DISCOVERY BIOLOGY OF NEUROPSYCHIATRIC SYNDROMES: A CENTER FOR INTEGRATING CLINICAL MEDICINE AND BASIC SCIENCE (DBNS): INTEGRATING CLINICAL PSYCHIATRY AND BASIC SCIENCE

Translational research turns fundamental new science and innovations into a product that has value to the public. The process is difficult because it combines a variety of diverse disciplines and skills from basic science, clinical medicine, engineering, business, public health, laws and regulations. These areas are so wide apart that it is very difficult to combine. The author has engaged in translational research since the early 1980’s and will describe the processes, pitfalls and rewards through typical examples from his projects that include: development of imaging monitored cryosurgery from concept to treatment of hundreds of thousands of patients, transgenes in food engineering from basic science to a twenty year wait for FDA approval, microelectroporation from basic concept to incorporation of the technology by numerous companies and non-thermal irreversible electroporation from basic concept to current clinical use in over 50 hospitals and over thousand treated patients.

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Jung's Contribution to Clinical Psychiatry

Proceedings of the Royal Society of Medicine ◽

10.1177/003591573502800813 ◽

1935 ◽

Vol 28 (8) ◽

pp. 1051-1064

Author(s):

Murdo Mackenzie

Keyword(s):

Clinical Psychiatry ◽

Clinical Medicine ◽

Psychological Adaptation ◽

Adequate Description ◽

Unique Method ◽

Basic Functions ◽

Possible Cause ◽

Better Than

This attempt to correlate Jung's work with practical psychiatry is concerned mainly with his conception of clinical types. Jung went far away from the provinces of clinical medicine and psychiatry for his evidence, and the possible cause for this is discussed. He expands his view of introversion and extraversion, and so the suggestion is made that for practical purposes his early limitation of these terms should be maintained. The difficulties encountered in type description by comparison and contrast are emphasized. The value of his conception of basic functions is discussed and criticized. A review is made of the personalities he describes, and a simplification of his resulting classification suggested for practical purposes. The notion is put forward that Jung describes one type in psychological adaptation much better than any others, and it is hinted that his psycho-pathological description of this type in nerve disorder constitutes his main contribution to clinical psychiatry. A review of the treatable nerve disorders suggests that this disorder has received more adequate description from Jung than any other, and reveals a unique method of investigation and therapy. This does not apply to his other descriptions. Possibly some of the vagueness attributed to Jung is because he did not give this disorder an adequate diagnosis, and an explanation for this is offered. The correlation between the simplified classification and the classification of treatable nerve disorders is close, and it is suggested that this constitutes Jung's contribution to clinical psychiatry in general. The application of Jung's principles is of daily help to the practising psychiatrist.

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A new PhD training track: a proposal to improve basic science teaching.

AJP Advances in Physiology Education ◽

10.1152/advances.1997.272.6.s36 ◽

1997 ◽

Vol 272 (6) ◽

pp. S36 ◽

Cited By ~ 2

Author(s):

J J Smith ◽

S M Koethe ◽

H V Forster

Keyword(s):

Medical Education ◽

Training Program ◽

Science Teaching ◽

Basic Science ◽

Clinical Medicine ◽

Limited Commitment ◽

Integrative Physiology ◽

Advantages And Disadvantages ◽

The Future ◽

Medical Basic Science

There has been increasing criticism of medical basic science teaching; much of this has focused on overcrowding of the curriculum, inadequate application to clinical medicine, and the limited commitment of the faculty to teach. We have analyzed some of the factors that may contribute to these complaints, such as the fragmentation of physiology and the conflicting roles of the medical basic scientist. We have also reviewed some previous suggestions for improving basic science teaching. We suggest that a basic scientist with a background of integrative physiology, pharmacology, anatomy, and pathology, with a special emphasis on pathophysiology, would be well qualified to assume an important role in the medical education of the future. Because there is at present no established training program of this type, we have proposed a PhD training track with this objective and have listed some of the advantages and disadvantages of such a program.

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