scholarly journals Associations of urinary concentrations of phthalate metabolites, bisphenol A, and parabens with obesity and diabetes mellitus in a Korean adult population: Korean National Environmental Health Survey (KoNEHS) 2015–2017

2021 ◽  
Vol 146 ◽  
pp. 106227
Author(s):  
Inae Lee ◽  
Young Joo Park ◽  
Min Joo Kim ◽  
Sunmi Kim ◽  
Sohyeon Choi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Bisphenol A ◽  
Environmental Health ◽  
Health Survey ◽  
Adult Population ◽  
Phthalate Metabolites ◽  
Obesity And Diabetes ◽  
Korean Adult ◽  
National Environmental

scholarly journals Association between urinary polycyclic aromatic hydrocarbons and hypertension in the Korean population: data from the Second Korean National Environmental Health Survey (2012–2014)

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Tae-Woo Lee ◽  
Dae Hwan Kim ◽  
Ji Young Ryu
Keyword(s):  
Cardiovascular Disease ◽  
Polycyclic Aromatic Hydrocarbons ◽  
Environmental Health ◽  
Health Survey ◽  
Aromatic Hydrocarbons ◽  
Adult Population ◽  
Pah Metabolites ◽  
Polycyclic Aromatic ◽  
Korean Adult ◽  
National Environmental

Abstract Polycyclic aromatic hydrocarbons (PAHs) are environmental and occupational pollutants derived from incomplete combustion of organic materials, including wood and fossil fuels. Epidemiological studies have evaluated the association between PAH exposure and hypertension or cardiovascular disease in the general population, but the evidence is limited. In this study, we evaluated the association between urinary PAH metabolites and hypertension in the Korean adult population. A total of 6478 adults who participated in the Second Korean National Environmental Health Survey (2012–2014) were included. The differences in urinary concentrations of four PAH metabolites, including 1-hydroxypyrene, 2-hydroxyfluorene, 1-hydroxyphenanthrene, and 2-naphthol, were compared according to hypertension status using a general linear model. Adjusted odds ratios (aORs) for hypertension were calculated according to the quartile groups of urinary PAH metabolites after adjusting for age, sex, body mass index (BMI), smoking, and alcohol consumption in multiple logistic regression analyses. The estimated mean concentrations of urinary 1-hydroxyphenanthrene were significantly higher in the hypertension group than in the non-hypertension group. In 1-hydroxyphenanthrene, the OR for hypertension was significantly higher in the third and fourth quartile groups than in the first quartile group (third: OR 1.707, 95% CI 1.203–2.423, fourth: OR 1.604, 95% CI 1.158–2.223). No significant associations were detected for the other metabolites. Our results suggest an association between exposure to PAHs and hypertension in a Korean adult population. Further studies are required to evaluate the effects of low-dose long-term exposure to PAHs on hypertension and cardiovascular disease.

scholarly journals Characterization of urinary cotinine concentrations among non-smoking adults in smoking and smoke-free homes in the Korean national environmental health survey (KoNEHS) cycle 3 (2015–2017)

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jeonghoon Kim ◽  
In-Keun Shim ◽  
Soo Ran Won ◽  
Jungmin Ryu ◽  
Jongchun Lee ◽  
...  
Keyword(s):  
Environmental Health ◽  
Health Survey ◽  
Tobacco Smoke ◽  
Smoking Status ◽  
Adult Population ◽  
Geometric Mean ◽  
Urinary Cotinine ◽  
Ventilation Duration ◽  
National Environmental ◽  
Cotinine Concentration

Abstract Background Although many indoor public places have implemented smoke-free regulations, private homes have remained sources of tobacco smoke pollutants. This study examined differences in urinary cotinine concentrations in the Korean non-smoking adult population between living in smoking and smoke-free homes, and the relationship of urinary cotinine concentrations with socio-demographic factors in smoke-free homes. Methods Samples from 2575 non-smoking adults (≥19 years old) in the Korean National Environmental Health Survey cycle 3 (2015–2017), a representative Korean study, were used. Smoking and smoke-free homes were defined based on whether there were smokers at homes. Weighted linear regression models were used to determine urinary cotinine concentrations and identify factors associated with urinary cotinine. Results The geometric mean of urinary cotinine concentrations for non-smoking adults living in smoking homes was 2.1 μg/L (95% confidence interval [CI] = 1.8–2.4), which was significantly higher than the mean of 1.3 μg/L (95% CI = 1.2–1.4) for those living in smoke-free homes. Urinary cotinine concentrations were different significantly by home smoking status in most socio-demographic subgroups. Data from smoke-free home showed urinary cotinine concentration in adults was significantly higher in those who lived in homes with ventilation duration < 30 min/day, those who spent more time indoors at home, those who spent less time outdoors, and those who worked in non-manual or manual occupations. Conclusions The urinary cotinine concentration in Korean non-smoking adults living in smoking homes was higher than that in adults living in smoke-free homes. Even in smoke-free homes, home-related factors, such as ventilation duration and time spent indoors, were associated with urinary cotinine concentration. Further study is warranted to examine potential sources of tobacco smoke pollution in smoke-free homes.

scholarly journals The association between urinary bisphenol A levels and nonalcoholic fatty liver disease in Korean adults: Korean National Environmental Health Survey (KoNEHS) 2015-2017

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Sang Joon An ◽  
Eun-Jung Yang ◽  
Subin Oh ◽  
Kyong Jin Park ◽  
Taehyen Kim ◽  
...  
Keyword(s):  
Liver Disease ◽  
Bisphenol A ◽  
Fatty Liver ◽  
Environmental Health ◽  
Nonalcoholic Fatty Liver Disease ◽  
Health Survey ◽  
Fatty Liver Disease ◽  
Nonalcoholic Fatty Liver ◽  
Hepatic Diseases ◽  
National Environmental

Abstract Background Nonalcoholic fatty liver disease (NAFLD) is becoming a global health problem. Bisphenol A (BPA), one of most widely used environmental chemicals, is suspected to be a contributor to the development NAFLD. This study was performed to examine the relationship between human BPA levels and risk of NAFLD. Methods The data (n = 3476 adults: 1474 men and 2002 women) used in this study were obtained from the Korean National Environmental Health Survey III (2015-2017). BPA levels were measured in urine samples. NAFLD was defined using hepatic steatosis index after exclusion of other causes of hepatic diseases. Results There was a significant linear relationship between the elevated urinary BPA concentrations and risk of NAFLD. In a univariate analysis, odds ratio (OR) of the highest quartile of urinary BPA level was 1.47 [95% confidence interval (CI) 1.11-1.94] compared to the lowest quartile. After adjusted with covariates, the ORs for NAFLD in the third and fourth quartiles were 1.31 [95% CI 1.03-1.67] and 1.32 [95% CI 1.03–1.70], respectively. Conclusions Urinary BPA levels are positively associated with the risk of NAFLD in adults. Further experimental studies are needed to understand the molecular mechanisms of BPA on NAFLD prevalence.

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