scholarly journals Sentinel lymph node localization and staging with a low-dose of superparamagnetic iron oxide (SPIO) enhanced MRI and magnetometer in patients with cutaneous melanoma of the extremity - The MAGMEN feasibility study

2022 ◽  
Author(s):  
Nushin Mirzaei ◽  
Dimitrios Katsarelias ◽  
Pontus Zaar ◽  
Oscar Jalnefjord ◽  
Iva Johansson ◽  
...  
Keyword(s):  
Lymph Node ◽  
Iron Oxide ◽  
Sentinel Lymph Node ◽  
Feasibility Study ◽  
Cutaneous Melanoma ◽  
Low Dose ◽  
Superparamagnetic Iron Oxide ◽  
Node Localization ◽  
Enhanced Mri

scholarly journals Pre-operative sentinel lymph node localization in breast cancer with superparamagnetic iron oxide MRI: the SentiMAG Multicentre Trial imaging subprotocol

2015 ◽  
Vol 88 (1056) ◽  
pp. 20150634 ◽  
Author(s):  
Joost J Pouw ◽  
Maarten R Grootendorst ◽  
Roland Bezooijen ◽  
Caroline A H Klazen ◽  
Wieger I De Bruin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Iron Oxide ◽  
Sentinel Lymph Node ◽  
Multicentre Trial ◽  
Superparamagnetic Iron Oxide ◽  
Node Localization

Sentinel lymph node identification using superparamagnetic iron oxide particles versus radioisotope: The French Sentimag feasibility trial

2016 ◽  
Vol 113 (5) ◽  
pp. 501-507 ◽  
Author(s):  
Jean-Louis Houpeau ◽  
Marie-Pierre Chauvet ◽  
François Guillemin ◽  
Cécile Bendavid-Athias ◽  
Hélène Charitansky ◽  
...  
Keyword(s):  
Lymph Node ◽  
Iron Oxide ◽  
Sentinel Lymph Node ◽  
Superparamagnetic Iron Oxide ◽  
Feasibility Trial ◽  
Iron Oxide Particles ◽  
Sentinel Lymph Node Identification ◽  
Superparamagnetic Iron Oxide Particles ◽  
Oxide Particles

Moving a neodymium magnet promotes migration of magnetic tracer and increases the monitoring counts on the skin surface of sentinel lymph node in breast cancer

2020 ◽  
Author(s):  
Masujiro Makita ◽  
Eriko Manabe ◽  
Tomoko Kurita ◽  
Hiroyuki Takei ◽  
Seigo Nakamura ◽  
...  
Keyword(s):  
Lymph Node ◽  
Iron Oxide ◽  
Sentinel Lymph Node ◽  
Superparamagnetic Iron Oxide ◽  
Skin Surface ◽  
Neodymium Magnet ◽  
Node Biopsy ◽  
Magnetic Tracer ◽  
Group A ◽  
Movement Group

Abstract Background : We thought that moving a small neodymium magnet would promote migration of the magnetic tracer to the sentinel lymph node (SLN). Higher monitoring counts on the skin surface before incision help us detect SLNs easily and successfully. The aim of the present study was to verify enhancement of the monitoring count on the skin surface in SLN detection by the magnet movement in sentinel lymph node biopsy (SNB) using superparamagnetic iron oxide (SPIO) nanoparticles. Methods: After induction of general anesthesia, superparamagnetic iron oxide nanoparticles were injected sub-dermally into the subareolar area or peritumorally. The neodymium magnet was moved over the skin from the injection site to the axilla to promote migration of the magnetic tracer without massage. A total of 62 patients were enrolled from February 2018 to November 2018; 13 cases were given 20 times magnet movement (Group A), 8 cases were given 1-min magnet movement (Group B), 26 cases were given a short (about 5 min) interval from injection to 1-min magnet movement (Group C), and 15 cases were given a long (about 25 min) interval before 1-min magnet movement by the magnetometer’s head (Group D). In all cases, sentinel node biopsy was conducted using both the radioisotope (RI) and SPIO methods. The monitoring counts on the skin surface were measured by a handheld magnetometer and compared among the 4 groups. Changes in the monitoring count by interval and by magnet movement were evaluated. Results: The identification rates of the SPIO and RI methods were 100% and 95.2%, respectively. The mean monitoring counts of Group A, B, C, and D were 2.39 μT, 2.73 μT, 3.15 μT, and 3.92μT, respectively (p<0.0001; Kruskal-Wallis test) . The monitoring counts were higher with longer magnet movement and with the insertion of an interval. Although there were no relationships between the monitoring count on the skin surface and clinicopathologic factors, magnet movement influenced strongly on the monitoring count on the skin surface. Conclusion: Moving a small neodymium magnet is effective for promoting migration of a magnetic tracer and increasing monitoring counts on the skin surface.

A randomized study comparing different doses of superparamagnetic iron oxide tracer for sentinel lymph node biopsy in breast cancer: The SUNRISE study

2020 ◽  
Vol 46 (12) ◽  
pp. 2195-2201
Author(s):  
Isabel T. Rubio ◽  
Roberto Rodriguez-Revuelto ◽  
Martin Espinosa-Bravo ◽  
Christian Siso ◽  
Joaquin Rivero ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Iron Oxide ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Randomized Study ◽  
Superparamagnetic Iron Oxide ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
Different Doses

scholarly journals Superparamagnetic iron oxide as a tracer for sentinel lymph node detection in uterine cancer: a pilot study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Kosuke Murakami ◽  
Yasushi Kotani ◽  
Ayako Suzuki ◽  
Hisamitsu Takaya ◽  
Hidekatsu Nakai ◽  
...  
Keyword(s):  
Lymph Node ◽  
Iron Oxide ◽  
Pilot Study ◽  
Sentinel Lymph Node ◽  
Uterine Cancer ◽  
Superparamagnetic Iron Oxide ◽  
Sentinel Lymph Node Detection
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