scholarly journals The evolution of long noncoding RNA acceptance in prostate cancer initiation, progression, and its clinical utility in disease management

2019 ◽  
Vol 76 (5) ◽  
pp. 546-559 ◽  
Author(s):  
Varune Rohan Ramnarine ◽  
Maxim Kobelev ◽  
Ewan A. Gibb ◽  
Mannan Nouri ◽  
Dong Lin ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Disease Management ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Clinical Utility ◽  
Cancer Initiation

scholarly journals Retraction: Long noncoding RNA PCA3 regulates glycolysis, viability and apoptosis by mediating the miR-1/CDK4 axis in prostate cancer

RSC Advances ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 5894-5894
Author(s):  
Laura Fisher
Keyword(s):  
Prostate Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna

Retraction of ‘Long noncoding RNA PCA3 regulates glycolysis, viability and apoptosis by mediating the miR-1/CDK4 axis in prostate cancer’ by Shuo Gu et al., RSC Adv., 2018, 8, 37564–37572, DOI: 10.1039/C8RA08083F

The function of long noncoding RNA HOTAIRM1 in the progression of prostate cancer cells

Andrologia ◽  
2020 ◽  
Author(s):  
Lei Wang ◽  
Longning Wang ◽  
Qingfen Wang ◽  
Bahman Yosefi ◽  
Sen Wei ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prostate Cancer Cells

scholarly journals Discovery of a novel long noncoding RNA overlapping the LCK gene that regulates prostate cancer cell growth

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Huy Q. Ta ◽  
Hilary Whitworth ◽  
Yi Yin ◽  
Mark Conaway ◽  
Henry F. Frierson ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Growth ◽  
Cancer Cell ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Prostate Cancer Cell ◽  
Cancer Cell Growth

Knockdown of long noncoding RNA AC245100.4 inhibits the tumorigenesis of prostate cancer cells via the STAT3/NR4A3 axis

Epigenomics ◽  
2021 ◽  
Author(s):  
Chi Liu ◽  
Ping Lin ◽  
Jiabin Zhao ◽  
Hui Xie ◽  
Rou Li ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Rna Sequencing ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Transcriptional Repressor ◽  
Sequencing Analysis ◽  
Loss Of Function ◽  
Prostate Cancer Cells ◽  
Rna Immunoprecipitation

Aim: To explore the role and mechanism of long noncoding RNA AC245100.4 and NR4A3 in prostate cancer (PCa). Methods: RNA-sequencing analysis was used to detect the downstream genes of AC245100.4. A series of gain- and loss-of-function approaches were used to investigate the roles of AC245100.4 and NR4A3. RNA immunoprecipitation was performed to examine the interaction between AC245100.4 and STAT3. Results: AC245100.4 was significantly upregulated in PCa cells and tissues. Knockdown of AC21500.4 significantly inhibited the tumorigenesis of PCa cells. Mechanistically, AC245100.4 deregulated the transcription of NR4A3 via increasing p-STAT3, which acted as a transcriptional repressor of NR4A3. Conclusion: Knockdown of lncRNA AC245100.4 inhibits the tumorigenesis of PCa cells via the STAT3/ NR4A3 axis.

scholarly journals Long noncoding RNA PCA3 regulates glycolysis, viability and apoptosis by mediating the miR-1/CDK4 axis in prostate cancer

RSC Advances ◽  
2018 ◽  
Vol 8 (66) ◽  
pp. 37564-37572 ◽  
Author(s):  
Shuo Gu ◽  
Xiaobing Niu ◽  
Fei Mao ◽  
Zongyuan Xu
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Aerobic Glycolysis ◽  
Prostate Cancer Cells

We proved that PCA3 regulated aerobic glycolysis, viability and apoptosis by regulating the miR-1/CDK4 axis in prostate cancer cells.

scholarly journals Development and prospective multicenter evaluation of the long noncoding RNA MALAT-1 as a diagnostic urinary biomarker for prostate cancer

Oncotarget ◽  
2014 ◽  
Vol 5 (22) ◽  
pp. 11091-11102 ◽  
Author(s):  
Fubo Wang ◽  
Shancheng Ren ◽  
Rui Chen ◽  
Ji Lu ◽  
Xiaolei Shi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Urinary Biomarker
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