Longitudinal change in patellofemoral cartilage thickness, cartilage T2 relaxation times, and subchondral bone plate area in adolescent vs mature athletes

2017 ◽  
Vol 92 ◽  
pp. 24-29 ◽  
Author(s):  
Adam G. Culvenor ◽  
Wolfgang Wirth ◽  
Susanne Maschek ◽  
Heide Boeth ◽  
Gerd Diederichs ◽  
...  
2006 ◽  
Vol 19 (03) ◽  
pp. 142-146 ◽  
Author(s):  
D. D. Frisbie ◽  
M. W. Cross ◽  
C. W. McIlwraith

SummaryHistological measurements of the thickness of non-calcified and calcified cartilage, as well as the subchondral bone plate in five locations on the femoral trochlea and medial femoral condyles of species were used in preclinical studies of articular cartilage and compared to those of the human knee. Cadaver specimens were obtained of six human knees, as well as six equine, six goat, six dog, six sheep and six rabbit stifle joints (the animal equivalent of the human knee). Specimens were taken from the lateral trochlear ridge, medial trochlear ridge and medial femoral condyle. After histopathological processing, the thickness of non-calcified and calcified cartilage layers, as well as the subchondral bone plate, was measured. Average articular cartilage thickness over five locations were 2.2–2.5 mm for human, 0.3 mm for rabbit, 0.4–0.5 mm for sheep, 0.6–1.3 mm for dog, 0.7–1.5 mm for goat and 1.5–2 mm for horse. The horse provides the closest approximation to humans in terms of articular cartilage thickness, and this approximation is considered relevant in pre-clinical studies of cartilage healing.


2014 ◽  
Vol 32 (10) ◽  
pp. 1356-1361 ◽  
Author(s):  
Christian Egloff ◽  
Jochen Paul ◽  
Geert Pagenstert ◽  
Patrick Vavken ◽  
Beat Hintermann ◽  
...  

2002 ◽  
Vol 11 (2) ◽  
pp. 174-181 ◽  
Author(s):  
Christoph U. Schulz ◽  
Manfred Pfahler ◽  
Hermann M. Anetzberger ◽  
Christoph R. Becker ◽  
Magdalena Müller-Gerbl ◽  
...  

2018 ◽  
Vol 3 (3) ◽  
pp. 2473011418S0048
Author(s):  
Hajo Thermann

Category: Ankle Introduction/Purpose: Severve cartilage lesion is defined by the author as: Cartilage substantial deterioration of the subchondral bone Kissing lesion, tibial and talar lesion. Gross cystic lesion Cartilage damage greater than 1/3 of the talar dome or the tibial platform Slerotic changes of the subchondral bone plate in arthritic cases in severe hindfoot varus or valgus alignment. This paper shows in a case series, exceptional cartilage lesions with the above mentioned pathological changes. The indications, strategies for osteotomies and the treatment strategies in malaligned bipolar, cystic and gross cartilage lesions is explained. Methods: 35 patients with severe circumscript varus / valgus arthritis have been operated by supramalleolar osteotomy (SMOT), 11 of them with (tibial & talar “kissing”) lesions. 70 patients presented bipolar (tibial & talar “kissing”) lesions with correct hindfoot axis. 18 patients had a gross cystic lesion and were additionally treated with filling of the cysts. 2 of them had a “kissing lesion”. Results: All patients received an AMIC procedure (hyaluronic matrix, Hyalofast©) for cartilage reconstruction. The biological healing support was in all cases bone marrow aspirate and ACP© growth factors. The subchondral bone plate was treated aggressively was a power raps or burr according to L. Johnson technique The importance of a supramalleolar and calcaneous osteotomy in a hindfoot malalignment (varus / valgus) as a treatment key aspect for load transfer is elaborated. Planned early implant removal with revision und biological boosting of the cartilage regeneration is a further cornerstone of the treatment. Followup were evaluated by FAOS score Conclusion: This cases series have shown the possibilities for a successfull managing of this severe lesions and offers also its limit in the over all results.


2012 ◽  
Vol 45 ◽  
pp. S154
Author(s):  
Sarah Ronken ◽  
Sebastian Hoechel ◽  
Dieter Wirz ◽  
Magdalena Müller-Gerbl

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