya Teraishi ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Single Nucleotide Polymorphisms ◽  
Japanese Population ◽  
Memory Performance ◽  
Psychiatric Disease ◽  
Psychiatric Diseases ◽  
Healthy Controls ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Poor Memory

ObjectiveObesity is a risk factor for psychiatric diseases. Recently, a number of single nucleotide polymorphisms (SNPs) have been shown to be related to body mass index (BMI). In this study, we investigated the association of BMI-related SNPs with psychiatric diseases and one of their endophenotypes, memory performance, in a Japanese population.MethodsThe subjects were 1624 patients with one of three psychiatric diseases (799 patients with major depressive disorder, 594 with schizophrenia, and 231 with bipolar disorder) and 1189 healthy controls. Memory performance was assessed using the Wechsler Memory Scale – Revised (WMS-R). Genomic DNA was prepared from venous blood and used to genotype 23 BMI-related SNPs using the TaqMan 5′-exonuclease allelic discrimination assay. We then analysed the relationships between the SNPs and psychiatric disease and various subscales of the WMS-R.ResultsThree SNPs (rs11142387, rs12597579, and rs6548238) showed significant differences in the genotype or allele frequency between patients with any psychiatric diseases and controls. Furthermore, six SNPs (rs11142387, rs12597579, rs2815752, rs2074356, rs4776970, and rs2287019) showed significant differences in at least one subscale of the WMS-R depending on the genotypes of the healthy controls. Interestingly, rs11142387 near the Kruppel-like factor 9 (KLF9) was significantly associated with psychiatric disease and poor memory function.ConclusionsWe identified three and six BMI-related SNPs associated with psychiatric disease and memory performance, respectively. In particular, carrying the A allele of rs11142387 near KLF9 was found to be associated with psychiatric disease and poor memory performance, which warrants further investigations.

Association of Single Nucleotide Polymorphisms of PADI4 and HLA-DRB1 Alleles with Susceptibility to Rheumatoid Arthritis-Related Lung Diseases

Lung ◽  
2016 ◽  
Vol 194 (5) ◽  
pp. 745-753 ◽  
Author(s):  
Seung Taek Song ◽  
Song Soo Kim ◽  
Ji Young Kim ◽  
So Young Lee ◽  
Kwangwoo Kim ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Lung Diseases ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

scholarly journals Functional implications of single nucleotide polymorphisms rs662 and rs854860 on the antioxidative activity of paraoxonase1 (PON1) in patients with rheumatoid arthritis

2018 ◽  
Vol 38 (5) ◽  
pp. 1329-1337 ◽  
Author(s):  
Arkaitz Mucientes ◽  
Benjamín Fernández-Gutiérrez ◽  
Eva Herranz ◽  
Luis Rodriguez-Rodriguez ◽  
Jezabel Varadé ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Single Nucleotide Polymorphisms ◽  
Antioxidative Activity ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Functional Implications
Sign in / Sign up

Export Citation Format

Share Document