Sensory processing disorders, duration of current episode, and severity of side effects in major affective and anxiety disorders

2016 ◽  
Vol 33 (S1) ◽  
pp. s224-s225
Author(s):  
G. Serafini ◽  
B. Engel-Yeger ◽  
G.H. Vazquez ◽  
M. Pompili ◽  
M. Amore
Keyword(s):  
Side Effects ◽  
Anxiety Disorders ◽  
Sensory Processing ◽  
Sensory Input ◽  
Sensory Sensitivity ◽  
Illness Duration ◽  
Medication Side Effects ◽  
Duration Of Untreated Illness ◽  
Medication Side ◽  
Sensory Processing Disorders

IntroductionLonger duration of untreated illness, longer duration of current episode, and severity of medication side effects may negatively influence the psychosocial functioning in major affective and anxiety disorders. Studies also suggested the involvement of sensory perception in emotional and psychopathological processes.ObjectiveThe objective of this study is to investigate the nature of the association between duration of untreated illness, duration of current episode, and severity of medication side effects.AimsThe study is aimed to examine the relationship between sensory processing disorders (SPD), duration of untreated illness, duration of current illness episode, and the severity of side effects related to psychoactive medications.MethodsThe sample included 178 participants with an age ranging from 17 to 85 years (mean = 53.84 ± 15.55); psychiatric diagnoses were as follow: unipolar major depressive disorder (MDD) (50%), bipolar disorder (BD) (33.7%), and anxiety disorders (16.3%). subjects completed a socio-demographic questionnaire, the Udvalg for Kliniske Undersøgelser (UKU), and Adolescent/Adult Sensory Profile (AASP) questionnaire.ResultsLonger duration of current episode correlated with greater registration of sensory input and lower avoidance from sensory input among unipolar patients, lower registration of sensory input, and higher tendency for sensory sensitivity/sensation avoidance among bipolar participants. In addition? longer duration of current episode correlated with lower sensory sensitivity/avoidance among anxiety participants, respectively. Mean UKU total scores were associated with lower sensory sensitivity among bipolar individuals as well.ConclusionsSPD expressed in either hypo-/hypersensitivity may be used to clinically characterize subjects with major affective and anxiety disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Medication side effects

BMJ ◽  
2010 ◽  
Vol 341 (sep15 2) ◽  
pp. c4999-c4999
Keyword(s):  
Side Effects ◽  
Medication Side Effects ◽  
Medication Side

scholarly journals Cutaneous Effects of Notch Inhibitor Therapy: A Report of Two Cases

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Claire J. Wiggins ◽  
Susan Y. Chon
Keyword(s):  
Side Effects ◽  
Notch Signaling ◽  
Hidradenitis Suppurativa ◽  
Disease Pathogenesis ◽  
Cutaneous Side Effects ◽  
Medication Side Effects ◽  
Medication Side ◽  
Notch Pathways ◽  
Inhibitor Treatment

As aberrant Notch signaling has been linked to cancerous growth, Notch inhibitors represent a novel category of targeted oncological therapy. Notch pathways in tumor cells may contribute to proliferation or limit apoptosis and differentiation. Healthy skin differentiation and homeostasis are reliant on normal Notch expression, and disruption of this signaling has been implicated in dermatological conditions such as hidradenitis suppurativa, psoriasis, atopic dermatitis, and lichen planus. Here, we describe two cases of patients with cutaneous side effects from Notch inhibitor treatment for adenoid cyst carcinoma (ACC) and review the role of Notch signaling in skin disease. By illuminating connections between medication side effects and disease pathogenesis, our goal is to increase awareness of the cutaneous side effects of Notch inhibitor treatment.

Beliefs about medications predict adherence to antidepressants in older adults

2011 ◽  
Vol 24 (1) ◽  
pp. 159-169 ◽  
Author(s):  
Waleed Fawzi ◽  
Mohamed Yousry Abdel Mohsen ◽  
Abdel Hamid Hashem ◽  
Suaad Moussa ◽  
Elizabeth Coker ◽  
...  
Keyword(s):  
Side Effects ◽  
Rating Scale ◽  
Poor Response ◽  
Self Report ◽  
Poor Adherence ◽  
Response To Treatment ◽  
Medication Side Effects ◽  
Beliefs About Medicines ◽  
Medication Side ◽  
Highly Correlated

ABSTRACTBackground: Adherence to treatment is a complex and poorly understood phenomenon. This study investigates the relationship between older depressed patients’ adherence to antidepressants and their beliefs about and knowledge of the medication.Methods: Assessment was undertaken of 108 outpatients over the age of 55 years diagnosed with depressive disorder and treated for at least four weeks with antidepressants. Adherence was assessed using two self-report measures: the Medication Adherence Rating Scale (MARS) and a Global Adherence Measure (GAM). Potential predictors of adherence investigated included sociodemographic, medication and illness variables. In addition, 33 carers were interviewed regarding general medication beliefs.Results: 56% of patients reported 80% or higher adherence on the GAM. Sociodemographic variables were not associated with adherence on the MARS. Specific beliefs about medicines, such as “my health depends on antidepressants” (necessity) and being less worried about becoming dependant on antidepressants (concern) were highly correlated with adherence. General beliefs about medicines causing harm or being overprescribed, experiencing medication side-effects and severity of depression also correlated with poor adherence. Linear regression with the MARS as the dependent variable explained 44.3% of the variance and showed adherence to be higher in subjects with healthy specific beliefs who received more information about antidepressants and worse with depression severity and autonomic side-effects.Conclusions: Our findings strongly support a role for specific beliefs about medicines in adherence. Challenging patients’ beliefs, providing information about treatment and discussing side-effects could improve adherence. Poor response to treatment and medication side-effects can indicate poor adherence and should be considered before switching medications.

Effective assessment of psychotropic medication side effects using PsyLOG mobile application

2018 ◽  
Vol 192 ◽  
pp. 211-212 ◽  
Author(s):  
Martina Rojnic Kuzman ◽  
Olivier Andlauer ◽  
Kai Burmeister ◽  
Boris Dvoracek ◽  
Rebekka Lencer ◽  
...  
Keyword(s):  
Side Effects ◽  
Psychotropic Medication ◽  
Mobile Application ◽  
Medication Side Effects ◽  
Medication Side ◽  
Effective Assessment
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