scholarly journals Definition of the margin of major coronary artery bifurcations during radiotherapy with electrocardiograph-gated 4D-CT

2018 ◽  
Vol 49 ◽  
pp. 90-94 ◽  
Author(s):  
Qian Li ◽  
Ying Tong ◽  
Yong Yin ◽  
Pinjing Cheng ◽  
Guanzhong Gong
Keyword(s):  
Coronary Artery ◽  
4D Ct ◽  
Major Coronary Artery ◽  
Definition Of

scholarly journals Detection of major coronary artery anomalies in a pediatric and adult population: A prospective echocardiographic study

2013 ◽  
Vol 106 (8-9) ◽  
pp. 467
Author(s):  
F. Labombarda ◽  
G. Coutance ◽  
C. Mery ◽  
A. Hodzic ◽  
P. Dupont-Chauvet ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Adult Population ◽  
Coronary Artery Anomalies ◽  
Echocardiographic Study ◽  
Major Coronary Artery

Effects of Defibrillation Shocks Delivered Directly Over a Major Coronary Artery

1992 ◽  
Vol 15 (11) ◽  
pp. 1711-1719 ◽  
Author(s):  
S. DEBORAH LUCY ◽  
DOUGLAS L. JONES ◽  
GEORGE J. KLEIN
Keyword(s):  
Coronary Artery ◽  
Major Coronary Artery

Fast CT-FFR Analysis Method for the Coronary Artery Based on 4D-CT Image Analysis and Structural and Fluid Analysis

2015 ◽  
Author(s):  
Mitsuaki Kato ◽  
Kenji Hirohata ◽  
Akira Kano ◽  
Shinya Higashi ◽  
Akihiro Goryu ◽  
...  
Keyword(s):  
Blood Flow ◽  
Coronary Artery ◽  
Boundary Conditions ◽  
Coronary Arteries ◽  
Computational Time ◽  
Ct Image ◽  
Analysis Method ◽  
Fractional Flow ◽  
4D Ct ◽  
Fluid Analysis

Non invasive fractional flow reserve derived from CT coronary angiography (CT-FFR) has to date been typically performed using the principles of computational fluid analysis in which a lumped parameter coronary vascular bed model is assigned to represent the impedance of the downstream coronary vascular networks absent in the computational domain for each coronary outlet. This approach may have a number of limitations. It may not account for the impact of the myocardial contraction and relaxation during the cardiac cycle, patient-specific boundary conditions for coronary artery outlets and vessel stiffness. We have developed a novel approach based on 4D-CT image tracking (registration) and structural and fluid analysis based on one dimensional mechanical model, to address these issues. In our approach, we analyzed the deformation variation of vessels and the volume variation of vessels to better define boundary conditions and stiffness of vessels. We focused on the blood flow and vessel deformation of coronary arteries and aorta near coronary arteries in the diastolic cardiac phase from 70% to 100 %. The blood flow variation of coronary arteries relates to the deformation of vessels, such as expansion and contraction of the cross-sectional area, during this period where resistance is stable, pressure loss is approximately proportional to flow. We used a statistical estimation method based on a hierarchical Bayes model to integrate 4D-CT measurements and structural and fluid analysis data. Under these analysis conditions, we performed structural and fluid analysis to determine pressure, flow rate and CT-FFR. Furthermore, the reduced-order model based on fluid analysis was studied in order to shorten the computational time for 4D-CT-FFR analysis. The consistency of this method has been verified by a comparison of 4D-CT-FFR analysis results derived from five clinical 4D-CT datasets with invasive measurements of FFR. Additionally, phantom experiments of flexible tubes with and without stenosis using pulsating pumps, flow sensors and pressure sensors were performed. Our results show that the proposed 4D-CT-FFR analysis method has the potential to accurately estimate the effect of coronary artery stenosis on blood flow.

scholarly journals Three-dimensional alignment of microvasculature and cardiomyocytes in the developing ventricle

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Maryse Lapierre-Landry ◽  
Hana Kolesová ◽  
Yehe Liu ◽  
Michiko Watanabe ◽  
Michael W. Jenkins
Keyword(s):  
Coronary Artery ◽  
Normal Development ◽  
Fluorescent Dyes ◽  
Developmental Stages ◽  
Three Dimensional ◽  
Left Ventricular ◽  
Vessel Density ◽  
Ventricular Wall ◽  
Major Coronary Artery ◽  
Whole Heart

Abstract While major coronary artery development and pathologies affecting them have been extensively studied, understanding the development and organization of the coronary microvasculature beyond the earliest developmental stages requires new tools. Without techniques to image the coronary microvasculature over the whole heart, it is likely we are underestimating the microvasculature’s impact on normal development and diseases. We present a new imaging and analysis toolset to visualize the coronary microvasculature in intact embryonic hearts and quantify vessel organization. The fluorescent dyes DiI and DAPI were used to stain the coronary vasculature and cardiomyocyte nuclei in quail embryo hearts during rapid growth and morphogenesis of the left ventricular wall. Vessel and cardiomyocytes orientation were automatically extracted and quantified, and vessel density was calculated. The coronary microvasculature was found to follow the known helical organization of cardiomyocytes in the ventricular wall. Vessel density in the left ventricle did not change during and after compaction. This quantitative and automated approach will enable future cohort studies to understand the microvasculature’s role in diseases such as hypertrophic cardiomyopathy where misalignment of cardiomyocytes has been observed in utero.

Intramural Left Coronary Artery in Truncus Arteriosus

2016 ◽  
Vol 9 (1) ◽  
pp. 117-120 ◽  
Author(s):  
Nabil Hussein ◽  
Simone Speggiorin ◽  
Frances Bu’Lock ◽  
Antonio F. Corno
Keyword(s):  
Coronary Artery ◽  
Left Coronary Artery ◽  
Surgical Repair ◽  
Truncus Arteriosus ◽  
Low Cardiac Output ◽  
Output State ◽  
Common Arterial Trunk ◽  
Arterial Trunk ◽  
Definition Of ◽  
Intramural Coronary Artery

An intramural coronary artery in the setting of truncus arteriosus (common arterial trunk) is an uncommon association. Following an uneventful surgical repair, a neonate developed a low cardiac output state deteriorating into cardiac arrest shortly after arrival into the intensive care unit, requiring extracorporeal membrane oxygenation support. Echocardiography and angiography showed occlusion of the left coronary artery, prompting emergency surgical reexploration. A “slit-like” orifice with an intramural left coronary artery was successfully unroofed, allowing full recovery. Full definition of the proximal coronary anatomy beyond the orifices should be investigated preoperatively in truncus arteriosus, as a missed intramural segment could lead to significant morbidity or mortality.

scholarly journals Woven-like change following intracoronary thrombosis recanalization: a case report

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Wei Wen ◽  
Haibo Liu ◽  
Jimin Li ◽  
Qi Zhang
Keyword(s):  
Coronary Artery ◽  
Coronary Intervention ◽  
Distal Segment ◽  
Main Trunk ◽  
Diagnostic Modality ◽  
Spider Web ◽  
Coronary Thrombus ◽  
Definition Of ◽  
Lotus Root Appearance ◽  
The Right

Abstract Background A woven coronary artery is a rare congenital coronary anomaly and incidentally found in coronary angiogram. Coronary angiography is the major diagnostic modality, which shows the main trunk of coronary divides into several channels which later reconnect with normal blood flow (J Int Cardiol 113:121-123 2006). However, some cases and reviews inferred that this characteristic might be mimicked by recanalized coronary thrombus, which occurs following thrombotic occlusion. In some case, the multiple intraluminal channels have a ‘Swiss cheese’, a ‘Spider web-like’, a ‘Honeycomb’ or a ‘Lotus root’ appearance and most of them appear in local segment (Int J Cardiol 186: 239–240, 2015). As these images are nonspecific findings, there is no angiographic uniform definition of intracoronary thrombus. More information about the characteristics and the development of this woven-like structure is needed. Case presentation A 67-year-old male patient was admitted to our hospital because of chest pain. Coronary artery angiogram revealed that the right coronary artery (RCA) divided into multiple thin channels from proximal to distal, which was similar to the so-called woven coronary artery. Compared with his prior coronary angiograms which showed a tiny hazy lesion in distal segment of RCA, we found the woven-like phenomena should be caused by a late-stage recanalized coronary thrombus. Percutaneous coronary intervention (PCI) was performed to restore the RCA flow, and the angina symptom was extremely improved during clinical follow-up. Conclusions The diagnostic criteria of woven coronary artery was based on angiographic image. However, some cases and reviews inferred that thrombotic recanalization might also share the same characteristic. In this case, we collected the baseline angiograms and intracoronary images then successfully diagnosed the woven-like RCA as thrombotic recanalization. For this kind of woven-like coronary artery, PCI could be a better treatment strategy. Detailed history collection and intracoronary image techniques should be emphasized in future clinical practice in the differentiating and treatment of woven-like phenomena.

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