Combining elemental analysis of toenails and machine learning techniques as a non-invasive diagnostic tool for the robust classification of type-2 diabetes

2019 ◽  
Vol 115 ◽  
pp. 245-255 ◽  
Author(s):  
Jake A. Carter ◽  
Christina S. Long ◽  
Beth P. Smith ◽  
Thomas L. Smith ◽  
George L. Donati
Author(s):  
Angela Pimentel ◽  
Hugo Gamboa ◽  
Isa Maria Almeida ◽  
Pedro Matos ◽  
Rogério T. Ribeiro ◽  
...  

Heart diseases and stroke are the number one cause of death and disability among people with type 2 diabetes (T2D). Clinicians and health authorities for many years have expressed interest in identifying individuals at increased risk of coronary heart disease (CHD). Our main objective is to develop a prognostic workflow of CHD in T2D patients using a Holter dataset. This workflow development will be based on machine learning techniques by testing a variety of classifiers and subsequent selection of the best performing system. It will also assess the impact of feature selection and bootstrapping techniques over these systems. Among a variety of classifiers such as Naive Bayes (NB), Random Forest (RF), Support Vector Machine (SVM), Alternating Decision Tree (ADT), Random Tree (RT) and K-Nearest Neighbour (KNN), the best performing classifier is NB. We achieved an area under receiver operating characteristics curve (AUC) of 68,06% and 74,33% for a prognosis of 3 and 4 years, respectively.


Author(s):  
Angela Pimentel ◽  
Hugo Gamboa ◽  
Isa Maria Almeida ◽  
Pedro Matos ◽  
Rogério T. Ribeiro ◽  
...  

Heart diseases and stroke are the number one cause of death and disability among people with type 2 diabetes (T2D). Clinicians and health authorities for many years have expressed interest in identifying individuals at increased risk of coronary heart disease (CHD). Our main objective is to develop a prognostic workflow of CHD in T2D patients using a Holter dataset.. This workflow development will be based on machine learning techniques by testing a variety of classifiers and subsequent selection of the best performing system. It will also assess the impact of feature selection and bootstrapping techniques over these systems. Among a variety of classifiers such as Naive Bayes (NB), Random Forest (RF), Support Vector Machine (SVM), Alternating Decision Tree (ADT), Random Tree (RT) and K-Nearest Neighbour (KNN), the best performing classifier is NB. We achieved an area under receiver operating characteristics curve (AUC) of 68,06% and 74,33% for a prognosis of 3 and 4 years, respectively.


2021 ◽  
Vol 69 ◽  
pp. 102855
Author(s):  
Miguel Sanchez-Brito ◽  
Francisco J. Luna-Rosas ◽  
Ricardo Mendoza-Gonzalez ◽  
Gustavo J. Vazquez-Zapien ◽  
Julio C. Martinez-Romo ◽  
...  

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