This chapter describes the recognition and associations of the syndrome of attention deficit hyperactivity disorder (ADHD), with special reference to the multitude of associated problems. Inattentiveness, overactivity, and impulsiveness are behaviour styles that predict later disadvantage in education, employment, physical health, substance use, mental health, and personal relationships. They very often coexist with features of oppositional disorders, anxiety, and the autism spectrum. These are considered both as differential diagnoses and as multiple morbidities needing to be recognized. Several cognitive limitations, including in executive function, can be identified by psychological testing. Genetic inheritance is a powerful influence. Neuroimaging is detecting an increasing number of changes in brain structure and function. The problems are widespread, but recognition of the syndrome varies between countries. The diagnosis is increasing in frequency over time. Treatment with stimulant medication is often helpful, but there is considerable controversy about how widely to apply it.
Effect of brain structure and function on reward anticipation in children and adults with attention deficit hyperactivity disorder combined subtype