Experimental and theoretical investigation of interaction between bovine serum albumin and the mixture of caffeic acid and salicylic acid as the antioxidants

2017 ◽  
Vol 255 ◽  
pp. 428-441 ◽  
Author(s):  
Ali Benvidi ◽  
Masoud Rezaeinasab ◽  
Sajjad Gharaghani ◽  
Saleheh Abbasi ◽  
Hamid R. Zare
Keyword(s):  
Salicylic Acid ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Caffeic Acid ◽  
Theoretical Investigation ◽  
Bovine Serum

Studies on the interaction of salicylic acid and its monohydroxy substituted derivatives with bovine serum albumin

2021 ◽  
Vol 546 ◽  
pp. 111182
Author(s):  
Deying Meng ◽  
Huangmei Zhou ◽  
Jianhua Xu ◽  
Sanjun Zhang
Keyword(s):  
Salicylic Acid ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Bovine Serum

In vitro study of caffeic acid — bovine serum albumin interaction

1988 ◽  
Vol 13 (1) ◽  
pp. 11-14 ◽  
Author(s):  
T. Adzet ◽  
J. Camarasa ◽  
E. Escubedo ◽  
M. Merlos
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Caffeic Acid ◽  
Bovine Serum ◽  
In Vitro Study ◽  
Vitro Study

Physically crosslinked salicylate-based poly (N-isopropylacrylamide-co-acrylic acid) hydrogels for protein delivery

2017 ◽  
Vol 33 (2) ◽  
pp. 224-236 ◽  
Author(s):  
Bahar Demirdirek ◽  
Kathryn E Uhrich
Keyword(s):  
Salicylic Acid ◽  
Bovine Serum Albumin ◽  
Acrylic Acid ◽  
Serum Albumin ◽  
Bovine Serum ◽  
Protein Delivery ◽  
Temperature Sensitive ◽  
Polymer Systems ◽  
Physical Interactions ◽  
Physically Crosslinked

Physically crosslinked hydrogels were developed via solvent casting methods using a temperature-sensitive polymer, poly( N-isopropylacrylamide- co-acrylic acid), and a therapeutic polymer, salicylate-based poly(anhydride-esters), to concurrently release salicylic acid and bovine serum albumin in a sustained manner. The physical interactions between the two polymer systems were confirmed using Fourier transform infrared spectroscopy. The crosslinked polymers were porous, thus able to encapsulate bovine serum albumin (23 wt%) and then released the protein in a sustained fashion over 96 h. Concurrently, the hydrogel releases salicylic acid in a sustained manner up to 120 h. Hydrogel systems were cytocompatible at relevant therapeutic concentrations. These hydrogel systems can be used for simultaneous delivery of salicylic acid and protein to achieve synergic effects.

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