Recommendations for early diagnosis and intervention in autism spectrum disorders: An Italian–Israeli consensus conference

2014 ◽  
Vol 18 (2) ◽  
pp. 107-118 ◽  
Author(s):  
Ditza A. Zachor ◽  
Paolo Curatolo
Keyword(s):  
Autism Spectrum Disorders ◽  
Early Diagnosis ◽  
Autism Spectrum ◽  
Consensus Conference ◽  
Spectrum Disorders

scholarly journals The Analyses of Possible Indicators of Children With Autism Spectrum Disorders Early Diagnosis

2021 ◽  
Vol 4 (2) ◽  
pp. 60-79
Author(s):  
Kristina Kharatyan
Keyword(s):  
Autism Spectrum Disorders ◽  
Early Diagnosis ◽  
Speech Therapy ◽  
Autism Spectrum ◽  
Speech Development ◽  
Social Adaptation ◽  
Development Communication ◽  
Social Partnership ◽  
Long Time ◽  
Spectrum Disorders

Nowadays autism spectrum disorders (ASD) are on the list of most frequent childish disorders. It is characterized by communicational, behavioural, and emotional difficulties, unique manifestations of cognitive processes, lack of communicational initiative. ASD is a developmental disorder that occurs in early childhood, persists into adulthood, and affects three areas of development: communication, social partnership, and behavior. So, when the means of communication are incomplete or absent, the normal course of the child's development is being disrupted, social adaptation becomes impossible. For the effective organization of speech therapy intervention of children, it is necessary to start child`s rehabilitation work as   possible of the child's development: The author's long time professional experience (15 years) in working with these children indicates that one of the keys to the best effectiveness of communication and speech development is early intervention, which can be organized only after the early detection and diagnosis of children with ASD. One of the prerequisites for early diagnosis is to ensure the continuity of the awareness process among parents, which is the main goal of our article.

scholarly journals Current Progress and Challenges in the Search for Autism Biomarkers

2013 ◽  
Vol 35 ◽  
pp. 55-65 ◽  
Author(s):  
Irina Voineagu ◽  
Hee Jeong Yoo
Keyword(s):  
Autism Spectrum Disorders ◽  
Early Diagnosis ◽  
Biological Markers ◽  
Recent Progress ◽  
Disease Risk ◽  
Autism Spectrum ◽  
Ethical Aspects ◽  
Spectrum Disorders ◽  
Biomarker Research ◽  
Behavioral Criteria

Autism spectrum disorders (ASD) encompass a range of neurodevelopmental conditions that are clinically and etiologically very heterogeneous. ASD is currently diagnosed entirely on behavioral criteria, but intensive research efforts are focused on identifying biological markers for disease risk and early diagnosis. Here, we discuss recent progress toward identifying biological markers for ASD and highlight specific challenges as well as ethical aspects of translating ASD biomarker research into the clinic.

scholarly journals Adaptation of the Questionnaire BISCUIT for the Early Detection of Autism Spectrum Disorders

Reflexio ◽  
2019 ◽  
Vol 12 (2) ◽  
pp. 5-20
Author(s):  
O. N. Pervushina ◽  
K. S. Zemlyanaya ◽  
M. P. Mezentseva
Keyword(s):  
Autism Spectrum Disorders ◽  
Early Diagnosis ◽  
Children With Autism ◽  
Internal Consistency Reliability ◽  
Autism Spectrum ◽  
Autism Traits ◽  
Russian Version ◽  
Validity Criterion ◽  
Cutoff Scores ◽  
Spectrum Disorders

The article presents the adaptation results for “Baby and Infant Screen for Children with aUtIsm Traits (BISCUIT)” questionnaire for early diagnosis of autism spectrum disorders (ASD) in the Russian-speaking sample (n=105). We evaluated the psychometric properties of the Russian version questionnaire: internal consistency reliability, construct validity, criterion-related validity and item discrimination. According to the results of the adaptation, BISCUIT questionnaire has good psychometric indicators, however, cutoff scores should be revised on a standardization sample with a larger number of clinical cases.

scholarly journals Subphenotype-Dependent Disease Markers for Diagnosis and Personalized Treatment of Autism Spectrum Disorders

2012 ◽  
Vol 33 (5) ◽  
pp. 277-288 ◽  
Author(s):  
Valerie W. Hu
Keyword(s):  
Autism Spectrum Disorders ◽  
Early Diagnosis ◽  
Clinical Manifestations ◽  
The United States ◽  
Autism Spectrum ◽  
Individual Outcomes ◽  
Disease Markers ◽  
At Risk Children ◽  
Spectrum Disorders ◽  
Core Symptoms

Autism spectrum disorders (ASD) are a collection of neurodevelopmental disorders that are currently diagnosed solely on the basis of abnormal reciprocal language and social development as well as stereotyped behaviors. Without genetic or molecular markers for screening, individuals with ASD are typically not diagnosed before the age of 2, with milder cases diagnosed much later. Because early diagnosis is tantamount to early behavioral intervention which has been shown to improve individual outcomes, an objective biomarker test that can diagnose at-risk children perinatally is a medical imperative. The rapidly increasing prevalence of ASD in the United States (now estimated at 1 in 88 individuals) also makes early diagnosis and intervention a public health imperative. This article reviews recent genome-wide (genomic) approaches to the identification of disease markers that may be used not only for diagnosis of ASD, but also for the informed development of novel drugs that target specific core symptoms of ASD. Because of the heterogeneity of clinical manifestations associated with the ASD population, this review also addresses the importance of dividing individuals with ASD into clinically relevant subphenotypes in the quest to identify appropriate biomarkers.

Sign in / Sign up

Export Citation Format

Share Document