Stereoselectivity of butylidenephthalide on non-adrenergic prejunctional voltage-dependent Ca 2+ channels in prostatic portion of rat vas deferens

2016 ◽  
Vol 786 ◽  
pp. 47-52 ◽  
Author(s):  
Chung-Hung Shih ◽  
Chi-Ming Chen ◽  
Wun-Chang Ko
Keyword(s):  
Vas Deferens ◽  
Rat Vas Deferens ◽  
Voltage Dependent

Ca(2+)-induced inhibition of 45Ca2+ influx and Ca2+ current in smooth muscle of the rat vas deferens

1996 ◽  
Vol 270 (5) ◽  
pp. C1468-C1477 ◽  
Author(s):  
M. A. Khoyi ◽  
T. Ishikawa ◽  
K. D. Keef ◽  
D. P. Westfall
Keyword(s):  
Vas Deferens ◽  
Rat Vas Deferens ◽  
Inhibitory Effects ◽  
Isolated Cells ◽  
Inositol 1,4,5 Trisphosphate ◽  
Voltage Dependent ◽  
Steady State Inactivation ◽  
Inward Currents ◽  
K Concentration ◽  
Ca2 Channels

The present study investigates how changes in intracellular Ca2+ concentration modulate the influx of 45Ca2+ in isolated rat vasa deferentia. Raising extracellular K+ concentration ([K+]0) to > or = 32 mM increased 45Ca2+ influx during the 1st min in solutions containing 0.03-1.5 mM extracellular Ca2+ concentration ([Ca2+]0). During the 6th min in [K+]0 > or = 50 mM, 45Ca2+ influx was less than during the 1st min. This decline in 45Ca2+ influx occurred for [Ca2+]0 > or = 0.4 mM. Procaine potentiated K(+)-stimulated 45Ca2+ influx in 1.5 mM [Ca2+]0 and eliminated the decline of 45Ca2+ influx in low [Ca2-]0. Ryanodine and norepinephrine reduced K(+)-stimulated 45Ca2+ influx. 45Ca2+ content changed with time in accordance with the changes observed in 45Ca2+ influx. In isolated cells, voltage-dependent inward currents inactivated more rapidly with 1.5 mM Ca2+ as the charge carrier than with 1.5 mM Ba2+, and the steady-state inactivation relationship was shifted in the hyperpolarizing direction. Inward current was reduced with either caffeine, ryanodine, or norepinephrine. The inhibitory effects of norepinephrine were abolished by depletion of intracellular Ca2+ stores. These results are compatible with the hypothesis that K(+)-stimulated 45Ca2+ influx declines with time due to Ca(2+)-induced inhibition of Ca2- channels. Ca(2+)- and inositol 1,4,5-trisphosphate-induced releases of Ca2+ from the sarcoplasmic reticulum appear to play an important role in this process.

The oxidation of dopamine by the semicarbazide-sensitive amine oxidase (SSAO) from rat vas deferens

1991 ◽  
Vol 41 (8) ◽  
pp. 1107-1110 ◽  
Author(s):  
JoséM. Lizcano ◽  
Dolors Balsa ◽  
Keith F. Tipton ◽  
Mercedes Unzeta
Keyword(s):  
Vas Deferens ◽  
Amine Oxidase ◽  
Rat Vas Deferens

Mode of Action of 5-Hydroxytryptamine on Isolated Rat Vas Deferens

Nature ◽  
1970 ◽  
Vol 228 (5271) ◽  
pp. 564-565 ◽  
Author(s):  
K. NISHINO ◽  
T. IRIKURA ◽  
I. TAKAYANAGI
Keyword(s):  
Mode Of Action ◽  
Vas Deferens ◽  
Rat Vas Deferens ◽  
Isolated Rat

NS 1619 activates Ca2+-activated K+ currents in rat vas deferens

1997 ◽  
Vol 325 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Yu Huang ◽  
C.-W. Lau ◽  
I.H.M. Ho
Keyword(s):  
Vas Deferens ◽  
Rat Vas Deferens ◽  
K Currents

scholarly journals In vivo fibre optic confocal imaging of microvasculature and nerves in the rat vas deferens and colon

1998 ◽  
Vol 192 (4) ◽  
pp. 489-495 ◽  
Author(s):  
G. D. PAPWORTH ◽  
P. M. DELANEY ◽  
L. J. BUSSAU ◽  
L. T. VO ◽  
R. G. KING
Keyword(s):  
Vas Deferens ◽  
Rat Vas Deferens ◽  
Confocal Imaging ◽  
Fibre Optic

A comparison of histamine effects on the sympathetic neurotransmission of testicular capsule and rat vas deferens

2014 ◽  
Vol 387 (8) ◽  
pp. 719-731 ◽  
Author(s):  
Edilson Dantas da Silva Júnior ◽  
Juliano Quintella Dantas Rodrigues ◽  
Bruno Palmieri de Souza ◽  
Afonso Caricati-Neto ◽  
Aron Jurkiewicz ◽  
...  
Keyword(s):  
Vas Deferens ◽  
Rat Vas Deferens ◽  
Sympathetic Neurotransmission ◽  
Testicular Capsule

Postjunctional supersensitivity of the rat vas deferens and gap junctions

1976 ◽  
Vol 54 (3) ◽  
pp. 412-416 ◽  
Author(s):  
D. M. Paton ◽  
J. Buckland-Nicks ◽  
A. Johns
Keyword(s):  
Electron Microscopy ◽  
Gap Junctions ◽  
Spontaneous Activity ◽  
Vas Deferens ◽  
Rat Vas Deferens ◽  
Sprague Dawley ◽  
Glutaraldehyde Fixation ◽  
Sprague Dawley Rats

Tissues from the duodenum and vas deferens of Sprague–Dawley rats were examined of the rat vas deferens and gap junctions. Can. J. Physiol. Pharmacol. 54, 412–416. by electron microscopy after glutaraldehyde fixation and postosmication. Gap junctions (nexuses) were readily demonstrated in the duodenum in both control and reserpine treated animals (1.0 mg/kg per day for 7 days). However, gap junctions could not be demonstrated in vas deferens. It is concluded that the postjunctional supersensitivity and spontaneous activity induced by reserpine in vas deferens, does not result from the formation of gap junctions.

Contraction of rat vas deferens by cocaine

1967 ◽  
Vol 19 (10) ◽  
pp. 695-695 ◽  
Author(s):  
Stella R. O'Donnell ◽  
Sally E. Hecker
Keyword(s):  
Vas Deferens ◽  
Rat Vas Deferens
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