The predictive role of heat shock protein 27–60 levels in pediatric patients with ataxia telangiectasia

2017 ◽  
Vol 21 ◽  
pp. e215
Author(s):  
A.A. Ozcelik ◽  
P. Perk ◽  
A. Bay ◽  
B. Erbagci ◽  
A. Gok ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Ataxia Telangiectasia ◽  
Pediatric Patients ◽  
Heat Shock Protein 27 ◽  
Predictive Role

scholarly journals The Predictive Role of Heat Shock Proteins 27 and 60 in Pediatric Patients with Ataxia Telangiectasia

2020 ◽  
Vol 26 (4) ◽  
pp. 287-290
Author(s):  
A. Aysima Ozcelik ◽  
◽  
Peren Perk ◽  
Binnur Ozyurt ◽  
Beltinge Demircioglu Kilic ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Proteins ◽  
Ataxia Telangiectasia ◽  
Pediatric Patients ◽  
Predictive Role ◽  
Shock Proteins

Role of Heat Shock Protein 27 in Regulation of Glutathione System and Apoptosis of Jurkat Tumor Cells and Blood Lymphocytes

2015 ◽  
Vol 158 (3) ◽  
pp. 377-379 ◽  
Author(s):  
N. V. Ryazantseva ◽  
E. A. Stepovaya ◽  
O. L. Nosareva ◽  
E. V. Konovalova ◽  
D. S. Orlov ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Tumor Cells ◽  
Heat Shock Protein 27 ◽  
Glutathione System ◽  
Blood Lymphocytes

scholarly journals Targeting Heat Shock Protein 27 in Cancer: A Druggable Target for Cancer Treatment ?

2019 ◽  
Author(s):  
Seul-Ki Choi ◽  
Heejin Kam ◽  
Kye-Young Kim ◽  
Suk In Park ◽  
Yun-Sil Lee
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Cancer Treatment ◽  
Poor Prognosis ◽  
Treatment Resistance ◽  
Therapeutic Agents ◽  
Heat Shock Protein 27 ◽  
Cytoskeletal Remodeling ◽  
Protein Chaperone

Heat shock protein 27 (HSP27), induced by heat shock, environmental, and pathophysiological stressors, is a multi-dimensional protein that acts as a protein chaperone and an antioxidant. HSP27 plays a major role in the inhibition of apoptosis and actin cytoskeletal remodeling. HSP27 is upregulated in many cancers and is associated with poor prognosis, as well as treatment resistance whereby cells are protected from therapeutic agents that normally induce apoptosis. This review highlights the most recent findings and role of HSP27 in cancer, as well as strategies for using HSP27 inhibitors for therapeutic purposes.

scholarly journals Role of estrogen receptor/Sp1 complexes in estrogen-induced heat shock protein 27 gene expression.

1996 ◽  
Vol 10 (11) ◽  
pp. 1371-1378 ◽  
Author(s):  
W Porter ◽  
F Wang ◽  
W Wang ◽  
R Duan ◽  
S Safe
Keyword(s):  
Gene Expression ◽  
Estrogen Receptor ◽  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein 27

The Role of heat shock protein 27 in extravillous trophoblast differentiation

2008 ◽  
Vol 103 (3) ◽  
pp. 719-729 ◽  
Author(s):  
S. Tartakover Matalon ◽  
L. Drucker ◽  
A. Fishman ◽  
A. Ornoy ◽  
M. Lishner
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein 27 ◽  
Extravillous Trophoblast ◽  
Trophoblast Differentiation

Differential Expression of Small Heat Shock Protein 27 (Hsp27) in Ataxia telangiectasia Brains

2009 ◽  
Vol 34 (9) ◽  
pp. 1658-1667 ◽  
Author(s):  
Wenqiang Chen ◽  
Salomon Kuizon ◽  
Bair L. Chiou ◽  
David C. Bolton ◽  
Raju K. Pullarkat ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Differential Expression ◽  
Ataxia Telangiectasia ◽  
Small Heat Shock Protein ◽  
Heat Shock Protein 27

The antiviral role of heat shock protein 27 against red spotted grouper nervous necrosis virus infection in sea perch

2017 ◽  
Vol 70 ◽  
pp. 185-194 ◽  
Author(s):  
Yao Le ◽  
Peng Jia ◽  
Yilin Jin ◽  
Wei Liu ◽  
Kuntong Jia ◽  
...  
Keyword(s):  
Heat Shock ◽  
Virus Infection ◽  
Heat Shock Protein ◽  
Heat Shock Protein 27 ◽  
Nervous Necrosis Virus ◽  
Necrosis Virus ◽  
Sea Perch ◽  
Antiviral Role

scholarly journals Targeting Heat Shock Protein 27 in Cancer: A Druggable Target for Cancer Treatment?

Cancers ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1195 ◽  
Author(s):  
Choi ◽  
Kam ◽  
Kim ◽  
Park ◽  
Lee
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Poor Prognosis ◽  
Treatment Resistance ◽  
Therapeutic Agents ◽  
Heat Shock Protein 27 ◽  
Functional Protein ◽  
Cytoskeletal Remodeling ◽  
Protein Chaperone

Heat shock protein 27 (HSP27), induced by heat shock, environmental, and pathophysiological stressors, is a multi-functional protein that acts as a protein chaperone and an antioxidant. HSP27 plays a significant role in the inhibition of apoptosis and actin cytoskeletal remodeling. HSP27 is upregulated in many cancers and is associated with a poor prognosis, as well as treatment resistance, whereby cells are protected from therapeutic agents that normally induce apoptosis. This review highlights the most recent findings and role of HSP27 in cancer, as well as the strategies for using HSP27 inhibitors for therapeutic purposes.

scholarly journals Phosphorylated heat shock protein 27 as a potential biomarker to predict the role of chemotherapy-induced autophagy in osteosarcoma response to therapy

Oncotarget ◽  
2017 ◽  
Vol 9 (2) ◽  
pp. 1602-1616 ◽  
Author(s):  
Janice M. Santiago-O’Farrill ◽  
Eugenie S. Kleinerman ◽  
Mario G. Hollomon ◽  
Andrew Livingston ◽  
Wei-Lien Wang ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Heat Shock Protein 27 ◽  
Response To Therapy ◽  
Potential Biomarker

scholarly journals The role of heat shock protein 27 in bronchiolitis obliterans syndrome after lung transplantation

2010 ◽  
Vol 29 (7) ◽  
pp. 786-791 ◽  
Author(s):  
Karen L. Wood ◽  
David R. Nunley ◽  
Susan Moffatt-Bruce ◽  
Amy Pope-Harman ◽  
Qin Huang ◽  
...  
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Lung Transplantation ◽  
Bronchiolitis Obliterans ◽  
Heat Shock Protein 27 ◽  
Bronchiolitis Obliterans Syndrome
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